☆ 4.6 Review

An analysis of the nutritional effects of Schisandra chinensis components based on mass spectrometry technology

FRONTIERS IN NUTRITION (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Nutrition & Dietetics

Schisandrol A and gomisin N from Schisandra chinensis extract improve hypogonadism via anti-oxidative stress in TM3 Leydig cells

Jia Bak et al.

Summary: This study investigated the effects of Schisandra chinensis extract on testosterone deficiency and found that the extract and its compounds can inhibit oxidative stress and increase testosterone levels, indicating their potential therapeutic role.

NUTRITION RESEARCH AND PRACTICE (2023)

添加到收藏夹

Article Food Science & Technology

Application of a novel and green temperature-responsive deep eutectic solvent system to simultaneously extract and separate different polar active phytochemicals from Schisandra chinensis (Turcz.) Baill

Xin-Yu Yan et al.

Summary: A novel and green temperature-responsive deep eutectic solvent (TRDES) system was developed for the simultaneous extraction and separation of different polar active phytochemicals from Schisandra chinensis. Under optimal parameters, TRDES showed higher yields compared to conventional solvents for lignanoids and polysaccharides extraction. The separated compounds exhibited strong antioxidant activities. TRDES has the potential to be widely used for efficient extraction and separation of multi-polar components and has lower cost production from plants.

FOOD RESEARCH INTERNATIONAL (2023)

添加到收藏夹

Article Biochemistry & Molecular Biology

Microwave assisted free radical degradation of Schisandra polysaccharides: Optimization, identification and application

Xue-Qing Liu et al.

Summary: A sample preparation method based on microwave assisted free radical degradation (MFRD) was proposed to establish structural-fingerprinting of polysaccharides for quality assessment. The MFRD condition was optimized and the structures of the degradation products were analyzed. A low-polymerization compositional fingerprinting was successfully constructed using high-performance anion-exchange chromatography. Compared to conventional methods, MFRD significantly improves sample preparations and is applicable to various polysaccharide samples.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2023)

添加到收藏夹

Article Chemistry, Analytical

An alternative strategy based on ultra-high-performance supercritical fluid chromatography for full monosaccharide compositional analysis of polysaccharides in Schisandra chinensis fruits

Jia-Ning Gao et al.

Summary: In this study, an ultra-high-performance supercritical fluid chromatography technology with an unusual binary modifier is used to determine the monosaccharide compositions of natural polysaccharides. The method has the advantages of small consumption of organic solvent, safety, and being environmental-friendly.

JOURNAL OF SEPARATION SCIENCE (2023)

添加到收藏夹

Article Biochemistry & Molecular Biology

Do Rutin and Quercetin Retain Their Structure and Radical Scavenging Activity after Exposure to Radiation?

Natalia Rosiak et al.

Summary: The influence of ionizing radiation on the physicochemical properties of quercetin and rutin in the solid state was investigated. The results showed that irradiation caused the formation of a small number of free radicals, but did not change the chemical structure or antioxidant properties of the tested flavonoids. Spectroscopic and chromatographic analyses confirmed the radiostability of quercetin and rutin.

MOLECULES (2023)

添加到收藏夹

Article Agriculture, Dairy & Animal Science

Effects of Schisandra chinensis Polysaccharide-Conjugated Selenium Nanoparticles on Intestinal Injury in Mice

Hongxu Du et al.

Summary: This study synthesized SCP-conjugated selenium nanoparticles (SCP-Se NPs) and investigated their effect on intestinal injury. The results showed that SCP-Se NPs could effectively alleviate LPS-induced diarrhea, intestinal tissue injury, and tight junction destruction, and decrease the elevated inflammatory cytokine expression levels. SCP-Se NPs may serve as a good candidate for preventing and treating enteritis in the livestock and poultry industry.

ANIMALS (2023)

添加到收藏夹

Article Plant Sciences

Schisandrin C enhances cGAS-STING pathway activation and inhibits HBV replication

Jia Zhao et al.

