☆ 4.7 Article

Ultrasonic Plasticization Microinjection Precision Molding of Polypropylene Microneedle Arrays

ACS APPLIED POLYMER MATERIALS (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Materials Science, Characterization & Testing

Plastic rod as a promising feed material for enhanced performance of ultrasonic plasticization microinjection molding: Plasticization rate, mechanical and thermal properties

Wangqing Wu et al.

Summary: A measurement method for the plasticization rate of ultrasonic plasticization microinjection molding was proposed. The effect of ultrasonic amplitude on the plasticization rate and properties of polypropylene (PP) rods was investigated. Results showed that the plasticization rate increased by 186% with the increase of ultrasonic amplitude. The mechanical and thermal properties of the PP samples remained stable, with improved thermal properties after ultrasonic plasticization.

POLYMER TESTING (2023)

添加到收藏夹

Review Engineering, Biomedical

Microneedles: materials, fabrication, and biomedical applications

Xiaojin Luo et al.

Summary: The microneedles have attracted great interests for a wide range of transdermal biomedical applications, such as biosensing and drug delivery, due to the advantages of being painless, semi-invasive, and sustainable. The ongoing challenges are the materials and fabrication methods of the microneedles in order to obtain a specific shape, configuration and function of the microneedles to achieve a target biomedical application.

BIOMEDICAL MICRODEVICES (2023)

添加到收藏夹

Article Nanoscience & Nanotechnology

3D-assembled microneedle ion sensor-based wearable system for the transdermal monitoring of physiological ion fluctuations

Xinshuo Huang et al.

Summary: Monitoring human health is crucial in biomedicine, and blood ion concentrations serve as important reference indicators for many diseases. Microneedle array-based sensors have enabled continuous health monitoring by being minimally invasive. In this study, we developed a microneedle sensing-array integrated system that can continuously detect subcutaneous ions for real-time human health monitoring. The system overcomes limitations in preparing 3D microneedle structures with multiple electrode channels and tackles challenges in modifying closely spaced microneedle tips into different types of electrodes. The system exhibits sufficient sensitivity and good detection performance, as demonstrated by in vivo experiments on rats. By integrating the sensor into a wearable monitoring system, it can potentially provide feedback on diseases related to physiological ion changes.

MICROSYSTEMS & NANOENGINEERING (2023)

添加到收藏夹

Review Engineering, Biomedical

Going below and beyond the surface: Microneedle structure, materials, drugs, fabrication, and applications for wound healing and tissue regeneration

Shang Lyu et al.

Summary: Microneedles have gained widespread attention as a novel drug delivery system due to their non-invasiveness, painless administration, controllable drug delivery, and versatile cargo loading capacity. In addition to transdermal drug delivery, microneedles have shown promising results in promoting wound healing and tissue regeneration. This review provides an overview of microneedle systems, including potential cargos, structural designs, material selection, and drug release mechanisms. It also summarizes different fabrication methods and the recent progress of microneedle-assisted wound healing and tissue regeneration in various tissues and organs.

BIOACTIVE MATERIALS (2023)

添加到收藏夹

Article Chemistry, Analytical

Determination of Transdermal Rate of Metallic Microneedle Array through an Impedance Measurements-Based Numerical Check Screening Algorithm

Jingshan Mo et al.

Summary: This study demonstrates a method based on impedance measurements and numerical check screening algorithm to determine the transdermal rate of metallic microneedle arrays. Different sizes of metallic sheet microneedle array sensors were fabricated to evaluate different transdermal rates, and in vitro sensing experiments confirmed the effect of transdermal rate on sensing outcomes. Two methods for calculating the transdermal rate were derived, providing foundations for real-time transdermal rate estimation.

MICROMACHINES (2022)

添加到收藏夹

Article Multidisciplinary Sciences

Bioinspired Rotation Microneedles for Accurate Transdermal Positioning and Ultraminimal-Invasive Biomarker Detection with Mechanical Robustness

Yilin Cai et al.

Summary: In this study, we introduce bioinspired rotation microneedles for accurate positioning, reduced penetration force, and decreased skin deformation. These microneedles are applied in biological sample extraction and monitoring of proinflammatory cytokines, achieving ultrasensitive detection using only one microneedle.

