相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Histone variants and chromatin structure, update of advances
Vladyslava Sokolova et al.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2023)
PRDM16 Is a Compact Myocardium-Enriched Transcription Factor Required to Maintain Compact Myocardial Cardiomyocyte Identity in Left Ventricle
Tongbin Wu et al.
CIRCULATION (2022)
Pharmacological or genetic inhibition of hypoxia signaling attenuates oncogenic RAS-induced cancer phenotypes
Jun-yi Zhu et al.
DISEASE MODELS & MECHANISMS (2022)
Long noncoding RNA NEAT1 promotes cardiac fibrosis in heart failure through increased recruitment of EZH2 to the Smad7 promoter region
Zhuowang Ge et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2022)
Prdm6 controls heart development by regulating neural crest cell differentiation and
Lingjuan Hong et al.
JCI INSIGHT (2022)
Epigenetics as conductor in orchestra of pluripotent states
Ishita Baral et al.
CELL AND TISSUE RESEARCH (2022)
The landscape of histone modifications in epigenomics since 2020
Milad Shirvaliloo
EPIGENOMICS (2022)
Chromatin accessibility: methods, mechanisms, and biological insights
Andres R. Mansisidor et al.
NUCLEUS (2022)
Histones and their chaperones: Adaptive remodelers of an ever-changing chromatinic landscape
Karla Torres-Arciga et al.
FRONTIERS IN GENETICS (2022)
Lpt, trr, and Hcf regulate histone mono- and dimethylation that are essential for Drosophila heart development
Wen Huang et al.
DEVELOPMENTAL BIOLOGY (2022)
SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis
Jun-yi Zhu et al.
COMMUNICATIONS BIOLOGY (2022)
Germline variants inHEY2functional domains lead to congenital heart defects and thoracic aortic aneurysms
Eva S. van Walree et al.
GENETICS IN MEDICINE (2021)
Expanding the genotypic and phenotypic spectrum in a diverse cohort of 104 individuals with Wiedemann-Steiner syndrome
Sarah E. Sheppard et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2021)
Loss-of-function and missense variants in NSD2 cause decreased methylation activity and are associated with a distinct developmental phenotype
Paolo Zanoni et al.
GENETICS IN MEDICINE (2021)
Smyd1 is essential for myosin expression and sarcomere organization in craniofacial, extraocular, and cardiac muscles
Shuang Jiao et al.
JOURNAL OF GENETICS AND GENOMICS (2021)
Elevated EZH2 in ischemic heart disease epigenetically mediates suppression of NaV1.5 expression
Limei Zhao et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2021)
Functional analysis of SARS-CoV-2 proteins in Drosophila identifies Orf6-induced pathogenic effects with Selinexor as an effective treatment
Jun-yi Zhu et al.
CELL AND BIOSCIENCE (2021)
Histone Lysine Methyltransferase SETD2 Regulates Coronary Vascular Development in Embryonic Mouse Hearts
Fengling Chen et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
Smyd1 Orchestrates Early Heart Development Through Positive and Negative Gene Regulation
Zhen Wang et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
Prenatal Genetic Diagnosis in Three Fetuses With Left Heart Hypoplasia (LHH) From Three Unrelated Families
Sukun Luo et al.
FRONTIERS IN CARDIOVASCULAR MEDICINE (2021)
Myofibroblast Deficiency of LSD1 Alleviates TAC-Induced Heart Failure
Jin-Ling Huo et al.
CIRCULATION RESEARCH (2021)
EZH2 as an Epigenetic Regulator of Cardiovascular Development and Diseases
Jia-Li Yuan et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2021)
The role of demethylases in cardiac development and disease
Kathryn Davis et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2021)
H3K9me2 regulates early transcription factors to promote mesenchymal stem-cell differentiation into cardiomyocytes
Xiaolin Sun et al.
MOLECULAR MEDICINE REPORTS (2021)
H3K36 methyltransferase NSD1 regulates chondrocyte differentiation for skeletal development and fracture repair
Rui Shao et al.
BONE RESEARCH (2021)
Contribution of single-gene defects to congenital cardiac left-sided lesions in the prenatal setting
H. Sun et al.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY (2020)
Cardiomyopathy due to PRDM16 mutation: First description of a fetal presentation, with possible modifier genes
Geoffroy Delplancq et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS (2020)
Cardiac-specific inactivation of Prdm16 effects cardiac conduction abnormalities and cardiomyopathy-associated phenotypes
Jeong Min Nam et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2020)
A restricted spectrum of missense KMT2D variants cause a multiple malformations disorder distinct from Kabuki syndrome
Sara Cuvertino et al.
GENETICS IN MEDICINE (2020)
De novo damaging variants associated with congenital heart diseases contribute to the connectome
Weizhen Ji et al.
