The recent outbreaks of Marburg virus disease in African countries are indicating potential threat to the global public health: Future prediction from historical data

Marburg virus disease (MVD) caused by the Marburg virus has a high mortality rate. Rousettus aegyptiacus fruit bats act as the natural reservoir host of the virus. But it can also potentially be transmitted from person to person through direct contact with body secretions. The recent outbreaks have already killed seven people out of nine confirmed cases in Equatorial Guinea and five patients out of eight confirmed cases in Tanzania. In the recent past, Ghana reported three MVD cases and two associated deaths in 2022. Specific treatments or vaccines are unavailable for MVD, and supportive care is the primary treatment option. The history of MVD outbreaks and the current scenario show its potential to become an emerging threat to global public health. The recent outbreaks in Tanzania and Equatorial Guinea have already caused a high fatality rate. The absence of effective treatment and vaccines raises concerns about the potential to cause widespread harm. Besides, its capacity for human-to-human transmission and potential to cross the country's border could result in a multicountry outbreak. Therefore, we recommend intensive surveillance of MVD, preventative measures, and early detection to limit the spread of the disease and prevent another pandemic.

Automated summary

Marburg virus disease (MVD) caused by the Marburg virus has a high mortality rate. Fruit bats act as the natural reservoir host of the virus, but it can also be transmitted from person to person through direct contact with body secretions. Recent outbreaks in Equatorial Guinea and Tanzania have resulted in a significant number of deaths, and Ghana has also reported cases and deaths. There are no specific treatments or vaccines available for MVD, highlighting the potential for widespread harm and the need for intensive surveillance and preventative measures.