RESEARCH (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

In Vivo Transdermal Multi-Ion Monitoring with a Potentiometric Microneedle-Based Sensor Patch

Agueda Molinero-Fernandez et al.

Summary: Microneedle sensor technology offers exciting opportunities for decentralized clinical analyses. This paper introduces a novel method using membrane-based microneedles for real-time, on-body monitoring of multiple ions simultaneously. This technology is clinically relevant for assessing electrolyte disorders and other clinical conditions.

ACS SENSORS (2022)

添加到收藏夹

Article Chemistry, Physical

Rapidly separable bubble microneedle patch for effective local anesthesia

Yuan Yang et al.

Summary: A lidocaine/hyaluronic acid bubble microneedle patch was developed for rapid drug delivery and efficient analgesia, providing a promising alternative for local anesthesia.

NANO RESEARCH (2022)

添加到收藏夹

Article Engineering, Biomedical

Microneedle patch for the ultrasensitive quantification of protein biomarkers in interstitial fluid

Zheyu Wang et al.

Summary: Microneedle patches enable rapid sampling and on-needle quantification of target protein biomarkers in interstitial fluid, offering a new possibility for early disease diagnosis.

NATURE BIOMEDICAL ENGINEERING (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

Design and optimization of a microneedle with skin insertion analysis for transdermal drug delivery applications

Md Asadujjaman Sawon et al.

Summary: This paper introduces a silicon carbide microneedle with six lumens, a total length of about 350 μm, and inner and outer diameters of 30 μm and 52 μm respectively. The microneedle's performance is analyzed using COMSOL multiphysics software, an optimized microneedle tip is designed, and flow analyses of various viscosity based fluids inside the microneedle are conducted. Simulation results confirm that the proposed microneedle successfully penetrates a skin model and remains intact.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Rolling microneedle electrode array (RoMEA) empowered nucleic acid delivery and cancer immunotherapy

Tongren Yang et al.

Summary: Topical administration of siRNA is a promising therapeutic modality, and RoMEA, an engineered rolling microneedle electrode array, enables efficient and extensive siRNA therapy. The use of RoMEA leads to effective siRNA delivery and gene silencing.

NANO TODAY (2021)

添加到收藏夹

Article Engineering, Manufacturing

Controlling the geometry of laser ablated microneedle cavities in different mould materials and assessing the replication fidelity within polymer injection moulding

Tim Evens et al.

Summary: The study investigated the effects of laser scanning parameters on the geometry of microneedle cavities during the production process, as well as the influence of injection molding materials and mold materials on the quality of the products.

JOURNAL OF MANUFACTURING PROCESSES (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

A highly robust approach to fabricate the mass-customizable mold of sharp-tipped biodegradable polymer microneedles for drug delivery

Hyeoncheol Lim et al.

Summary: In this study, a robust method for fabricating mass-customizable master molds for sharp-tipped biodegradable polymer microneedles is developed. The method combines predrying and chip casting (PCC) with substrateless, inclined, and rotational exposure (SIR exposure), and has been proven to be highly compatible with almost all existing biodegradable polymers. The findings of this study contribute to a significant growth of dissolving microneedle-mediated drug delivery and enhance the understanding of drug release kinetics.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

Development and preclinical evaluation of microneedle-assisted resveratrol loaded nanostructured lipid carriers for localized delivery to breast cancer therapy

Shivaprasad Gadag et al.

Summary: Resveratrol-loaded nanostructured lipid carriers (NLCs) delivered through microneedle arrays showed improved skin permeation and anticancer activity on breast cancer cell lines, indicating their potential as an effective strategy for localized drug delivery in breast cancer therapy.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

添加到收藏夹

Article Engineering, Manufacturing

Simulation assisted design for microneedle manufacturing: Computational modeling of two-photon templated electrodeposition

Aykut Aksit et al.

Summary: The hybrid additive methodology of twophoton templated electrodeposition (2PTE) allows for the fabrication of fully metallic micrometer-scale 3D architectures with complex geometries, such as microneedles, for precision surgical applications. However, challenges arise from electrochemical deposition of metals into thick 3D lithography patterns, leading to potential and chemical gradients that affect design limitations. Numerical modeling serves as a design tool to predict growth and explore geometric constraints of manufacturing complicated 3D metallic structures through the 2PTE method.