SCIENTIFIC REPORTS (2020)
Identification of novel candidate genes in heterotaxy syndrome patients with congenital heart diseases by whole exome sequencing
Shuzhang Liang et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2020)
Transcriptional regulation by methyltransferases and their role in the heart: highlighting novel emerging functionality
Marta W. Szulik et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2020)
Inhibition of EZH2 attenuates coronary heart disease by interacting with microRNA-22 to regulate the TXNIP/nuclear factor-κB pathway
Yong Liu et al.
EXPERIMENTAL PHYSIOLOGY (2020)
Prdm16 Deficiency Leads to Age-Dependent Cardiac Hypertrophy, Adverse Remodeling, Mitochondrial Dysfunction, and Heart Failure
Dasan Mary Cibi et al.
CELL REPORTS (2020)
Defective sarcomere assembly in smyd1a and smyd1b zebrafish mutants
Mengxin Cai et al.
FASEB JOURNAL (2019)
The expanding landscape of 'oncohistone' mutations in human cancers
Benjamin A. Nacev et al.
NATURE (2019)
Loss of function of Kmt2d, a gene mutated in Kabuki syndrome, affects heart development in Xenopus laevis
Janina Schwenty-Lara et al.
DEVELOPMENTAL DYNAMICS (2019)
PDGFR-β Signaling Regulates Cardiomyocyte Proliferation and Myocardial Regeneration
Zhang Yue et al.
CELL REPORTS (2019)
Inhibition of Notch signaling rescues cardiovascular development in Kabuki Syndrome
Maria de los Angeles Serrano et al.
PLOS BIOLOGY (2019)
EZH2 as a novel therapeutic target for atrial fibrosis and atrial fibrillation
Shuai Song et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2019)
Histone lysine methyltransferases in biology and disease
Dylan Husmann et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2019)
Kindlin-2 suppresses transcription factor GATA4 through interaction with SUV39H1 to attenuate hypertrophy
Lihua Qi et al.
CELL DEATH & DISEASE (2019)
Regulatory Factor X1 Downregulation Contributes to Monocyte Chemoattractant Protein-1 Overexpression in CD14+Monocytes via Epigenetic Mechanisms in Coronary Heart Disease
Sujie Jia et al.
FRONTIERS IN GENETICS (2019)
NSD2 promotes ventricular remodelling mediated by the regulation of H3K36me2
Xue-liang Zhou et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2019)
The timeline of epigenetic drug discovery: from reality to dreams
A. Ganesan et al.
CLINICAL EPIGENETICS (2019)
Histone Lysine Methylases and Demethylases in the Landscape of Human Developmental Disorders
Victor Faundes et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2018)
The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia
Eytan M. Stein et al.
BLOOD (2018)
SETD7 Drives Cardiac Lineage Commitment through Stage-Specific Transcriptional Activation
Jaecheol Lee et al.
CELL STEM CELL (2018)
Repressive histone methylation regulates cardiac myocyte cell cycle exit
Danny El-Nachef et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2018)
Enhancer of zeste homolog 2 (EZH2) inhibitors
Nitya Gulati et al.
LEUKEMIA & LYMPHOMA (2018)
PRDM9 and Its Role in Genetic Recombination
Kenneth Paigen et al.
TRENDS IN GENETICS (2018)
Histone methyltransferase Smyd1 regulates mitochondrial energetics in the heart
Junco S. Warren et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure
Mary E. Sweet et al.
BMC GENOMICS (2018)
A Screening Approach to Identify Clinically Actionable Variants Causing Congenital Heart Disease in Exome Data
Justin O. Szot et al.
CIRCULATION-GENOMIC AND PRECISION MEDICINE (2018)
A Personalized Model of COQ2 Nephropathy Rescued by the Wild-Type COQ2 Allele or Dietary Coenzyme Q10 Supplementation
Jun-yi Zhu et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2017)
The Histone Methyltransferase Mixed Lineage Leukemia (MLL) 3 May Play a Potential Role in Clinical Dilated Cardiomyopathy
Ding-Sheng Jiang et al.
MOLECULAR MEDICINE (2017)
Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands
Sheng Chih Jin et al.
NATURE GENETICS (2017)
Genome-wide association and pathway analysis of left ventricular function after anthracycline exposure in adults
Quinn S. Wells et al.
PHARMACOGENETICS AND GENOMICS (2017)
Mrg15 stimulates Ash1 H3K36 methyltransferase activity and facilitates Ash1 Trithorax group protein function in Drosophila
Chang Huang et al.
NATURE COMMUNICATIONS (2017)
Whole exome sequencing in 342 congenital cardiac left sided lesion cases reveals extensive genetic heterogeneity and complex inheritance patterns
Alexander H. Li et al.
GENOME MEDICINE (2017)
Functional convergence of histone methyltransferases EHMT1 and KMT2C involved in intellectual disability and autism spectrum disorder
Tom S. Koemans et al.
