期刊
NEURON
卷 89, 期 4, 页码 675-677出版社
CELL PRESS
DOI: 10.1016/j.neuron.2016.02.008
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资金
- NINDS NIH HHS [R00 NS087098] Funding Source: Medline
Motor impairments in Parkinson's disease are thought to result from hypoactivation of striatal projection neurons in the direct pathway. In this issue of Neuron, Parker et al. (2016) report that dopamine depletion selectively weakens thalamic but not cortical afferents onto these neurons, implicating the thalamus as playing a key role in Parkinsonian motor symptoms.
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