Elderly Onset of Functional Motor Disorders: Clinical Correlates from the Italian Registry

Review Clinical Neurology

Functional movement disorder gender, age and phenotype study: a systematic review and individual patient meta-analysis of 4905 cases

Sarah C. Lidstone et al.

Summary: Functional movement disorder (FMD) is a common manifestation of functional neurological disorder with diverse phenotypes. This meta-analysis examined the relationship between age at onset, phenotype, and gender in FMD. The study found that women had an earlier age of onset than men, and mixed FMD, tremor, and weakness were the most common phenotypes. The data supports the concept of both grouping FMD as a unitary disorder and splitting it into individual phenotypes.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2022)

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Article Clinical Neurology

Functional motor disorders associated with other neurological diseases: Beyond the boundaries of organic neurology

Michele Tinazzi et al.

Summary: This study found that comorbid functional motor disorders with other neurological diseases are common, usually appearing after the diagnosis of another neurological disease. Patients with comorbid FMDs are typically older and have tremor, non-neurological comorbidities, etc. The importance of early diagnosis of FMDs is highlighted due to the frequent association with other neurological and non-neurological diseases.

EUROPEAN JOURNAL OF NEUROLOGY (2021)

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Article Clinical Neurology

International online survey of 1048 individuals with functional neurological disorder

Matthew Butler et al.

Summary: This large-scale international study on Functional Neurological Disorders (FND) patient experiences highlighted that FND patients typically have high levels of multiple symptom comorbidities and distress. The study also supported the clinical significance of associated physical symptoms in FND patients, and most respondents preferred to conceptualize the disorder as one at the interface of mind and brain. The need for a broad approach to this poorly served patient group was emphasized.

EUROPEAN JOURNAL OF NEUROLOGY (2021)

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Article Clinical Neurology