PLOS GENETICS (2017)
High throughput in vivo functional validation of candidate congenital heart disease genes in Drosophila
Jun-yi Zhu et al.
ELIFE (2017)
Histone Methyltransferase G9a Is Required for Cardiomyocyte Homeostasis and Hypertrophy
Roberto Papait et al.
CIRCULATION (2017)
Congenital heart defects in molecularly proven Kabuki syndrome patients
Maria Cristina Digilio et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2017)
Histone Modification Is Correlated With Reverse Left Ventricular Remodeling in Nonischemic Dilated Cardiomyopathy
Emiko Ito et al.
ANNALS OF THORACIC SURGERY (2017)
Diagnostic Yield of Whole Exome Sequencing in Pediatric Dilated Cardiomyopathy
Pamela A. Long et al.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE (2017)
Divergent Requirements for EZH1 in Heart Development Versus Regeneration
Shanshan Ai et al.
CIRCULATION RESEARCH (2017)
Histone demethylases Kdm6ba and Kdm6bb redundantly promote cardiomyocyte proliferation during zebrafish heart ventricle maturation
Alexander A. Akerberg et al.
DEVELOPMENTAL BIOLOGY (2017)
Writing, erasing and reading histone lysine methylations
Kwangbeom Hyun et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2017)
Delineation of clinical features in Wiedemann-Steiner syndrome caused by KMT2A mutations
N. Miyake et al.
CLINICAL GENETICS (2016)
The chromatin-binding protein Smyd1 restricts adult mammalian heart growth
Sarah Franklin et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2016)
G9a histone methyltransferase inhibitor BIX01294 promotes expansion of adult cardiac progenitor cells without changing their phenotype or differentiation potential
K. Kaur et al.
CELL PROLIFERATION (2016)
KMT2D regulates specific programs in heart development via histone H3 lysine 4 di-methylation
Siang-Yun Ang et al.
DEVELOPMENT (2016)
ASH1L Links Histone H3 Lysine 36 Dimethylation to MLL Leukemia
Li Zhu et al.
CANCER DISCOVERY (2016)
De Novo and Rare Variants at Multiple Loci Support the Oligogenic Origins of Atrioventricular Septal Heart Defects
James R. Priest et al.
PLOS GENETICS (2016)
DOT1L-mediated H3K79me2 modification critically regulates gene expression during cardiomyocyte differentiation
P. Cattaneo et al.
CELL DEATH AND DIFFERENTIATION (2016)
The histone demethylase PHF8 represses cardiac hypertrophy upon pressure overload
Xiaoqian Liu et al.
EXPERIMENTAL CELL RESEARCH (2015)
RNA-Seq identifies novel myocardial gene expression signatures of heart failure
Yichuan Liu et al.
GENOMICS (2015)
Kabuki syndrome genes KMT2D and KDM6A: functional analyses demonstrate critical roles in craniofacial, heart and brain development
Peter M. Van Laarhoven et al.
HUMAN MOLECULAR GENETICS (2015)
Proper Activity of Histone H3 Lysine 4 (H3K4) Methyltransferase Is Required for Morphogenesis during Zebrafish Cardiogenesis
Jun-Dae Kim et al.
MOLECULES AND CELLS (2015)
Smyd1 Facilitates Heart Development by Antagonizing Oxidative and ER Stress Responses
Tara L. Rasmussen et al.
PLOS ONE (2015)
De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies
Jason Homsy et al.
SCIENCE (2015)
Histone methylations in heart development, congenital and adult heart diseases
Qing-Jun Zhang et al.
EPIGENOMICS (2015)
Deep RNA Sequencing Reveals Dynamic Regulation of Myocardial Noncoding RNAs in Failing Human Heart and Remodeling With Mechanical Circulatory Support
Kai-Chien Yang et al.
CIRCULATION (2014)
Identification of three novel genetic variations associated with electrocardiographic traits (QRS duration and PR interval) in East Asians
Kyung-Won Hong et al.
HUMAN MOLECULAR GENETICS (2014)
Mice Carrying a Hypomorphic Evi1 Allele Are Embryonic Viable but Exhibit Severe Congenital Heart Defects
Emilie A. Bard-Chapeau et al.
PLOS ONE (2014)
Six1 is down-regulated in end-stage human dilated cardiomyopathy independently of Ezh2
Anika Tschirner et al.
ESC HEART FAILURE (2014)
Fine Mapping of the 1p36 Deletion Syndrome Identifies Mutation of PRDM16 as a Cause of Cardiomyopathy
Anne-Karin Arndt et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2013)
De novo mutations in histone-modifying genes in congenital heart disease
Samir Zaidi et al.
