☆ 3.8 Article

Selection of consistent breath biomarkers of abnormal liver function using feature selection: a pilot study

HEALTH AND TECHNOLOGY (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Review Biochemistry & Molecular Biology

Breath volatile organic compounds (VOCs) as biomarkers for the diagnosis of pathological conditions: A review

Pedro Catala Moura et al.

Summary: The normal and abnormal/pathological status of physiological processes in the human organism can be characterized through Volatile Organic Compounds (VOCs) emitted in breath. These compounds have been recognized as valuable biomarkers for the rapid, accurate, non-invasive, and painless diagnosis of various diseases and health conditions. This study reviews the most promising results in the field of breath biomarkers and the common methods of detecting VOCs, while also providing a database of compounds for 16 different pathologies.

BIOMEDICAL JOURNAL (2023)

添加到收藏夹

Article Public, Environmental & Occupational Health

Variation in Laboratory Reports: Causes other than Laboratory Error

Santosh Pradhan et al.

Summary: The results of clinical laboratory tests are highly variable and inconsistent not only due to laboratory errors, but also because of preanalytical variation, biological variation, and analytical variation.

JOURNAL OF NEPAL MEDICAL ASSOCIATION (2022)

添加到收藏夹

Article Multidisciplinary Sciences

A pilot study for the prediction of liver function related scores using breath biomarkers and machine learning

Rakesh Kumar Patnaik et al.

Summary: This study proposes a method for early detection and progress monitoring of liver diseases using volatile organic compounds (VOCs) in exhaled breath as biomarkers. Machine learning is applied to predict scores for liver function diagnosis, and significant differences in breath profiles are found between liver patients and healthy volunteers.

SCIENTIFIC REPORTS (2022)

添加到收藏夹

Article Computer Science, Interdisciplinary Applications

Diagnosis of COVID-19 via acoustic analysis and artificial intelligence by monitoring breath sounds on smartphones

Zhiang Chen et al.

Summary: Scientific evidence suggests that acoustic analysis can be used as an indicator for diagnosing COVID-19. By analyzing breath sounds recorded on smartphones, researchers have discovered different patterns in both the time and frequency domains for patients with COVID-19. These patterns are utilized to diagnose the infection of COVID-19, employing statistical analysis, frequency domain analysis, and Mel-Frequency Cepstral Coefficients (MFCCs) in k-Nearest Neighbors (kNN) and Convolutional Neural Network (CNN) classifiers. Test results demonstrate that the CNN classifier achieves an impressive accuracy rate of over 97%, while kNN with optimized features achieves more than 85%. This paper also introduces optimization methods for feature selection and various metrics for performance evaluation. The high accuracy of the CNN model leads to its implementation in an Android app, providing a powerful tool for society to diagnose COVID-19 regardless of the availability of other medical resources. The initial medical test shows promising results, indicating the feasibility and effectiveness of the proposed method when compared to the lateral flow method.

JOURNAL OF BIOMEDICAL INFORMATICS (2022)

添加到收藏夹

Review Biochemistry & Molecular Biology

Insights into Molecular Structure of Pterins Suitable for Biomedical Applications

Andrey A. Buglak et al.

Summary: This review focuses on the quantum chemistry and photonics of pterins, providing a comprehensive overview of their electronic structure and potential applications in biomedicine. The study suggests that UV irradiation of pterins can affect enzymatic reactions and that the emission properties of pterins can be used in fluorescence diagnostics. The use of two-photon absorption and metal nanostructures is also proposed for pterin-related infrared therapy and spectroscopy detection of biomarkers.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

添加到收藏夹

Article Multidisciplinary Sciences

Development of a machine-learning algorithm to predict in-hospital cardiac arrest for emergency department patients using a nationwide database

Ji Hoon Kim et al.

Summary: In this study, a machine-learning model was developed using data obtained at the prehospital stage to predict in-hospital cardiac arrest in the emergency department. The model showed good performance and identified several important factors, such as oxygen supply, age, and oxygen saturation, that contribute to the prediction.

