期刊
NUCLEIC ACIDS RESEARCH
卷 44, 期 7, 页码 2987-2999出版社
OXFORD UNIV PRESS
DOI: 10.1093/nar/gkw151
关键词
-
资金
- National Institutes of Health [GM086663, AT007886]
- Defense Advanced Research Agency [HR0011-11-2-0002]
- Human Frontiers Science Program [RGP0054/2013]
- Oxford University Press-NAR
The past decade of synthetic biology research has witnessed numerous advances in the development of tools and frameworks for the design and characterization of biological systems. Researchers have focused on the use of RNA for gene expression control due to its versatility in sensing molecular ligands and the relative ease by which RNA can be modeled and designed compared to proteins. We review the recent progress in the field with respect to RNA-based genetic devices that are controlled through small molecule and protein interactions. We discuss new approaches for generating and characterizing these devices and their underlying components. We also highlight immediate challenges, future directions and recent applications of synthetic RNA devices in engineered biological systems.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据