相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Multiple Origins of Virus Persistence during Natural Control of HIV Infection
Eli A. Boritz et al.
CELL (2016)
Antiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults 2016 Recommendations of the International Antiviral Society-USA Panel
Huldrych F. Gunthard et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2016)
The Cleavage and Polyadenylation Specificity Factor 6 (CPSF6) Subunit of the Capsid-recruited Pre-messenger RNA Cleavage Factor I (CFIm) Complex Mediates HIV-1 Integration into Genes
Sheeba Rasheedi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Comparative Analysis of HIV-1 and Murine Leukemia Virus Three-Dimensional Nuclear Distributions
Valentina Quercioli et al.
JOURNAL OF VIROLOGY (2016)
Chromatin Domains: The Unit of Chromosome Organization
Jesse R. Dixon et al.
MOLECULAR CELL (2016)
CRISPR-Cas9 Can Inhibit HIV-1 Replication but NHEJ Repair Facilitates Virus Escape
Gang Wang et al.
MOLECULAR THERAPY (2016)
Defective proviruses rapidly accumulate during acute HIV-1 infection
Katherine M. Bruner et al.
NATURE MEDICINE (2016)
Organization and function of the 3D genome
Boyan Bonev et al.
NATURE REVIEWS GENETICS (2016)
A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin
Gregory A. Sowd et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Reservoir expansion by T-cell proliferation may be another barrier to curing HIV infection
Michelle Kim et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Clonally expanded CD4+ T cells can produce infectious HIV-1 in vivo
Francesco R. Simonetti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Understanding HIV Latency: The Road to an HIV Cure
Matthew S. Dahabieh et al.
ANNUAL REVIEW OF MEDICINE, VOL 66 (2015)
Retroviral integration: Site matters: Mechanisms and consequences of retroviral integration site selection
Jonas Demeulemeester et al.
BIOESSAYS (2015)
HIV-1 Integration Landscape during Latent and Active Infection
Lillian B. Cohn et al.
CELL (2015)
HIV-1 integrase inhibition: looking at cofactor interactions
Frauke Christ et al.
FUTURE MEDICINAL CHEMISTRY (2015)
LEDGF/p75 interacts with mRNA splicing factors and targets HIV-1 integration to highly spliced genes
Parmit Kumar Singh et al.
GENES & DEVELOPMENT (2015)
Nuclear pore proteins and the control of genome functions
Arkaitz Ibarra et al.
GENES & DEVELOPMENT (2015)
Directed targeting of chromatin to the nuclear lamina is mediated by chromatin state and A-type lamins
Jennifer C. Harr et al.
JOURNAL OF CELL BIOLOGY (2015)
Regulation of HIV-1 Latency by Chromatin Structure and Nuclear Architecture
Marina Lusic et al.
JOURNAL OF MOLECULAR BIOLOGY (2015)
Impact of Nucleoporin-Mediated Chromatin Localization and Nuclear Architecture on HIV Integration Site Selection
Richard W. Wong et al.
JOURNAL OF VIROLOGY (2015)
Structural basis for retroviral integration into nucleosomes
Daniel P. Maskell et al.
NATURE (2015)
Nuclear architecture dictates HIV-1 integration site selection
Bruna Marini et al.
NATURE (2015)
Damaging the Integrated HIV Proviral DNA with TALENs
Christy L. Strong et al.
PLOS ONE (2015)
Host factors for retroviral integration site selection
Zeger Debyser et al.
TRENDS IN BIOCHEMICAL SCIENCES (2015)
Long-Range Chromatin Interactions
Job Dekker et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2015)
Use of the CRISPR/Cas9 system as an intracellular defense against HIV-1 infection in human cells
Hsin-Kai Liao et al.
NATURE COMMUNICATIONS (2015)
Chromatin organization at the nuclear pore favours HIV replication
Mickael Lelek et al.
NATURE COMMUNICATIONS (2015)
Direct Visualization of HIV-1 Replication Intermediates Shows that Capsid and CPSF6 Modulate HIV-1 Intra-nuclear Invasion and Integration
Christopher R. Chin et al.