SCIENTIFIC REPORTS (2022)

添加到收藏夹

Review Immunology

The Gut-Liver Axis in Health and Disease: The Role of Gut Microbiota-Derived Signals in Liver Injury and Regeneration

Zhipeng Zheng et al.

Summary: Liver diseases often involve liver regeneration after injury, which can be influenced by changes in gut microbiota and signals through the gut-liver axis. Modulation of gut microbiota by antibiotics or probiotics impacts liver injury and regeneration. Microbial metabolites such as lipopolysaccharide and bile acids may play roles in these processes.

FRONTIERS IN IMMUNOLOGY (2021)

添加到收藏夹

Article Gastroenterology & Hepatology

Sodium Butyrate Supplementation Inhibits Hepatic Steatosis by Stimulating Liver Kinase B1 and Insulin-Induced Gene

Ze-Hua Zhao et al.

Summary: In this study, it was found that administration of NaB for 8 weeks in NAFLD mice enhances Insig activity while inhibiting lipogenic gene, and partially prevents hepatic steatosis through the activation of the LKB1-AMPK-Insig signaling pathway.

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2021)

添加到收藏夹

Article Multidisciplinary Sciences

International evaluation of an AI system for breast cancer screening

Scott Mayer McKinney et al.

NATURE (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Target Analysis of Volatile Organic Compounds in Exhaled Breath for Lung Cancer Discrimination from Other Pulmonary Diseases and Healthy Persons

Michalis Koureas et al.

METABOLITES (2020)

添加到收藏夹

Article Medicine, General & Internal

Comparison of Pteridine Normalization Methods in Urine for Detection of Bladder Cancer

Piotr Koslinski et al.

DIAGNOSTICS (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

N-Acetyl Cysteine Targets Hepatic Lipid Accumulation to Curb Oxidative Stress and Inflammation in NAFLD: A Comprehensive Analysis of the Literature

Phiwayinkosi Dludla et al.

ANTIOXIDANTS (2020)

添加到收藏夹

Article Neuroimaging

Stable biomarker identification for predicting schizophrenia in the human connectome

Leonardo Gutierrez-Gomez et al.

NEUROIMAGE-CLINICAL (2020)

添加到收藏夹

Article Surgery

Revisiting donor risk over two decades of single-center experience: More attention on the impact of overweight

Cheng-Maw Ho et al.

ASIAN JOURNAL OF SURGERY (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Ultra-High-Performance Liquid Chromatography-Tandem Mass Spectrometry Assay for Quantifying Fentanyl and 22 Analogs and Metabolites in Whole Blood, Urine, and Hair

Francesco Paolo Busardo et al.

FRONTIERS IN CHEMISTRY (2019)

添加到收藏夹

Editorial Material Gastroenterology & Hepatology

Exhaled breath analysis in hepatology: State-of-the-art and perspectives

Antonio De Vincentis et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2019)

添加到收藏夹

Article Biology

Early non-invasive detection of breast cancer using exhaled breath and urine analysis

Or Herman-Saffar et al.

COMPUTERS IN BIOLOGY AND MEDICINE (2018)

添加到收藏夹

Article Radiology, Nuclear Medicine & Medical Imaging

Machine learning algorithms for outcome prediction in (chemo)radiotherapy: An empirical comparison of classifiers

Timo M. Deist et al.

MEDICAL PHYSICS (2018)

添加到收藏夹

Article Sport Sciences

A pilot study comparing the metabolic profiles of elite-level athletes from different sporting disciplines

Fatima Al-Khelaifi et al.

SPORTS MEDICINE-OPEN (2018)

添加到收藏夹

Article Oncology

The Burden of Primary Liver Cancer and Underlying Etiologies From 1990 to 2015 at the Global, Regional, and National Level Results From the Global Burden of Disease Study 2015

Tomi Akinyemiju et al.

