期刊
CHEMICAL SOCIETY REVIEWS
卷 44, 期 14, 页码 4953-4972出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cs00030k
关键词
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资金
- Ministry of Education, Culture, Sports, Science, and Technology, Japan [25620133, 25220207, 26102529, 26.794]
- CREST from JST
- Grants-in-Aid for Scientific Research [26102529, 15K12754] Funding Source: KAKEN
Fluorescence imaging techniques have been widely used to visualize biological molecules and phenomena. In particular, several studies on the development of small-molecule fluorescent probes have been carried out, because their fluorescence properties can be easily tuned by synthetic chemical modification. For this reason, various fluorescent probes have been developed for targeting biological components, such as proteins, peptides, amino acids, and ions, to the interior and exterior of cells. In this review, we cover advances in the development of 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY)-based fluorescent probes for biological studies over the past decade.
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