The Paradoxical Association of Lipids with Survival and Walking Ability of Hip Fractures in Geriatric Patients After Surgery: A 1-Year Follow-Up Study

Background: We aimed to explore the association between lipids and the survival and walking ability of hip fractures in geriatric patients after surgery.Methods: Restricted cubic spline (RCS) was established to explore the nonlinear relationship between lipids and 1-year mortality of hip fractures, and the cut-off points were also determined by RCS. Then, the patients were divided into three groups: low, middle, and high levels of LDL-c. Then, the survival and walking ability of patients from different groups were compared, and the Cox regression and Logistics regression were used to identify the relationships between lipids and the survival and walking ability of hip fractures.Results: The patients with middle levels of LDL-c had a significantly high survival probability than those with low or high levels of LDL-c (p < 0.001). The patients with low levels of LDL-c and with high levels of LDL-c may have a poor prognosis compared with patients with middle levels of LDL-c in 6-month mortality, 6-month free walking ability, 1-year mortality, and 1-year free walking ability (All p < 0.05).Conclusion: Low and high levels of LDL-c may both relate to the poor survival and walking ability of hip fractures.

Automated summary

This study aimed to explore the association between lipids and the survival and walking ability of hip fractures in geriatric patients after surgery. Restricted cubic spline was used to establish the nonlinear relationship, and the patients were divided into low, middle, and high levels of LDL-c. The results showed that patients with middle levels of LDL-c had a significantly higher survival probability, and low and high levels of LDL-c were associated with poor prognosis in terms of mortality and free walking ability.