JAMA ONCOLOGY (2017)

添加到收藏夹

Article Medicine, Research & Experimental

Deep Learning Applications for Predicting Pharmacological Properties of Drugs and Drug Repurposing Using Transcriptomic Data

Alexander Aliper et al.

MOLECULAR PHARMACEUTICS (2016)

添加到收藏夹

Article Computer Science, Artificial Intelligence

Subtyping: What It Is and Its Role in Precision Medicine

Suchi Saria et al.

IEEE INTELLIGENT SYSTEMS (2015)

添加到收藏夹

Review Biochemistry & Molecular Biology

Oxidative Stress and Inflammation in Hepatic Diseases: Therapeutic Possibilities of N-Acetylcysteine

Kivia Queiroz de Andrade et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)

添加到收藏夹

Article Biochemistry & Molecular Biology

Differences in pteridine urinary levels in patients with malignant and benign ovarian tumors in comparison with healthy individuals

M. Zvarik et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2015)

添加到收藏夹

Review Biochemistry & Molecular Biology

Breath Analysis as a Potential and Non-Invasive Frontier in Disease Diagnosis: An Overview

Jorge Pereira et al.

METABOLITES (2015)

添加到收藏夹

Article Biochemical Research Methods

Breath analysis for in vivo detection of pathogens related to ventilator-associated pneumonia in intensive care patients: a prospective pilot study

Wojciech Filipiak et al.

JOURNAL OF BREATH RESEARCH (2015)

添加到收藏夹

Article Biochemistry & Molecular Biology

Coenzyme A and its derivatives: renaissance of a textbook classic

Frederica L. Theodoulou et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2014)

添加到收藏夹

Article Gastroenterology & Hepatology

Analysis of breath volatile organic compounds as a noninvasive tool to diagnose nonalcoholic fatty liver disease in children

Naim Alkhouri et al.

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY (2014)

添加到收藏夹

Review Biochemical Research Methods

A review of the volatiles from the healthy human body

B. de Lacy Costello et al.

JOURNAL OF BREATH RESEARCH (2014)

添加到收藏夹

Review Biochemistry & Molecular Biology

Glutathione synthesis

Shelly C. Lu

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2013)

添加到收藏夹

Article Mathematical & Computational Biology

Naive Bayes Classifier with Feature Selection to Identify Phage Virion Proteins

Peng-Mian Feng et al.

COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE (2013)

添加到收藏夹

Article Biochemistry & Molecular Biology

Widespread and Enzyme-independent N∈-Acetylation and N∈-Succinylation of Proteins in the Chemical Conditions of the Mitochondrial Matrix

Gregory R. Wagner et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

添加到收藏夹

Article Gastroenterology & Hepatology

Protective effect of N-acetylcysteine on antituberculosis drug-induced hepatotoxicity

Shadi Baniasadi et al.

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY (2010)

添加到收藏夹

Review Gastroenterology & Hepatology

Liver: An organ with predominant innate immunity

Bin Gao et al.

HEPATOLOGY (2008)

添加到收藏夹

Article Allergy

An electronic nose in the discrimination of patients with asthma and controls

Silvano Dragonieri et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2007)

添加到收藏夹

Article Biochemical Research Methods

Simultaneous determination of tetrabromobisphenol A, tetrachlorobisphenol A, bisphenol A and other halogenated analogues in sediment and sludge by high performance liquid chromatography-electrospray tandem mass spectrometry

SG Chu et al.

JOURNAL OF CHROMATOGRAPHY A (2005)

添加到收藏夹

Review Biochemistry & Molecular Biology

Coenzyme A: Back in action

R Leonardi et al.

PROGRESS IN LIPID RESEARCH (2005)

添加到收藏夹

Article Biochemistry & Molecular Biology

Breath alkanes as a marker of oxidative stress in different clinical conditions

E Aghdassi et al.

FREE RADICAL BIOLOGY AND MEDICINE (2000)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.