CELL REPORTS (2015)
HIV-1 Integrase Variants Retarget Viral Integration and Are Associated with Disease Progression in a Chronic Infection Cohort
Jonas Demeulemeester et al.
CELL HOST & MICROBE (2014)
Integrase residues that determine nucleotide preferences at sites of HIV-1 integration: implications for the mechanism of target DNA binding
Erik Serrao et al.
NUCLEIC ACIDS RESEARCH (2014)
RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection
Wenhui Hu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Structural basis of HIV-1 capsid recognition by PF74 and CPSF6
Akash Bhattacharya et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection
Thor A. Wagner et al.
SCIENCE (2014)
Specific HIV integration sites are linked to clonal expansion and persistence of infected cells
F. Maldarelli et al.
SCIENCE (2014)
A model for cofactor use during HIV-1 reverse transcription and nuclear entry
Laura Hilditch et al.
CURRENT OPINION IN VIROLOGY (2014)
Quantitative microscopy of functional HIV post-entry complexes reveals association of replication with the viral capsid
Ke Peng et al.
ELIFE (2014)
HIV-1 Vpr-a still enigmatic multitasker
Carolin A. Guenzel et al.
FRONTIERS IN MICROBIOLOGY (2014)
Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure
Ya-Chi Ho et al.
CELL (2013)
Single-Cell Dynamics of Genome-Nuclear Lamina Interactions
Jop Kind et al.
CELL (2013)
Proximity to PML Nuclear Bodies Regulates HIV-1 Latency in CD4+T Cells
Marina Lusic et al.
CELL HOST & MICROBE (2013)
Presence of C11orf95-MKL2 fusion is a consistent finding in chondroid lipomas: a study of eight cases
Uta Flucke et al.
HISTOPATHOLOGY (2013)
Differential Effects of Human Immunodeficiency Virus Type 1 Capsid and Cellular Factors Nucleoporin 153 and LEDGF/p75 on the Efficiency and Specificity of Viral DNA Integration
Yasuhiro Koh et al.
JOURNAL OF VIROLOGY (2013)
A Doubly Fluorescent HIV-1 Reporter Shows that the Majority of Integrated HIV-1 Is Latent Shortly after Infection
Matthew S. Dahabieh et al.
JOURNAL OF VIROLOGY (2013)
Functional implications of genome topology
Giacomo Cavalli et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)
Structural basis for high-affinity binding of LEDGF PWWP to mononucleosomes
Jocelyn O. Eidahl et al.
NUCLEIC ACIDS RESEARCH (2013)
Zinc-finger-nucleases mediate specific and efficient excision of HIV-1 proviral DNA from infected and latently infected human T cells
Xiying Qu et al.
NUCLEIC ACIDS RESEARCH (2013)
Nuclear import of APOBEC3F-labeled HIV-1 preintegration complexes
Ryan C. Burdick et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions
Belete Ayele Desimmie et al.
RETROVIROLOGY (2013)
HIV latency and integration site placement in five cell-based models
Scott Sherrill-Mix et al.
RETROVIROLOGY (2013)
HIV-1 transcription and latency: an update
Carine Van Lint et al.
RETROVIROLOGY (2013)
TNPO3 protects HIV-1 replication from CPSF6-mediated capsid stabilization in the host cell cytoplasm
Alberto De Iaco et al.
RETROVIROLOGY (2013)
Dual-color HIV reporters trace a population of latently infected cells and enable their purification
Vincenzo Calvanese et al.
VIROLOGY (2013)
Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication
Francesca Di Nunzio et al.
VIROLOGY (2013)
Viral and Cellular Requirements for the Nuclear Entry of Retroviral Preintegration Nucleoprotein Complexes
Kenneth A. Matreyek et al.
VIRUSES-BASEL (2013)
Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus
Hirotaka Ebina et al.