Summary: This study aimed to investigate the therapeutic effect of the active components of Schisandra Chinensis on antiviral immunity and explore the underlying mechanism. It was found that these active components could promote the activation of the cGAS-STING signaling pathway and inhibit HBV replication. This study provides clues for the treatment of chronic hepatitis B and other infectious diseases.

JOURNAL OF ETHNOPHARMACOLOGY (2023)

添加到收藏夹

Article Chemistry, Applied

Dibenzocyclooctadiene lignans from the stems ofSchisandra sphaerandra

You-Min Ying et al.

Summary: Chemical investigation of the stems of medicinal plant Schisandra sphaerandra led to the discovery of a new lignan compound, along with 11 known lignans, with cytotoxic activity against triple-negative breast cancer cell lines MDA-MB-231 and HCC-1937. This study also identified the chemical structure of the new compound using comprehensive spectroscopic methods.

NATURAL PRODUCT RESEARCH (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Schisandrin A and B affect the proliferation and differentiation of neural stem cells

Ning-Ning Cai et al.

Summary: Schisandrin A and B have been found to enhance the proliferation of neural stem cells and promote neuronal differentiation. Particularly, Schisandrin B not only increases neurosphere formation, but also enhances the expression of related genes.

JOURNAL OF CHEMICAL NEUROANATOMY (2022)

添加到收藏夹

Review Plant Sciences

A comprehensive review of ethnopharmacology, phytochemistry, pharmacology, and pharmacokinetics of Schisandra chinensis (Turcz.) Baill. and Schisandra sphenanthera Rehd. et Wils.

Ke Yang et al.

Summary: Schisandra chinensis and Schisandra sphenanthera, known as bei-wuweizi and nan-wuweizi in Chinese respectively, are highly similar plants with traditional uses in Chinese medicine for treating various conditions. They have similar chemical compositions and pharmacological activities, with potential drug interactions due to their inhibitory effects on CYP3A and P-gp. Further research is needed to explore their traditional uses and differences for clinical applications.

JOURNAL OF ETHNOPHARMACOLOGY (2022)

添加到收藏夹

Article Spectroscopy

Rapid determination and origin identification of total polysaccharides contents in Schisandra chinensis by near-infrared spectroscopy

Lun Wu et al.

Summary: In this study, a classification model based on near-infrared spectroscopy and random forest method accurately distinguished three samples of Schisandra chinensis from different habitats and predicted polysaccharide contents effectively. The method showed high accuracy, stability, and applicability in identifying the origin of Schisandra chinensis and evaluating its quality. The results demonstrate the potential for near-infrared spectroscopy combined with chemometrics in fast and reliable analysis of herbal products.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2022)

添加到收藏夹

Article Plant Sciences

Schisandrol A, the main active ingredient of Schisandrae Chinensis Fructus, inhibits pulmonary fibrosis through suppression of the TGF- β signaling pathway as revealed by UPLC-Q-TOF/MS, network pharmacology and experimental verification

Zhenghua Wu et al.

Summary: This study identified the absorbed active ingredients and metabolites of Schisandra in rat plasma, and illuminated its biological mechanism of treatment for idiopathic pulmonary fibrosis through experimental and network pharmacology investigation.

JOURNAL OF ETHNOPHARMACOLOGY (2022)

添加到收藏夹

Article Endocrinology & Metabolism

Schisandrin B mitigates hepatic steatosis and promotes fatty acid oxidation by inducing autophagy through AMPK/mTOR signaling pathway

Li-Shan Yan et al.

Summary: This study found that Schisandrin B inhibits hepatic steatosis and promotes fatty acid oxidation (FAO) through the activation of autophagy via the AMPK/mTOR pathway. These findings provide new insights into the potential application of Schisandrin B in the management of non-alcoholic fatty liver disease (NAFLD).

METABOLISM-CLINICAL AND EXPERIMENTAL (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Schisandra rubriflora Fruit and Leaves as Promising New Materials of High Biological Potential: Lignan Profiling and Effect-Directed Analysis

Ewelina Sobstyl et al.

