3.8 Review

Post-transplantation Lymphoproliferative Disorder (PTLD): In the Liver Transplant Recipient

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Hematology

Post-transplant lymphoproliferative disorder: Update on treatment and novel therapies

Suheil Albert Atallah-Yunes et al.

Summary: Post-transplant lymphoproliferative disorder (PTLD) is a rare and heterogeneous lymphoid proliferation caused by immunosuppression following organ transplant. Treatment of PTLD differs from immunocompetent patients due to its different pathobiology and higher risk of complications. This review provides an update on the treatment of PTLD, including the incorporation of more aggressive chemotherapy regimens and novel treatments, the role of EBV-cytotoxic T lymphocytes, and the potential challenges of CAR-T therapy and immune checkpoint inhibitors in this patient population.

BRITISH JOURNAL OF HAEMATOLOGY (2023)

Article Gastroenterology & Hepatology

Post-transplant Lymphoproliferative Disorders After Liver Transplantation: A Retrospective Cohort Study Including 1,954 Transplants

Tetsuya Tajima et al.

Summary: Post-transplant lymphoproliferative disorders (PTLDs) are life-threatening neoplasms that occur after organ transplantation. In this review of 1,954 liver transplants, 79 PTLD lesions were identified, affecting patient survival. Age ≥ 18 years at PTLD diagnosis, PS ≥ 2 at diagnosis, and monomorphic type were identified as independent prognostic factors for PTLD patients.

LIVER TRANSPLANTATION (2021)

Article Biophysics

Autologous stem cell transplantation for post-transplant lymphoproliferative disorders after solid organ transplantation: a retrospective analysis from the Lymphoma Working Party of the EBMT

Toby A. Eyre et al.

Summary: This retrospective analysis of 21 patients who underwent autoSCT for PTLD post solid organ transplant found that although autoSCT is feasible and potentially effective, it is associated with a high non-relapse mortality primarily driven by infectious toxicity. A multidisciplinary approach, expert microbiological input, and stringent patient selection are necessary to optimize outcomes.

BONE MARROW TRANSPLANTATION (2021)

Article Gastroenterology & Hepatology

Late-Onset Peripheral T-Cell Lymphoma Not Otherwise Specified in a Liver Transplant Recipient: A Rare Subtype of Posttransplant Lymphoproliferative Disorder

Jagadeesh Menon et al.

Summary: PTLD, a rare complication after liver transplant, commonly involves B-cell subtype associated with EBV infection, while T-cell subtype is even rarer. This case presents a 21-year-old patient with peripheral T-cell lymphoma associated with EBV infection, achieving remission after standard chemotherapy.

JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGY (2021)

Review Hematology

Post Transplant Lymphoproliferative Disorder

Devika Gupta et al.

INDIAN JOURNAL OF HEMATOLOGY AND BLOOD TRANSFUSION (2020)

Article Radiology, Nuclear Medicine & Medical Imaging

Posttransplant Lymphoproliferative Disorder in Children: A 360-degree Perspective

Eman Marie et al.

RADIOGRAPHICS (2020)

Article Medicine, General & Internal

Post-transplantation lymphoproliferative disease in pediatric liver recipients in Taiwan

Chien-Ting Hsu et al.

JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION (2019)

Review Oncology

Post-transplant Epstein-Barr Virus-Related Lymphoproliferative Disorder: A Case Report and Review of Literature

Vasu Babu Goli et al.

INDIAN JOURNAL OF MEDICAL AND PAEDIATRIC ONCOLOGY (2019)

Review Medicine, General & Internal

Post-Transplantation Lymphoproliferative Disorders in Adults

Daan Dierickx et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Gastroenterology & Hepatology

EASL Clinical Practice Guidelines: Liver transplantation

Patrizia Burra et al.

JOURNAL OF HEPATOLOGY (2016)

Article Surgery

Epstein-Barr Virus and Posttransplant Lymphoproliferative Disorder in Solid Organ Transplantation

U. D. Allen et al.

AMERICAN JOURNAL OF TRANSPLANTATION (2013)

Article Hematology

Lymphomas differ in their dependence on Epstein-Barr virus

David T. Vereide et al.

Review Transplantation

Posttransplant lymphoproliferative disease following liver transplantation

Kala Y. Kamdar et al.

CURRENT OPINION IN ORGAN TRANSPLANTATION (2011)

Article Cardiac & Cardiovascular Systems

Role of immunosuppression regimen in post-transplant lymphoproliferative disorder in pediatric heart transplant patients

Jeffrey D. Dayton et al.

JOURNAL OF HEART AND LUNG TRANSPLANTATION (2011)

Review Oncology

Post-transplant lymphoproliferative disorders (PTLD) after solid organ transplantation

AL Taylor et al.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2005)