IgG4-related hypertrophic pachymeningitis with chronic subdural haematoma

Hypertrophic pachymeningitis is a rare disorder of the dura mater of the spine or brain. It can be caused by inflammatory, infective or neoplastic conditions or can be idiopathic. We report a man with hypertrophic pachymeningitis and bilateral chronic subdural haematoma caused by IgG4-related disease. We highlight the diagnostic challenges and discuss possible underlying mechanisms of subdural haematoma formation in inflammatory conditions. Isolated IgG4-related hypertrophic pachymeningitis with chronic subdural haematoma is very rare; previously reported cases have suggested a possible predilection for men in their sixth decade, presenting with headache as the dominant symptom. Given the rarity and complexity of the condition, it should be managed in a multidisciplinary team setting.

Automated summary

We report a rare case of hypertrophic pachymeningitis and bilateral chronic subdural haematoma caused by IgG4-related disease. The diagnostic challenges and possible underlying mechanisms of subdural haematoma formation in inflammatory conditions are discussed. Given the rarity and complexity of the condition, a multidisciplinary team approach is recommended for management.