SCIENTIFIC REPORTS (2013)
Nucleoporin NUP153 Phenylalanine-Glycine Motifs Engage a Common Binding Pocket within the HIV-1 Capsid Protein to Mediate Lentiviral Infectivity
Kenneth A. Matreyek et al.
PLOS PATHOGENS (2013)
Comparative Analysis of Measures of Viral Reservoirs in HIV-1 Eradication Studies
Susanne Eriksson et al.
PLOS PATHOGENS (2013)
Highly Significant Antiviral Activity of HIV-1 LTR-Specific Tre-Recombinase in Humanized Mice
Ilona Hauber et al.
PLOS PATHOGENS (2013)
Nuclear bodies: multifunctional companions of the genome
Miroslav Dundr
CURRENT OPINION IN CELL BIOLOGY (2012)
HIV-1 Capsid-Targeting Domain of Cleavage and Polyadenylation Specificity Factor 6
KyeongEun Lee et al.
JOURNAL OF VIROLOGY (2012)
A quantitative basis for antiretroviral therapy for HIV-1 infection
Benjamin L. Jilek et al.
NATURE MEDICINE (2012)
Nuclear pore complex composition: a new regulator of tissue-specific and developmental functions
Marcela Raices et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
HIV DNA Integration
Robert Craigie et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)
Psip1/Ledgf p52 Binds Methylated Histone H3K36 and Splicing Factors and Contributes to the Regulation of Alternative Splicing
Madapura M. Pradeepa et al.
PLOS GENETICS (2012)
LEDGF/p75-Independent HIV-1 Replication Demonstrates a Role for HRP-2 and Remains Sensitive to Inhibition by LEDGINs
Rik Schrijvers et al.
PLOS PATHOGENS (2012)
Resistance associated mutations to dolutegravir (S/GSK1349572) in HIV-infected patients - Impact of HIV subtypes and prior raltegravir experience
Carolina Garrido et al.
ANTIVIRAL RESEARCH (2011)
The TRIM Family Protein KAP1 Inhibits HIV-1 Integration
Awatef Allouch et al.
CELL HOST & MICROBE (2011)
被撤回的出版物: Role of the PWWP Domain of Lens Epithelium-derived Growth Factor (LEDGF)/p75 Cofactor in Lentiviral Integration Targeting (Retracted article. See vol. 293, pg. 114, 2018)
Rik Gijsbers et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Influence of Host Gene Transcription Level and Orientation on HIV-1 Latency in a Primary-Cell Model
Liang Shan et al.
JOURNAL OF VIROLOGY (2011)
Epigenetic Silencing of HIV-1 by the Histone H3 Lysine 27 Methyltransferase Enhancer of Zeste 2
Julia Friedman et al.
JOURNAL OF VIROLOGY (2011)
HIV Latency
Robert F. Siliciano et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2011)
HIV-1 Capsid-Cyclophilin Interactions Determine Nuclear Import Pathway, Integration Targeting and Replication Efficiency
Torsten Schaller et al.
PLOS PATHOGENS (2011)
HIV Integration Targeting: A Pathway Involving Transportin-3 and the Nuclear Pore Protein RanBP2
Karen E. Ocwieja et al.
PLOS PATHOGENS (2011)
Functional Coupling between HIV-1 Integrase and the SWI/SNF Chromatin Remodeling Complex for Efficient in vitro Integration into Stable Nucleosomes
Paul Lesbats et al.
PLOS PATHOGENS (2011)
Flexible Use of Nuclear Import Pathways by HIV-1
KyeongEun Lee et al.
CELL HOST & MICROBE (2010)
Protein Tpr is required for establishing nuclear pore-associated zones of heterochromatin exclusion
Sandra Krull et al.
EMBO JOURNAL (2010)
Involvement of Histone H3 Lysine 9 (H3K9) Methyltransferase G9a in the Maintenance of HIV-1 Latency and Its Reactivation by BIX01294
Kenichi Imai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Activity of Elvitegravir, a Once-Daily Integrase Inhibitor, against Resistant HIV Type 1: Results of a Phase 2, Randomized, Controlled, Dose-Ranging Clinical Trial
Andrew R. Zolopa et al.
