The impact of risk factors on aspirin's efficacy for the prevention of preterm birth

Article Medicine, General & Internal

Estimated Prevalence of Risk Factors for Preeclampsia Among Individuals Giving Birth in the US in 2019

Sarahn M. Wheeler et al.

Summary: The study found that in 2019, out of 3,695,019 pregnancies in the United States, 528,778 had no risk factors, 169,540 had one or more high-risk factors, and 2,996,701 had one or more moderate-risk factors. Multifetal gestation was the most common high-risk factor, while low socioeconomic status was the most common moderate-risk factor. According to the 2021 criteria, 3,166,241 pregnant patients (85.7%) were eligible for LDA for preeclampsia prevention.

JAMA NETWORK OPEN (2022)

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Review Medicine, General & Internal

Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality Updated Evidence Report and Systematic Review for the US Preventive Services Task Force

Jillian T. Henderson et al.

Summary: This study includes 23 randomized clinical trials involving 26,952 participants and found that daily low-dose aspirin during pregnancy can reduce serious perinatal outcomes for individuals at increased risk for preeclampsia, without evident harm.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

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Article Medicine, General & Internal

Nativity-Related Disparities in Preeclampsia and Cardiovascular Disease Risk Among a Racially Diverse Cohort of US Women

Ellen Boakye et al.

Summary: The study found associations between maternal nativity and duration of US residence with preeclampsia among non-Hispanic Black women, while no such associations were observed among Hispanic and non-Hispanic White women. Further research is needed to understand the factors contributing to these disparities, especially among non-Hispanic Black women.

JAMA NETWORK OPEN (2021)

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Article Medicine, General & Internal