Summary: The effect-directed detection (EDD) was conducted to evaluate the pharmacological properties of Schisandra rubriflora fruit and leaves extracts. The results showed that both fruit and leaf extracts exhibited antioxidant activity, with stronger inhibition of lipase and tyrosinase by the leaf extracts, and slightly higher inhibition of alpha-glucosidase and acetylcholinesterase (AChE) by the fruit extract. UHPLC-MS/MS analysis indicated the presence of potential anti-dementia compounds in the bioactive fractions. Gomisin N, schisanhenol, gomisin G, schisandrin A, and gomisin O were the dominant compounds in the fruit extract.

MOLECULES (2022)

添加到收藏夹

Review Chemistry, Medicinal

Chemistry, pharmacokinetics, pharmacological activities, and toxicity of Quercitrin

Junren Chen et al.

Summary: This paper systematically reviews the natural sources, pharmacological activities, and roles of quercitrin in various diseases, as well as its pharmacokinetics, structure-activity relationship, and toxicity. The underlying molecular mechanisms of quercitrin in treating related diseases and the dose-effect relationships are discussed, along with the need for further high-quality studies to establish its clinical efficacy.

PHYTOTHERAPY RESEARCH (2022)

添加到收藏夹

Article Toxicology

Schisandrin A alleviates mycophenolic acid-induced intestinal toxicity by regulating cell apoptosis and oxidative damage

Yiyun Deng et al.

Summary: The active component Schisandrin A (Sch A) in Schisandra chinensis can protect intestinal epithelial cells from mycophenolic acid-induced damage, reducing oxidative stress and inhibiting the MAPK signaling pathway.

TOXICOLOGY MECHANISMS AND METHODS (2022)

添加到收藏夹

Article Plant Sciences

Integration of full-length transcriptomes and anthocyanin metabolite analysis for understanding fruit coloration mechanism in Schisandra chinensis

Haiyan Li et al.

Summary: This study investigated the coloration mechanism of Schisandra chinensis fruits using transcriptomics and metabolomics analyses. The key anthocyanin responsible for fruit reddening was identified as Cyanidin3-O-xyl-rutinoside. A large number of Unigenes were obtained through single-molecule real-time sequencing, and differentially expressed genes related to anthocyanin biosynthesis were identified. Furthermore, potential transcription factors involved in regulating anthocyanin biosynthesis were selected.

PHYSIOLOGY AND MOLECULAR BIOLOGY OF PLANTS (2022)

添加到收藏夹

Review Biochemistry & Molecular Biology

Enzymatically Modified Isoquercitrin: Production, Metabolism, Bioavailability, Toxicity, Pharmacology, and Related Molecular Mechanisms

Aleksandra Owczarek-Januszkiewicz et al.

Summary: This review summarizes the research on enzymatically modified isoquercitrin (EMIQ) to date, and presents its characteristics in terms of bioavailability, toxicity, biological properties, and molecular mechanisms, as well as its importance in food additives and dietary supplements.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Evaluation of the Antioxidant, Cytoprotective and Antityrosinase Effects of Schisandra chinensis Extracts and Their Applicability in Skin Care Product

Martyna Zagorska-Dziok et al.

Summary: The study evaluated the biological activity of aqueous Schisandra chinensis extracts in skin care products and found that they have a positive effect on keratinocyte growth and possess high antioxidant potential and strong tyrosinase inhibitory activity. Microwave-assisted extraction followed by heat reflux extraction was found to be the most effective method for extracting polyphenols.

MOLECULES (2022)

添加到收藏夹

Article Plant Sciences

Metabolic profiling on the analysis of different parts of Schisandra chinensis based on UPLC-QTOF-MS with comparative bioactivity assays

Jiushi Liu et al.

Summary: This study characterized the metabolites of different parts of Schisandra chinensis using a combination of a chemical database and the Progenesis QI informatics platform. The results showed that the roots had higher levels of active substances and biological activities, such as antioxidant and anti-inflammatory activities, compared to the fruit. These findings suggest that the plant roots could be a potential new medicinal source with better activity than traditional medicinal parts.

FRONTIERS IN PLANT SCIENCE (2022)

添加到收藏夹

Article Plant Sciences

A multidimensional strategy for uncovering comprehensive quality markers of Schisandra chinensis (Turcz.) Baill based on pharmacodynamics and chemical properties

Yiwen Zhang et al.

