Retinal artery occlusion does not act as an independent marker of upcoming dementia: results from a Danish 20-year cohort study

Article Ophthalmology

Cardiovascular morbidity and all-cause mortality in patients with retinal vein occlusion: a Danish nationwide cohort study

Katrine Hartmund Frederiksen et al.

Summary: In a Danish study, it was found that patients with retinal vein occlusion (RVO) had a 13% increased risk of cardiovascular disease (CVD), but no increased risk of mortality. Similar risks of CVD were observed for branch and central RVO, but only central RVO patients exhibited increased mortality. Mortality was further increased after the introduction of angiostatic therapy and altered referral practices in 2011.

BRITISH JOURNAL OF OPHTHALMOLOGY (2023)

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Article Medicine, General & Internal

Lecanemab in Early Alzheimer's Disease

Christopher H. van Dyck et al.

Summary: Lecanemab, a humanized monoclonal antibody, reduced amyloid markers and showed improvement in cognition and function in early Alzheimer's disease patients. However, it also resulted in adverse events. Longer trials are needed to determine its efficacy and safety in early Alzheimer's disease.

NEW ENGLAND JOURNAL OF MEDICINE (2023)

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Article Neurosciences

Associations Between Retinal Artery/Vein Occlusions and Risk of Vascular Dementia

Cecilia S. Lee et al.

Summary: The study found that older patients who present with RAVO and carry the APOE epsilon 4 allele appear to be at higher risk for vascular dementia. There were no significant associations between RAVO and AD in either APOE group.

JOURNAL OF ALZHEIMERS DISEASE (2021)

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Article Ophthalmology

Relationship between Retinal Vascular Occlusions and Cognitive Dementia in a Large Cross-Sectional Cohort

Alison X. Chan et al.

Summary: Individuals with retinal vascular occlusions have a higher prevalence of dementia, but this association is mainly due to shared underlying risk factors such as older age and stroke, rather than a direct impact.

AMERICAN JOURNAL OF OPHTHALMOLOGY (2021)

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Article Ophthalmology