4.5 Review

Potential role of Chinese medicine nanoparticles to treat coronary artery disease

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Biochemistry & Molecular Biology

Tissue Engineering and Targeted Drug Delivery in Cardiovascular Disease: The Role of Polymer Nanocarrier for Statin Therapy

Nunzio Montelione et al.

Summary: Atherosclerosis-related coronary artery disease (CAD) is the leading cause of mortality and morbidity worldwide. Statins have proved to be the most effective treatment, but there are limitations related to administration and side effects. Polymers and nanoparticles can enhance the effect of statins by increasing bioavailability and target specificity. Poly-lactic-co-glycolic acid (PLGA) is the most promising drug delivery system.

BIOMEDICINES (2023)

Article Pharmacology & Pharmacy

Application of chitosan/alginate nanoparticle in oral drug delivery systems: prospects and challenges

Li Shangyong et al.

Summary: Oral drug delivery systems have advantages of simplicity and minimal side effects, making them suitable for colon-targeted therapy. Chitosan/alginate nanoparticles (CANPs) show potential in the treatment of intestinal diseases due to their strong electrostatic interaction and intestinal mucosal adhesion.

DRUG DELIVERY (2022)

Article Peripheral Vascular Disease

Pitavastatin-Incorporated Nanoparticles for Chronic Limb Threatening Ischemia: A Phase I/IIa Clinical Trial

Takuya Matsumoto et al.

Summary: This study assessed the clinical trial results of pitavastatin-incorporated nanoparticles in patients with chronic limb threatening ischemia (CLTI). The results showed that intramuscular administration of NK-104-NP was safe and well tolerated and resulted in improvements in limb function.

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS (2022)

Article Plant Sciences

Evidence construction of baicalin for treating myocardial ischemia diseases: A preclinical meta-analysis

Sihan Hu et al.

Summary: Baicalin exhibits positive effects on myocardial ischemia diseases, achieved by regulating key pathological indicators and various signaling pathways. In animal models of myocardial ischemia, reperfusion injury, and myocardial infarction, baicalin can reduce myocardial infarction size, improve cardiac pathological condition, and enhance heart function indicators.

PHYTOMEDICINE (2022)

Review Chemistry, Analytical

Analytical characterization of liposomes and other lipid nanoparticles for drug delivery

Yuchen Fan et al.

Summary: Lipid nanoparticles, including liposomes and lipid/nucleic acid complexed nanoparticles, have shown success in the pharmaceutical industry due to stable drug loading, extended pharmacokinetics, reduced off-target side effects, and enhanced delivery efficiency to disease targets. Analytical characterization is crucial for drug design, formulation development, and quality control.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2021)

Article Endocrinology & Metabolism

Curcumin Nanomicelle Improves Lipid Profile, Stress Oxidative Factors and Inflammatory Markers in Patients Undergoing Coronary Elective An- gioplasty; A Randomized Clinical Trial

Bijan Helli et al.

Summary: This study found that both curcumin and nano-curcumin have significant effects on improving lipid profiles, oxidative stress, and inflammatory factors related to heart in patients. Nano-curcumin showed better efficacy than curcumin in certain indicators.

ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS (2021)

Review Pharmacology & Pharmacy

Effects of Puerarin on the Prevention and Treatment of Cardiovascular Diseases

Yan-Xi Zhou et al.

Summary: Puerarin, derived from Pueraria lobata, is a pharmacologically active component widely used in the treatment of cardiovascular diseases. This review systematically analyzes its preclinical investigations and clinical trials in CVD, discussing its potential molecular targets and therapeutic effects.

FRONTIERS IN PHARMACOLOGY (2021)

Article Oncology

Phase 3 Trial Comparing Nanoparticle Albumin-Bound Paclitaxel With Docetaxel for Previously Treated Advanced NSCLC

Yasuto Yoneshima et al.

Summary: The study evaluated the efficacy and safety of nanoparticle albumin-bound paclitaxel in previously treated advanced NSCLC patients, showing noninferiority in overall survival compared to docetaxel. Furthermore, nab-paclitaxel demonstrated a higher objective response rate and longer progression-free survival.

JOURNAL OF THORACIC ONCOLOGY (2021)

Article Medicine, General & Internal

Myocardial protective effect of intracoronary administration of nicorandil and alprostadil via targeted perfusion microcatheter in patients undergoing elective percutaneous coronary intervention A randomized controlled trial

Weifeng Zhang et al.

Summary: The study evaluated the efficacy of nicorandil and alprostadil on myocardial protection in patients undergoing elective PCI. Results showed that both nicorandil and alprostadil were more effective in improving myocardial perfusion in these patients compared to nitroglycerin.

MEDICINE (2021)

Review Medicine, Research & Experimental

Pharmacological properties and underlying mechanisms of curcumin and prospects in medicinal potential

Yaw-Syan Fu et al.

Summary: Curcumin, a natural compound isolated from ginger plant, has demonstrated antiviral, antimicrobial, anti-tumor, lipid-lowering, blood glucose-reducing, antioxidant properties, as well as activities against various chronic diseases. Recent evidence reveals curcuminoids may have potential applications in medical problems, particularly during the COVID-19 pandemic.

BIOMEDICINE & PHARMACOTHERAPY (2021)

Review Biochemistry & Molecular Biology

Current opinion on the pharmacogenomics of paclitaxel-induced toxicity

Zeina N. Al-Mahayri et al.