Summary: This study established a novel and multidimensional quality assessment approach for Traditional Chinese Medicines (TCMs) using Schisandra chinensis as an example, identifying comprehensive quality markers based on pharmacodynamics and chemical properties.

PHYTOMEDICINE (2022)

添加到收藏夹

Review Chemistry, Medicinal

Schisandraceae triterpenoids: A review of phytochemistry, bioactivities and synthesis

Yi-Qiang Zhang et al.

Summary: This review summarizes the research progress on triterpenoids from the Schisandraceae family, which are found to have diverse structures and various pharmacological activities. However, most of the studies are limited to in vitro experiments, and data on in vivo and toxicology are lacking.

FITOTERAPIA (2022)

添加到收藏夹

Article Immunology

?-Iso-cubebene attenuates neointima formation by inhibiting HMGB1-induced monocyte to macrophage differentiation via suppressing ROS production

Seung Eun Baek et al.

Summary: This study investigates the effects of alpha-Iso-cubebene (ICB) on HMGB1-induced monocyte-macrophage differentiation (MMD) and suggests that ICB has therapeutic potential for vascular inflammation with subsequent intimal hyperplasia related to vascular injury.

INTERNATIONAL IMMUNOPHARMACOLOGY (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Schisandrin C isolated from Schisandra chinensis fruits inhibits lipid accumulation by regulating adipogenesis and lipolysis through AMPK signaling in 3T3-L1 adipocytes

Miran Jang et al.

Summary: In this study, the lignans of Schisandra chinensis fruits were analyzed and evaluated for their inhibitory effects on triglyceride accumulation. The compound schisandrin C showed the strongest inhibition on TG levels during adipogenesis of 3T3-L1 cells. It decreased adipocyte differentiation and total lipid and TG contents, while down-regulating the expressions of adipogenic transcription factors. Additionally, schisandrin C increased AMPK phosphorylation and inhibited lipolysis-related genes, suggesting its potential for preventing obesity and metabolic diseases.

JOURNAL OF FOOD BIOCHEMISTRY (2022)

添加到收藏夹

Article Oncology

Gomisin A enhances the antitumor effect of paclitaxel by suppressing oxidative stress in ovarian cancer

Taiwei Wang et al.

Summary: The study demonstrated that Gomisin A (GA) as an effective component of Schisandra can inhibit multidrug resistance in tumor cells and enhance the therapeutic effect of paclitaxel (PTX) in ovarian cancer. By reducing reactive oxygen species (ROS) levels, GA promotes PTX-induced cell cycle arrest in ovarian cancer cells both in vitro and in vivo. This novel combination therapy of PTX with the ROS inhibitor GA may offer a promising strategy for ovarian cancer chemotherapy.

ONCOLOGY REPORTS (2022)

添加到收藏夹

Review Food Science & Technology

Recent Progress in the Study of Taste Characteristics and the Nutrition and Health Properties of Organic Acids in Foods

Yige Shi et al.

Summary: Organic acids can improve food flavor, maintain nutritional value, and extend shelf life. Detection methods, concentrations, taste characteristics, and nutritional properties of organic acids vary in different foods. Research on the role of organic acids in food is of great significance for quality control.

FOODS (2022)

添加到收藏夹

Review Chemistry, Medicinal

The Therapeutic Potential of Plant Polysaccharides in Metabolic Diseases

Xiao-Fang Wang et al.

Summary: Plant polysaccharides (PPS) composed of multiple monosaccharides have shown high safety and various pharmacological activities. Emerging evidence suggests that many PPS are beneficial for metabolic diseases, particularly cardiovascular disease, diabetes, obesity, and neurological diseases. This review introduces the characteristics and functional activities of representative PPS, discusses their pharmacological activity and mechanism of action in metabolic diseases, and provides directions for future research and development of PPS as potential drugs for the treatment of metabolic diseases.

