4.6 Article

Behavioral and Neuropathological Phenotyping of the Tau58/2 and Tau58/4 Transgenic Mouse Models for FTDP-17

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Behavioral Sciences

Behavioural disinhibition in frontotemporal dementia investigated within an ecological framework

Delphine Tanguy et al.

Summary: Disinhibition is a core symptom in bvFTD, but its characterization and management options are still unclear. This study explored disinhibition in an original semi-ecological situation and identified different subtypes of disinhibition, highlighting the importance of differentiation and non-pharmacological management.

CORTEX (2023)

Article Behavioral Sciences

Cannabidiol (CBD) treatment improves spatial memory in 14-month-old female TAU58/2 transgenic mice

Fabian Kreilaus et al.

Summary: This study investigated the therapeutic effects of CBD on transgenic mice and found that CBD can improve behavioural deficits and cognitive impairments associated with FTD and AD.

BEHAVIOURAL BRAIN RESEARCH (2022)

Article Behavioral Sciences

The behavioural phenotype of 14-month-old female TAU58/2 transgenic mice

Fabian Kreilaus et al.

Summary: TAU58/2 transgenic female mice at 14 months of age showed significant motor deficits and lower bodyweight compared to WT littermates. They failed to habituate to the test arena in the light-dark test, and exhibited impaired long-term spatial memory while showing intact intermediate-term spatial learning in the cheeseboard test.

BEHAVIOURAL BRAIN RESEARCH (2021)

Review Clinical Neurology

What Do We Mean by Behavioral Disinhibition in Frontotemporal Dementia?

Nahuel Magrath Guimet et al.

Summary: Behavioral variant frontotemporal dementia is characterized by changes in behavior, personality, and language, with disinhibition being a core symptom. However, there is no single definition that fully captures the behavioral symptoms observed in patients.

FRONTIERS IN NEUROLOGY (2021)

Article Clinical Neurology

Longitudinal changes in EEG power, sleep cycles and behaviour in a tau model of neurodegeneration

C. M. Holton et al.

ALZHEIMERS RESEARCH & THERAPY (2020)

Article Behavioral Sciences

Chronic cannabidiol (CBD) treatment did not exhibit beneficial effects in 4-month-old male TAU58/2 transgenic mice

Georgia Watt et al.

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2020)

Article Biochemistry & Molecular Biology

CNS cell type-specific gene profiling of P301S tau transgenic mice identifies genes dysregulated by progressive tau accumulation

Yazi D. Ke et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2019)

Article Behavioral Sciences

Sleep architecture changes in the APP23 mouse model manifest at onset of cognitive deficits

Jan Van Erum et al.

BEHAVIOURAL BRAIN RESEARCH (2019)

Article Multidisciplinary Sciences

QuPath: Open source software for digital pathology image analysis

Peter Bankhead et al.

SCIENTIFIC REPORTS (2017)

Article Geriatrics & Gerontology

Metabolic changes over the course of aging in a mouse model of tau deposition

Aurelie Joly-Amado et al.

NEUROBIOLOGY OF AGING (2016)

Article Behavioral Sciences

Impulsivity, decreased social exploration, and executive dysfunction in a mouse model of frontotemporal dementia

Ann Van der Jeugd et al.

NEUROBIOLOGY OF LEARNING AND MEMORY (2016)

Article Clinical Neurology

You stole my food! Eating alterations in frontotemporal dementia

Marilena Aiello et al.

NEUROCASE (2016)

Article Clinical Neurology

Early-onset axonal pathology in a novel P301S-Tau transgenic mouse model of frontotemporal lobar degeneration

J. van Eersel et al.

NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2015)

Article Behavioral Sciences

Partial rescue of memory deficits induced by calorie restriction in a mouse model of tau deposition

Milene L. Brownlow et al.

BEHAVIOURAL BRAIN RESEARCH (2014)

Review Clinical Neurology

Frontotemporal dementia: diagnosis, deficits and management

Nicholas T. Bott et al.

NEURODEGENERATIVE DISEASE MANAGEMENT (2014)

Review Clinical Neurology

Tau pathology and neurodegeneration

Maria Grazia Spillantini et al.

LANCET NEUROLOGY (2013)

Article Clinical Neurology

Eating and Hypothalamus Changes in Behavioral-Variant Frontotemporal Dementia

Olivier Piguet et al.

ANNALS OF NEUROLOGY (2011)

Review Neurosciences

Brain regions and genes affecting limb-clasping responses

R. Lalonde et al.

BRAIN RESEARCH REVIEWS (2011)

Article Clinical Neurology

Disrupted sleep and circadian patterns in frontotemporal dementia

K. N. Anderson et al.

EUROPEAN JOURNAL OF NEUROLOGY (2009)

Review Clinical Neurology

Neuropathology and Cognitive Impairment in Alzheimer Disease: A Complex but Coherent Relationship

Peter T. Nelson et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2009)

Review Neurosciences

Tests to assess motor phenotype in mice: a user's guide

Simon P. Brooks et al.

NATURE REVIEWS NEUROSCIENCE (2009)

Review Geriatrics & Gerontology

Knock-out and transgenic mouse models of tauopathies

Franziska Denk et al.

NEUROBIOLOGY OF AGING (2009)

Review Neurosciences

Animal models of Alzheimer's disease and frontotemporal dementia

Jurgen Gotz et al.

NATURE REVIEWS NEUROSCIENCE (2008)

Review Clinical Neurology

Tauopathy models and human neuropathology: similarities and differences

Stephan Frank et al.

ACTA NEUROPATHOLOGICA (2008)

Article Behavioral Sciences

Mood and male sexual behaviour in the APP23 model of Alzheimer's disease

Ellen Vloeberghs et al.

BEHAVIOURAL BRAIN RESEARCH (2007)

Article Pathology

Early axonopathy preceding neurofibrillary tangles in mutant tau transgenic mice

Karelle Leroy et al.

AMERICAN JOURNAL OF PATHOLOGY (2007)

Article Medicine, General & Internal

Barbering in mice: a model for trichotillomania

BT Kurien et al.

BMJ-BRITISH MEDICAL JOURNAL (2005)

Review Biochemistry & Molecular Biology

Transgenic animal models of tauopathies

VMY Lee et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2005)

Article Neurosciences

Altered circadian locomotor activity in APP23 mice: a model for BPSD disturbances

E Vloeberghs et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2004)

Article Neurosciences

Age-dependent cognitive decline in the APP23 model precedes amyloid deposition

D Van Dam et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2003)

Review Biochemistry & Molecular Biology

Analysis of tauopathies with transgenic mice

M Hutton et al.

TRENDS IN MOLECULAR MEDICINE (2001)

Review Neurosciences

Applications of the Morris water maze in the study of learning and memory

R D'Hooge et al.

BRAIN RESEARCH REVIEWS (2001)

Article Clinical Neurology

Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein

A Probst et al.

ACTA NEUROPATHOLOGICA (2000)