Summary: Paclitaxel is a commonly used chemotherapeutic agent with notable efficacy in various types of cancer, however it is associated with toxicities such as neurotoxicity. Studies have explored mechanisms and risk factors of paclitaxel-induced toxicities, with promising candidates found in genes related to neuro-sensitivity for future research. Further investigation into toxicity development mechanisms and personal vulnerability factors is needed to enhance understanding and management of paclitaxel-associated toxicities.

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2021)

Article Pharmacology & Pharmacy

Acute myocardial infarction therapy: in vitro and in vivo evaluation of atrial natriuretic peptide and triphenylphosphonium dual ligands modified, baicalin-loaded nanoparticulate system

Jie Wang et al.

Summary: This study aimed to investigate the protective effect of baicalin (BA) and puerarin (PU) against acute MI rat models using a co-loaded nanoparticulate system. The dual ligands modified LPNs showed significantly improved therapeutic efficiency compared to other systems, making them a promising system for efficient delivery of cardiovascular drugs for the treatment of cardiovascular diseases.

DRUG DELIVERY (2021)

Article Health Care Sciences & Services

Effects of alprostadil combined with tanshinone Ila injection on microcirculation disorder, outcomes, and cardiac function in AMI patients after PCI

Yang Lu et al.

Summary: The combination of alprostadil and tanshinone IIa injection can effectively improve cardiac function, reduce the occurrence of MACEs, and is recommended for AMI patients after PCI.

ANNALS OF PALLIATIVE MEDICINE (2021)

Editorial Material Pharmacology & Pharmacy

Nanomedicine-based approaches for improved delivery of phyto-therapeutics for cancer therapy

Dina A. Hafez et al.

EXPERT OPINION ON DRUG DELIVERY (2020)

Review Pharmacology & Pharmacy

An overview of active and passive targeting strategies to improve the nanocarriers efficiency to tumour sites

Mohamed F. Attia et al.

JOURNAL OF PHARMACY AND PHARMACOLOGY (2019)

Review Pharmacology & Pharmacy

Cardiovascular therapies utilizing targeted delivery of nanomedicines and aptamers

Kei Xian Tan et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)

Review Biochemistry & Molecular Biology

Recent Advances in Treatment of Coronary Artery Disease: Role of Science and Technology

Eswar Kandaswamy et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Article Cardiac & Cardiovascular Systems

Regression of Atherosclerotic Plaques of Cholesterol-Fed Rabbits by Combined Chemotherapy With Paclitaxel and Methotrexate Carried in Lipid Core Nanoparticles

Fernando L. T. Gomes et al.

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS (2018)

Review Plant Sciences

Micro-/nano-sized delivery systems of ginsenosides for improved systemic bioavailability

Hyeongmin Kim et al.

JOURNAL OF GINSENG RESEARCH (2018)

Review Nanoscience & Nanotechnology

The use of nanotechnology in cardiovascular disease

Meera Chandarana et al.

APPLIED NANOSCIENCE (2018)

Article Pharmacology & Pharmacy

Polyethylene-glycol-coated gold nanoparticles improve cardiac function after myocardial infarction in mice

Aiju Tian et al.

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2018)

Article Chemistry, Physical

Thrombolysis Enhancing by Magnetic Manipulation of Fe3O4 Nanoparticles

Qian Li et al.

MATERIALS (2018)

Review Cardiac & Cardiovascular Systems

Nanoparticle-mediated drug delivery system for atherosclerotic cardiovascular disease

Tetsuya Matoba et al.

JOURNAL OF CARDIOLOGY (2017)

Review Chemistry, Multidisciplinary

Nanomaterials for cancer therapies

Qing Zhou et al.

NANOTECHNOLOGY REVIEWS (2017)

Review Cardiac & Cardiovascular Systems

Nanomedicine applied to cardiovascular diseases: latest developments

Virna Margarita Martin Gimenez et al.

THERAPEUTIC ADVANCES IN CARDIOVASCULAR DISEASE (2017)

Article Nanoscience & Nanotechnology

Prednisolone-containing liposomes accumulate in human atherosclerotic macrophages upon intravenous administration

Fleur M. van der Valk et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2015)

Review Biotechnology & Applied Microbiology

Stimuli-sensitive Systems-an emerging delivery system for drugs

Ankur Bhardwaj et al.

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY (2015)

Review Medicine, General & Internal

Drug-targeting methodologies with applications: A review

Clement Kleinstreuer et al.

WORLD JOURNAL OF CLINICAL CASES (2014)

Review Pharmacology & Pharmacy

Radix Puerariae: An overview of Its Chemistry, Pharmacology, Pharmacokinetics, and Clinical Use

Zhen Zhang et al.

JOURNAL OF CLINICAL PHARMACOLOGY (2013)

Review Chemistry, Multidisciplinary

PLGA-based nanoparticles: An overview of biomedical applications

Fabienne Danhier et al.

JOURNAL OF CONTROLLED RELEASE (2012)

Review Pharmacology & Pharmacy

Physical and Chemical Strategies for Therapeutic Delivery by Using Polymeric Nanoparticles

Jose M. Morachis et al.

PHARMACOLOGICAL REVIEWS (2012)