JOURNAL OF MANUFACTURING PROCESSES (2021)

添加到收藏夹

Article Engineering, Chemical

Ultrasonic Extrusion of NR Gum and Its Effect on the Structure and Properties of Unfilled and Silica-Filled NR

Tian Liang et al.

POLYMER ENGINEERING AND SCIENCE (2020)

添加到收藏夹

Review Acoustics

Ultrasonic moulding: Current state of the technology

Marcel Janer et al.

ULTRASONICS (2020)

添加到收藏夹

Article Physics, Applied

Solid and hollow metallic glass microneedles for transdermal drug-delivery

Zhonglue Hu et al.

APPLIED PHYSICS LETTERS (2020)

添加到收藏夹

Article Pharmacology & Pharmacy

Optimal scaling analysis of polymeric microneedle length and its effect on transdermal insulin delivery

Shoukai Chen et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2020)

添加到收藏夹

Article Multidisciplinary Sciences

A basal-bolus insulin regimen integrated microneedle patch for intraday postprandial glucose control

Bo Zhi Chen et al.

SCIENCE ADVANCES (2020)

添加到收藏夹

Review Pharmacology & Pharmacy

Current trends in polymer microneedle for transdermal drug delivery

Khater Ahmed Saeed AL-Japairai et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

添加到收藏夹

Article Chemistry, Analytical

Characterization of Stereolithography Printed Soft Tooling for Micro Injection Molding

Daniel Dempsey et al.

MICROMACHINES (2020)

添加到收藏夹

Article Engineering, Manufacturing

Ultrasonic micromoulding: Process characterisation using extensive in -line monitoring for micro-scaled products

Mert Gulcur et al.

JOURNAL OF MANUFACTURING PROCESSES (2020)

添加到收藏夹

Article Engineering, Manufacturing

Twice Stretched Fabrication of Polylactic Acid Microneedle Arrays Using Drawing Lithography

Shingo Terashima et al.

INTERNATIONAL JOURNAL OF PRECISION ENGINEERING AND MANUFACTURING (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Silk/polyols/GOD microneedle based electrochemical biosensor for continuous glucose monitoring

Liang Zhao et al.

RSC ADVANCES (2020)

添加到收藏夹

Article Pharmacology & Pharmacy

Self-implanted tiny needles as alternative to traditional parenteral administrations for controlled transdermal drug delivery

Bo Zhi Chen et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)

添加到收藏夹

Article Polymer Science

Characterization of the Fluidity of the Ultrasonic Plasticized Polymer Melt by Spiral Flow Testing under Micro-Scale

Bingyan Jiang et al.

POLYMERS (2019)

添加到收藏夹

Review Polymer Science

Ultrasonic Molding Technology: Recent Advances and Potential Applications in the Medical Industry

Ulisses Heredia-Rivera et al.

POLYMERS (2019)

添加到收藏夹

Article Multidisciplinary Sciences

Bio-inspired clamping microneedle arrays from flexible ferrofluid-configured moldings

Xiaoxuan Zhang et al.

SCIENCE BULLETIN (2019)

添加到收藏夹

Article Polymer Science

Study on the Mechanism of Interfacial Friction Heating in Polymer Ultrasonic Plasticization Injection Molding Process

Tao Peng et al.

POLYMERS (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Wearable Electrochemical Microneedle Sensor for Continuous Monitoring of Levodopa: Toward Parkinson Management

K. Yugender Goud et al.

ACS SENSORS (2019)

添加到收藏夹

Article Nanoscience & Nanotechnology

Simple and customizable method for fabrication of high-aspect ratio microneedle molds using low-cost 3D printing

Kevin J. Krieger et al.

MICROSYSTEMS & NANOENGINEERING (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Effects of Ultrasonication on the Conformational, Microstructural, and Antioxidant Properties of Konjac Glucomannan

Jun-Yi Yin et al.

APPLIED SCIENCES-BASEL (2019)

添加到收藏夹

Article Materials Science, Biomaterials

Transdermal delivery of therapeutics through dissolvable gelatin/sucrose films coated on PEGDA microneedle arrays with improved skin permeability

Ya Gao et al.

