期刊
ADVANCED SYNTHESIS & CATALYSIS
卷 357, 期 11, 页码 2464-2468出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201500261
关键词
aryltrifluoromethylation; copper; diastereoselectivity; regioselectivity; Togni's reagent
资金
- National Natural Science Foundation of China [21132003, 21421062, 21372131]
- Specialized Research Fund for the Doctoral Program of Higher Education [20130031110017]
- 111 Project of Ministry of Education of China [B06005]
A method for copper-catalyzed aryltrifluoromethylation of N-phenylcinnamamides is reported. This method provides a straightforward route to a variety of CF3-containing 3,4-dihydroquinolin-2(1H)-ones with excellent regioselectivity and diastereoselectivity.
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