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Complete genome sequence of the archetype bile acid 7a-dehydroxylating bacterium, Clostridium scindens VPI12708, isolated from human feces, circa 1980

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AMER SOC MICROBIOLOGY
DOI: 10.1128/MRA.00029-23

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Clostridium scindens; 7 & alpha;-dehydroxylating bacteria; genome sequencing; genome assembly; bile acid

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Clostridium scindens strain VPI12708 is used as a model organism to study bile acid 7a-dehydroxylating pathways. The closed circular genome of C. scindens VPI12708, with 3,983,052 bp and 47.59% G + C, was obtained by PacBio sequencing. A total of 3,707 coding DNA sequences are predicted in the genome.
Clostridium scindens strain VPI12708 serves as model organism to study bile acid 7a-dehydroxylating pathways. The closed circular genome of C. scindens VPI12708 was obtained by PacBio sequencing. The genome is composed of 3,983,052 bp, with 47.59% G + C, and 3,707 coding DNA sequences are predicted.

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