☆ 3.8 Article

DMSO arbitrated Oxidative Annulation Followed by Homologated N-Alkylation: Microwave-Assisted Efficient and Greener Approach to Access 3-(3-Oxo-3-arylpropyl) Quinazolinones

SYNOPEN (2023)

Copper-catalyzed three-component N-alkylation of quinazolinones and azoles

Chunlian Wang et al.

Summary: A Cu-catalyzed three-component N-alkylation coupling reaction using N-heteroarenes, methyl ketones, and DMPA as starting materials has been developed, leading to the synthesis of various functionalized N-heterocycles.

ORGANIC & BIOMOLECULAR CHEMISTRY (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

DMSO as a dual carbon synthon in one-pot tandem synthesis of N-alkylated quinazolinones from anthranilamides and acetophenones

Pushpendra Yadav et al.

Summary: A new method for the synthesis of N-alkylated quinazolinones has been developed using readily available starting materials and an oxidizing agent. This efficient and metal-free approach utilizes DMSO as a solvent and a dual carbon synthon, leading to environmentally benign synthesis of medicinally prevalent compounds.

NEW JOURNAL OF CHEMISTRY (2022)

添加到收藏夹

Article Chemistry, Applied

Sulfur-Promoted Synthesis of 2-Aroylquinazolin-4(3H)-ones by Oxidative Condensation of Anthranilamide and Acetophenones

Thanh Binh Nguyen et al.

ADVANCED SYNTHESIS & CATALYSIS (2019)

添加到收藏夹

Article Chemistry, Organic

Synthesis of 2,3-dihydroquinazolin-4(1H)-ones from anthranilamide and ketones over H zeolite in aqueous media

Krishna Sai Gajula et al.

SYNTHETIC COMMUNICATIONS (2018)

添加到收藏夹

Article Chemistry, Organic

Iodine Catalyzed Oxidative Synthesis of Quinazolin-4(3H)-ones and Pyrazolo[4,3-d]pyrimidin-7(6H)-ones via Amination of sp3 C-H Bond

Shabber Mohammed et al.

JOURNAL OF ORGANIC CHEMISTRY (2015)

添加到收藏夹

Article Chemistry, Organic

Direct One-Pot Synthesis of Luotonin F and Analogues via Rational Logical Design

Yan-ping Zhu et al.

ORGANIC LETTERS (2013)

添加到收藏夹

DMSO arbitrated Oxidative Annulation Followed by Homologated N-Alkylation: Microwave-Assisted Efficient and Greener Approach to Access 3-(3-Oxo-3-arylpropyl) Quinazolinones

相关参考文献

Copper-catalyzed three-component N-alkylation of quinazolinones and azoles

DMSO as a dual carbon synthon in one-pot tandem synthesis of N-alkylated quinazolinones from anthranilamides and acetophenones

Sulfur-Promoted Synthesis of 2-Aroylquinazolin-4(3H)-ones by Oxidative Condensation of Anthranilamide and Acetophenones

Synthesis of 2,3-dihydroquinazolin-4(1H)-ones from anthranilamide and ketones over H zeolite in aqueous media

Iodine Catalyzed Oxidative Synthesis of Quinazolin-4(3H)-ones and Pyrazolo[4,3-d]pyrimidin-7(6H)-ones via Amination of sp3 C-H Bond

Direct One-Pot Synthesis of Luotonin F and Analogues via Rational Logical Design

导出引文

分享论文