PHARMACEUTICALS (2022)

添加到收藏夹

Article Environmental Sciences

Contamination of food crops by unintentionally released PCB 47, PCB 51 and PCB 68 in the vicinity of silicone production sites and their relevance for human health assessment

Katja Hombrecher et al.

Summary: Silicone rubber production has been found to unintentionally release PCBs, leading to investigations in these production sites. The use of a cross-linking agent called 2,4-DCBP can result in the emission and accumulation of PCB congeners in the environment. A method called dandelion screening was used to determine the presence and extent of PCB uptake in wild dandelion plants near production sites in Germany. The study found that PCB levels exceeded background levels at seven out of the nine sites, leading to mitigation measures being taken.

CHEMOSPHERE (2022)

添加到收藏夹

Review Dermatology

Acne vulgaris: new evidence in pathogenesis and future modalities of treatment

Neirita Hazarika

Summary: Acne vulgaris, a common chronic disorder affecting up to 85% of adolescents and young adults, still has gaps in our understanding despite existing knowledge. This article reviews emerging evidence in the complex pathogenesis of acne and outlines potential future therapies in its management.

JOURNAL OF DERMATOLOGICAL TREATMENT (2021)

添加到收藏夹

Article Biology

Gomisin L1, a Lignan Isolated from Schisandra Berries, Induces Apoptosis by Regulating NADPH Oxidase in Human Ovarian Cancer Cells

Young Hyun Ko et al.

Summary: The lignan gomisin L1 from Schisandra berries demonstrates antitumor activity in human ovarian cancer cells by inducing apoptotic cell death through regulation of intracellular ROS production via NOX.

LIFE-BASEL (2021)

添加到收藏夹

Article Chemistry, Applied

Structural characterization of a novel Schisandra polysaccharides and nutritional intervention in immunotoxicity to PCBs

Ting Zhao et al.

Summary: The newly discovered polysaccharide SCPP22 from Schisandra chinensis fruits was shown to have beneficial effects in reversing PCB126-induced immunosuppression, enhancing body weight, improving oxidative injury in immune organs, and stimulating cytokine production. Its mechanism of action involves regulating apoptosis-related proteins expression. Schisandra polysaccharides could potentially be used in functional food as a nutritional intervention ingredient.

CARBOHYDRATE POLYMERS (2021)

添加到收藏夹

Article Chemistry, Analytical

Rapid characterization of Schisandra species by using direct analysis in real time mass spectrometry

Yunlong Guo et al.

Summary: In this study, DART-Q-Orbitrap MS was utilized to analyze S. chinensis and S. sphenanthera samples, and differences between the two species were explored through partial least squares discriminant analysis based on the DART-MS data. Eight compounds contributing most to the sample classification were successfully selected and annotated, and the existence of the compound anwulignan at m/z 328.1656 was found to help differentiate between the two species. This study demonstrates the potential of DART-MS as a powerful analytical tool for rapid detection and discrimination of S. chinensis and S. sphenanthera, with applications in the quality assessment of Schisandra species and possibly other herbal medicines.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2021)

添加到收藏夹

Review Chemistry, Medicinal

Molecular mechanisms of anticancer effect of rutin

Amir Imani et al.

Summary: Rutin, a polyphenolic bioflavonoid, has been extensively studied for its antioxidant properties and pharmacological applications in cancer research due to its safety and minor side effects. In-vivo and in-vitro examinations have shown that rutin regulates various cellular signaling pathways to mediate its anticancer effects, making it a promising compound for cancer treatment.

PHYTOTHERAPY RESEARCH (2021)

添加到收藏夹

Article Medicine, Research & Experimental

Schizandrin A can inhibit non-small cell lung cancer cell proliferation by inducing cell cycle arrest, apoptosis and autophagy

Linhai Zhu et al.

Summary: This study demonstrates that Schizandrin A (SchA) can inhibit the viability and proliferation of non-small cell lung cancer (NSCLC) cells by inducing cell cycle arrest and apoptosis. Additionally, SchA partially induces autophagy, although it does not result in cytoprotective effects.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

The Antioxidant Phytochemical Schisandrin A Promotes Neural Cell Proliferation and Differentiation after Ischemic Brain Injury

Wentian Zong et al.