JOURNAL OF INFECTIOUS DISEASES (2010)
Retroviral intasome assembly and inhibition of DNA strand transfer
Stephen Hare et al.
NATURE (2010)
The mechanism of retroviral integration from X-ray structures of its key intermediates
Goedele N. Maertens et al.
NATURE (2010)
Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication
Frauke Christ et al.
NATURE CHEMICAL BIOLOGY (2010)
Concerted action of cellular JNK and Pin1 restricts HIV-1 genome integration to activated CD4+ T lymphocytes
Lara Manganaro et al.
NATURE MEDICINE (2010)
A cooperative and specific DNA-binding mode of HIV-1 integrase depends on the nature of the metallic cofactor and involves the zinc-containing N-terminal domain
Kevin Carayon et al.
NUCLEIC ACIDS RESEARCH (2010)
High-resolution profiling of the LEDGF/p75 chromatin interaction in the ENCODE region
Jan De Rijck et al.
NUCLEIC ACIDS RESEARCH (2010)
Lens epithelium-derived growth factor fusion proteins redirect HIV-1 DNA integration
Andrea L. Ferris et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Structure-based modeling of the functional HIV-1 intasome and its inhibition
Lavanya Krishnan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
HIV integration site distributions in resting and activated CD4+ T cells infected in culture
Troy Brady et al.
AIDS (2009)
Transcriptional competence of the integrated HIV-1 provirus at the nuclear periphery
Mariacarolina Dieudonne et al.
EMBO JOURNAL (2009)
An Allosteric Mechanism for Inhibiting HIV-1 Integrase with a Small Molecule
Jacques J. Kessl et al.
MOLECULAR PHARMACOLOGY (2009)
Host Cell Factors in HIV Replication: Meta-Analysis of Genome-Wide Studies
Frederic D. Bushman et al.
PLOS PATHOGENS (2009)
CpG Methylation Controls Reactivation of HIV from Latency
Jana Blazkova et al.
PLOS PATHOGENS (2009)
Epigenetic Regulation of HIV-1 Latency by Cytosine Methylation
Steven E. Kauder et al.
PLOS PATHOGENS (2009)
Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication
Renate Konig et al.
CELL (2008)
Orientation-dependent regulation of integrated HIV-1 expression by host gene transcriptional readthrough
Yefei Han et al.
CELL HOST & MICROBE (2008)
Transcriptional interference antagonizes proviral gene expression to promote HIV latency
Tina Lenasi et al.
CELL HOST & MICROBE (2008)
Transportin-SR2 imports HIV into the nucleus
Frauke Christ et al.
CURRENT BIOLOGY (2008)
Acetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcription
Arianna Sabo et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions
Lars Guelen et al.
NATURE (2008)
Dose-response curve slope sets class-specific limits on inhibitory potential of anti-HIV drugs
Lin Shen et al.
NATURE MEDICINE (2008)
HIV-1 Pre-Integration Complexes Selectively Target Decondensed Chromatin in the Nuclear Periphery
Alberto Albanese et al.
PLOS ONE (2008)
Decay dynamics of HIV-1 depend on the inhibited stages of the viral life cycle
Ahmad R. Sedaghat et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Identification of host proteins required for HIV infection through a functional genomic screen
Abraham L. Brass et al.
SCIENCE (2008)
Subdiffraction multicolor imaging of the nuclear periphery with 3D structured illumination microscopy
Lothar Schermelleh et al.
SCIENCE (2008)
Evidence for direct involvement of the capsid protein in HIV infection of nondividing cells
Masahiro Yamashita et al.
PLOS PATHOGENS (2007)
HIV integration site selection: Analysis by massively parallel pyrosequencing reveals association with epigenetic modifications
Gary P. Wang et al.
GENOME RESEARCH (2007)
LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration
Ming-Chieh Shun et al.
GENES & DEVELOPMENT (2007)
HIV-1 proviral DNA excision using an evolved recombinase
Indrani Sarkar et al.