JOURNAL OF MATERIALS CHEMISTRY B (2019)

添加到收藏夹

Article Nanoscience & Nanotechnology

Safety Evaluation of Solid Polymer Microneedles in Human Volunteers at Different Application Sites

Bo Zhi Chen et al.

ACS APPLIED BIO MATERIALS (2019)

添加到收藏夹

Article Engineering, Electrical & Electronic

Ultrasonic vibration technology for the polymer replication of high aspect ratio micro-structured surface

Junhui Liu et al.

MICROSYSTEM TECHNOLOGIES-MICRO-AND NANOSYSTEMS-INFORMATION STORAGE AND PROCESSING SYSTEMS (2018)

添加到收藏夹

Article Multidisciplinary Sciences

Mechanisms of sampling interstitial fluid from skin using a microneedle patch

Pradnya P. Samant et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

添加到收藏夹

Article Chemistry, Physical

Replicability of Ultrasonic Molding for Processing Thin-Wall Polystyrene Plates with a Microchannel

I. Ferrer et al.

MATERIALS (2018)

添加到收藏夹

Article Materials Science, Biomaterials

Bioceramic microneedle arrays are able to deliver OVA to dendritic cells in human skin

Helen Vallhov et al.

JOURNAL OF MATERIALS CHEMISTRY B (2018)

添加到收藏夹

Article Engineering, Manufacturing

Replication integrity of micro features using variotherm and vacuum assisted microinjection moulding

Nan Zhang et al.

CIRP JOURNAL OF MANUFACTURING SCIENCE AND TECHNOLOGY (2018)

添加到收藏夹

Article Materials Science, Multidisciplinary

Micro injection molding processing of UHMWPE using ultrasonic vibration energy

Xavier Sanchez-Sanchez et al.

MATERIALS & DESIGN (2017)

添加到收藏夹

Article Biophysics

Continuous minimally-invasive alcohol monitoring using microneedle sensor arrays

A. M. Vinu Mohan et al.

BIOSENSORS & BIOELECTRONICS (2017)

添加到收藏夹

Article Engineering, Electrical & Electronic

Characterization of skin penetration efficacy by Au-coated Si microneedle array electrode

D. Resnik et al.

SENSORS AND ACTUATORS A-PHYSICAL (2015)

添加到收藏夹

Article Chemistry, Analytical

Collection of Analytes from Microneedle Patches

Andrey V. Romanyuk et al.

ANALYTICAL CHEMISTRY (2014)

添加到收藏夹

Article Acoustics

Effects of ultrasonic vibration on the micro-molding processing of polylactide

Matias Sacristan et al.

ULTRASONICS SONOCHEMISTRY (2014)

添加到收藏夹

Article Materials Science, Biomaterials

Self-setting bioceramic microscopic protrusions for transdermal drug delivery

Bing Cai et al.

JOURNAL OF MATERIALS CHEMISTRY B (2014)

添加到收藏夹

Article Engineering, Electrical & Electronic

Manufacturing of polymer micro parts by ultrasonic plasticization and direct injection

Walter Michaeli et al.

MICROSYSTEM TECHNOLOGIES-MICRO-AND NANOSYSTEMS-INFORMATION STORAGE AND PROCESSING SYSTEMS (2011)

添加到收藏夹

Review Nanoscience & Nanotechnology

Drug delivery through the skin: molecular simulations of barrier lipids to design more effective noninvasive dermal and transdermal delivery systems for small molecules, biologics, and cosmetics

J. Torin Huzil et al.

WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2011)

添加到收藏夹

Review Chemistry, Multidisciplinary

Advances in transcutaneous vaccine delivery: Do all ways lead to Rome?

Suzanne M. Bal et al.

JOURNAL OF CONTROLLED RELEASE (2010)

添加到收藏夹

Article Acoustics

Physical and chemical effects of ultrasound vibration on polymer melt in extrusion

Jinyao Chen et al.

ULTRASONICS SONOCHEMISTRY (2010)

添加到收藏夹

Review Biochemistry & Molecular Biology

The skin barrier in healthy and diseased state

Joke A. Bouwstra et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2006)

添加到收藏夹

Review Pharmacology & Pharmacy

Microneedles for transdermal drug delivery

MR Prausnitz

ADVANCED DRUG DELIVERY REVIEWS (2004)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.