☆ 3.8 Editorial Material

Computational optical phase imaging: From digital holographic interferometry to intensity diffraction tomography

CHINESE SCIENCE BULLETIN-CHINESE (2023)

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Summary: We propose a new label-free 3D microscopy technique that can retrieve the 3D refractive index distribution of biological samples through 3D intensity measurements. This technique allows for incoherent 3D phase-contrast imaging without the need for interferometric detection. It provides strong defocus phase contrast and better optical sectioning capabilities, making it suitable for high-resolution tomography of thick biological samples. The technique was validated on various unlabeled fixed and live samples, demonstrating its potential for widespread biological and medical applications.

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