期刊
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
卷 70, 期 -, 页码 206-216出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.neubiorev.2016.05.020
关键词
Adolescence; Adrenal; HPA axis; Hypothalamus; Pituitary; Puberty; Stressor
资金
- National Institutes of Health [MH-090224]
- National Science Foundation [IOS-1022148, IOS-1456577]
- Direct For Biological Sciences
- Division Of Integrative Organismal Systems [1456577] Funding Source: National Science Foundation
Adolescent development is marked by many changes in neuroendocrine function, resulting in both immediate and long-term influences on an individual's physiology and behavior. Stress-induced hormonal responses are one such change, with adolescent animals often showing different patterns of hormonal reactivity following a stressor compared with adults. This review will describe the unique ways in which adolescent animals respond to a variety of stressors and how these adolescent-related changes in hormonal responsiveness can be further modified by the sex and previous experience of the individual. Potential central and peripheral mechanisms that contribute to these developmental shifts in stress reactivity are also discussed. Finally, the short- and long-term programming effects of chronic stress exposure during adolescence on later adult hormonal responsiveness are also examined. Though far from a clear understanding of the neurobehavioral consequences of these adolescent-related shifts in stress reactivity, continued study of developmental changes in stress-induced hormonal responses may shed light on the increased vulnerability to physical and psychological dysfunctions that often accompany a stressful adolescence. (C) 2016 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据