Summary: The study demonstrates that Schisandrin A enhances the proliferation and differentiation of neural progenitor cells, possibly by regulating Cdc42 to control cytoskeletal rearrangement and cell polarization, offering new hope for late recovery from stroke.

MOLECULES (2021)

添加到收藏夹

Article Plant Sciences

Raw and wine processed Schisandra chinensis attenuate anxiety like behavior via modulating gut microbiota and lipid metabolism pathway

Yonggui Song et al.

Summary: This study investigated the mechanism by which raw and wine processed Schisandra chinensis improve anxiety behavior through modulating gut microbiota, with results indicating that WSC had a greater effect on treating anxiety compared to SC.

JOURNAL OF ETHNOPHARMACOLOGY (2021)

添加到收藏夹

Article Medicine, Research & Experimental

Schisantherin A improves learning and memory abilities partly through regulating the Nrf2/Keap1/ARE signaling pathway in chronic fatigue mice

Huijiao Lin et al.

Summary: In this study, the effects of Schizantherin A (SCA) on learning and memory in a chronic fatigue mouse model were investigated. SCA was found to improve learning and memory capabilities by increasing antioxidant enzyme activities and reducing oxidative stress markers in hippocampal tissues. SCA treatment also modulated the protein expression levels of key factors in the Nrf2-Keap1-antioxidant response element pathway, leading to enhanced anti-oxidative and anti-apoptosis effects.

EXPERIMENTAL AND THERAPEUTIC MEDICINE (2021)

添加到收藏夹

Article Chemistry, Analytical

HPLC-MS/MS-Mediated Analysis of the Pharmacokinetics, Bioavailability, and Tissue Distribution of Schisandrol B in Rats

Dahu Liang et al.

Summary: Schisandrol B, a lignan isolated from dried Schisandra chinensis fruits, has been shown to have protective effects on the liver, heart, kidneys, and memory. A sensitive HPLC-MS/MS method was developed to measure Schisandrol B levels in rat plasma and tissues, allowing for assessment of its pharmacokinetics, oral bioavailability, and tissue distribution. The results showed promising pharmacokinetic profiles and tissue distribution patterns of Schisandrol B, providing valuable insights for future studies on its pharmacological and biological characteristics.

INTERNATIONAL JOURNAL OF ANALYTICAL CHEMISTRY (2021)

添加到收藏夹

Article Plant Sciences

Dibenzocyclooctadiene Lignans in Plant Parts and Fermented Beverages of Schisandra chinensis

Woo Sung Park et al.

Summary: A study analyzed the content of seven lignans in Schisandra chinensis fruit using HPLC-DAD, revealing that seeds had the highest content. The addition of oligosaccharide/white sugar to fermented beverages significantly increased lignan content.

PLANTS-BASEL (2021)

添加到收藏夹

Article Food Science & Technology

Natural Extracts as Inhibitors of Microorganisms and Lipid Oxidation in Emulsion Sausage during Storage

Jeeyeon Lee et al.

Summary: This study compared the antimicrobial and antioxidant activities of natural compounds to chemical additives in foods, particularly meats. Natural extracts showed excellent antibacterial and antioxidant properties, which can be used as natural preservatives in meat products such as emulsion sausages. Natural extract-treated sausages demonstrated a significant reduction in bacterial growth and oxidation compared to control sausages, highlighting their potential as effective natural preservatives.

FOOD SCIENCE OF ANIMAL RESOURCES (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Antioxidant Effects of Schisandra chinensis Fruits and Their Active Constituents

Dalia M. Kopustinskiene et al.

Summary: Schisandra chinensis fruits, their extracts, and bioactive compounds have potent antioxidant and mitoprotective effects, exerting anti-inflammatory, antiviral, anticancer, and anti-aging properties. The polyphenolic compounds in S. chinensis are responsible for its antioxidant activities, which play a significant role in protecting cells under normal and pathological conditions.

