期刊
NATURE REVIEWS MOLECULAR CELL BIOLOGY
卷 17, 期 12, 页码 741-742出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrm.2016.151
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资金
- NHGRI NIH HHS [R01 HG003143] Funding Source: Medline
The spatial organization of genomes is studied using microscopy-and chromosome conformation capture (3C)-based methods. The two types of methods produce data that are often consistent, but there are cases where they appear discordant. These cases provide opportunities to derive better models of chromatin folding, which can reconcile the datasets.
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