NATURE (2013)
De Novo Mutations in MLL Cause Wiedemann-Steiner Syndrome
Wendy D. Jones et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2012)
A Temporal Chromatin Signature in Human Embryonic Stem Cells Identifies Regulators of Cardiac Development
Sharon L. Paige et al.
CELL (2012)
Dynamic and Coordinated Epigenetic Regulation of Developmental Transitions in the Cardiac Lineage
Joseph A. Wamstad et al.
CELL (2012)
Polycomb Repressive Complex 2 Regulates Normal Development of the Mouse Heart
Aibin He et al.
CIRCULATION RESEARCH (2012)
Jarid2 (Jumonji, AT Rich Interactive Domain 2) Regulates NOTCH1 Expression via Histone Modification in the Developing Heart
Matthew R. Mysliwiec et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis
Paul Delgado-Olguin et al.
NATURE GENETICS (2012)
Molecular mechanisms and potential functions of histone demethylases
Susanne Marije Kooistra et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Conditional Ablation of Ezh2 in Murine Hearts Reveals Its Essential Roles in Endocardial Cushion Formation, Cardiomyocyte Proliferation and Survival
Li Chen et al.
PLOS ONE (2012)
Substrate and product specificities of SET domain methyltransferases
Paul A. Del Rizzo et al.
EPIGENETICS (2011)
DOT1L regulates dystrophin expression and is critical for cardiac function
Anh T. Nguyen et al.
GENES & DEVELOPMENT (2011)
The histone methyltransferase Set7/9 promotes myoblast differentiation and myofibril assembly
Yazhong Tao et al.
JOURNAL OF CELL BIOLOGY (2011)
Uncovering the Human Methyltransferasome
Tanya C. Petrossian et al.
MOLECULAR & CELLULAR PROTEOMICS (2011)
NSD2 Links Dimethylation of Histone H3 at Lysine 36 to Oncogenic Programming
Alex J. Kuo et al.
MOLECULAR CELL (2011)
Smyd3 Is Required for the Development of Cardiac and Skeletal Muscle in Zebrafish
Tomoaki Fujii et al.
PLOS ONE (2011)
Update on Kleefstra Syndrome
M. H. Willemsen et al.
MOLECULAR SYNDROMOLOGY (2011)
The variations of BOP gene in hypertrophic cardiomyopathy
Neslihan Abaci et al.
ANATOLIAN JOURNAL OF CARDIOLOGY (2010)
Cardiac Deletion of Smyd2 Is Dispensable for Mouse Heart Development
Florian Diehl et al.
PLOS ONE (2010)
Role for the nuclear receptor-binding SET domain protein 1 (NSD1) methyltransferase in coordinating lysine 36 methylation at histone 3 with RNA polymerase II function
Agda Karina Lucio-Eterovic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
The Target of the NSD Family of Histone Lysine Methyltransferases Depends on the Nature of the Substrate
Yan Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome
Keisuke Nimura et al.
NATURE (2009)
PRDM6 is enriched in vascular precursors during development and inhibits endothelial cell proliferation, survival, and differentiation
Yaxu Wu et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2008)
Genome-Wide Survey and Developmental Expression Mapping of Zebrafish SET Domain-Containing Genes
Xiao-Jian Sun et al.
PLOS ONE (2008)
Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation
John W. Edmunds et al.
EMBO JOURNAL (2008)
Sotos syndrome
Genevieve Baujat et al.
ORPHANET JOURNAL OF RARE DISEASES (2007)
Trithorax-group protein ASH1 methylates histone H3 lysine 36
Yujro Tanaka et al.
GENE (2007)
Chromatin modifications and their function
Tony Kouzarides
CELL (2007)
SmyD1, a histone methyltransferase, is required for myofibril organization and muscle contraction in zebrafish embryos
XG Tan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Mutation analysis of the NSD1 gene in a group of 59 patients with congenital overgrowth
M Cecconi et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2005)
The etiology of Wolf-Hirschhorn syndrome
AD Bergemann et al.
TRENDS IN GENETICS (2005)
The SET-domain protein superfamily: protein lysine methyltransferases
SC Dillon et al.
GENOME BIOLOGY (2005)
Hallmarks of ion channel gene expression in end-stage heart failure
J Borlak et al.
FASEB JOURNAL (2003)
Mouse gridlock:: No aortic coarctation or deficiency, but fatal cardiac defects in Hey2 -/- mice
M Gessler et al.
CURRENT BIOLOGY (2002)
Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis
PD Gottlieb et al.
NATURE GENETICS (2002)
Purification and functional characterization of a histone H3-lysine 4-specific methyltransferase
HB Wang et al.
MOLECULAR CELL (2001)
The Arabidopsis thaliana genome contains at least 29 active genes encoding SET domain proteins that can be assigned to four evolutionarily conserved classes
LO Baumbusch et al.
NUCLEIC ACIDS RESEARCH (2001)
分享论文