SCIENCE (2007)
HIV-1 DNA Flap formation promotes uncoating of the pre-integration complex at the nuclear pore
Nathalie J. Arhel et al.
EMBO JOURNAL (2007)
In-Silico docking of HIV-1 integrase inhibitors reveals a novel drug type acting on an enzyme/DNA reaction intermediate
Andrea Savarino
RETROVIROLOGY (2007)
Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy
Terumasa Ikeda et al.
JOURNAL OF INFECTIOUS DISEASES (2007)
Suv39H1 and HP1γ are responsible for chromatin-mediated HIV-1 transcriptional silencing and post-integration latency
Isaure du Chene et al.
EMBO JOURNAL (2007)
Sustained induction of NF-kappa B is required for efficient expression of latent human immunodeficiency virus type 1
Samuel A. Williams et al.
JOURNAL OF VIROLOGY (2007)
The road to chromatin - nuclear entry of retroviruses
Youichi Suzuki et al.
NATURE REVIEWS MICROBIOLOGY (2007)
An essential role for LEDGF/p75 in HIV integration
Manuel Llano et al.
SCIENCE (2006)
HIV integration site selection: Targeting in macrophages and the effects of different routes of viral entry
Stephen D. Barr et al.
MOLECULAR THERAPY (2006)
Integration of human immunodeficiency virus type 1 in untreated infection occurs preferentially within genes
Hongbing Liu et al.
JOURNAL OF VIROLOGY (2006)
Retroviral DNA integration: Viral and cellular determinants of target- site selection
Mary K. Lewinski et al.
PLOS PATHOGENS (2006)
Chromosome territories -: a functional nuclear landscape
Thomas Cremer et al.
CURRENT OPINION IN CELL BIOLOGY (2006)
A role for LEDGF/p75 in targeting HIV DNA integration
A Ciuffi et al.
NATURE MEDICINE (2005)
Genome wide analysis of retroviral DNA integration
F Bushman et al.
NATURE REVIEWS MICROBIOLOGY (2005)
Acetylation of HIV-1 integrase by p300 regulates viral integration
A Cereseto et al.
EMBO JOURNAL (2005)
Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75
P Cherepanov et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)
Symmetrical base preferences surrounding HIV-1 and avian sarcoma/leukosis virus but not murine leukemia virus integration sites
AG Holman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences
RS Mitchell et al.
PLOS BIOLOGY (2004)
Capsid is a dominant determinant of retrovirus infectivity in nondividing cells
M Yamashita et al.
JOURNAL OF VIROLOGY (2004)
Resting CD4+ T cells from human immunodeficiency virus type I (HIV-1)-infected individuals carry integrated HIV-1 Genomes within actively transcribed host genes
YF Han et al.
JOURNAL OF VIROLOGY (2004)
LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells
G Maertens et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Transcription start regions in the human genome are favored targets for MLV integration
XL Wu et al.
SCIENCE (2003)
Recruitment of human cyclin T1 to nuclear bodies through direct interaction with the PML protein
A Marcello et al.
EMBO JOURNAL (2003)
HIV reproducibly establishes a latent infection after acute infection of T cells in vitro
A Jordan et al.
EMBO JOURNAL (2003)
HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells
P Cherepanov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Visualization of the intracellular behavior of HIV in living cells
D McDonald et al.
JOURNAL OF CELL BIOLOGY (2002)
HIV-1 integration in the human genome favors active genes and local hotspots
ARW Schröder et al.
CELL (2002)
Catalysis of cis/trans isomerization in native HIV-1 capsid by human cyclophilin A
DA Bosco et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
HIV integrase, a brief overview from chemistry to therapeutics
R Craigie
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Identification of in vivo DNA targets of chromatin proteins using tethered Dam methyltransferase
B van Steensel et al.
NATURE BIOTECHNOLOGY (2000)
Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells
DJ Hazuda et al.
SCIENCE (2000)
Lens epithelium-derived growth factor: Effects on growth and survival of lens epithelial cells, keratinocytes, and fibroblasts
DP Singh et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)