ANTIOXIDANTS (2021)

添加到收藏夹

Article Medicine, Research & Experimental

Schisandra chinensis polysaccharides prevent cardiac hypertrophy by dissociating thioredoxin-interacting protein/thioredoxin-1 complex and inhibiting oxidative stress

Xiaowen Shi et al.

Summary: The study demonstrated that the antioxidative effects of SCP in attenuating oxidative stress were mediated through the regulation of the TXNIP/Trx-1 pathway, potentially making TXNIP a therapeutic target for treating cardiac hypertrophy.

BIOMEDICINE & PHARMACOTHERAPY (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Low-polymerization compositional fingerprinting for characterization of Schisandra polysaccharides by hydrophilic interaction liquid chromatography-electrospray mass spectrometry

Xin Li et al.

Summary: A method utilizing HILIC-ESI-MS coupled with MAMA was proposed for discrimination and characterization of plant polysaccharides SCP and SSP. The study showed that LCF combined with PCA and HCA could effectively reflect structural differences and achieve rapid discrimination of SCP and SSP.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

添加到收藏夹

Article Cell Biology

Schisandrol A Attenuates Myocardial Ischemia/Reperfusion-Induced Myocardial Apoptosis through Upregulation of 14-3-3θ

Shuaishuai Gong et al.

Summary: Schisandrol A (SA) extracted from Schisandra chinensis has significant cardioprotective effects against myocardial ischemia/reperfusion (MI/R) injury and hypoxia/reoxygenation (H/R)-induced cardiomyocyte injury. The mechanisms may involve the inhibition of cardiomyocyte apoptosis through upregulation of 14-3-3 theta.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

Study on the Hepatoprotection of Schisandra chinensis Caulis Polysaccharides in Nonalcoholic Fatty Liver Disease in Rats Based on Metabolomics

Yanbo Feng et al.

Summary: The study demonstrated that Schisandra chinensis Caulis polysaccharides (SCPs) can alleviate the development of nonalcoholic fatty liver disease (NAFLD) in rats by regulating the expression of specific enzymes, leading to lower levels of harmful lipids in the serum.

FRONTIERS IN PHARMACOLOGY (2021)

添加到收藏夹

Review Food Science & Technology

ASSURED Point-of-Need Food Safety Screening: A Critical Assessment of Portable Food Analyzers

Safiye Jafari et al.

Summary: Standard methods for chemical food safety testing rely on mass spectrometry in official laboratories, but there is a demand for portable devices due to the need for sampling and expensive equipment. Recent technological advancements include smartphone-based, microfluidic chip-based, and paper-based devices, as well as the potential application of portable mass spectrometers in food testing.

FOODS (2021)

添加到收藏夹

Article Nutrition & Dietetics

Schisandrae Fructus ethanol extract attenuates particulate matter 2.5-induced inflammatory and oxidative responses by blocking the activation of the ROS-dependent NF-κB signaling pathway

Hyesook Lee et al.

Summary: The study revealed that the ethanol extract of Schisandrae Fructus has inhibitory effects on inflammation and oxidative stress induced by PM2.5, by regulating the NF-κB signaling pathway and ROS. This indicates that Schisandrae Fructus may serve as a potential functional substance to prevent PM2.5-induced inflammatory and oxidative damage.

NUTRITION RESEARCH AND PRACTICE (2021)

添加到收藏夹

Article Food Science & Technology

An extractive nanoelectrospray ionization-mass spectrometry method for Chinese herbal medicine authentication

Chia-Hsin Lee et al.

Summary: The EnESI-MS method allows for rapid identification of volatile compound mass spectra fingerprints of traditional Chinese medicine without sample pretreatment. It successfully differentiate between morphologically similar but therapeutically different medicinal herbs.

JOURNAL OF FOOD AND DRUG ANALYSIS (2021)

添加到收藏夹

Review Biotechnology & Applied Microbiology

Organic acids as antimicrobial food agents: applications and microbial productions

Hasan Bugra Coban

BIOPROCESS AND BIOSYSTEMS ENGINEERING (2020)

添加到收藏夹

Article Immunology

Schisandrin A protects against lipopolysaccharide-induced mastitis through activating Nrf2 signaling pathway and inducing autophagy

Dianwen Xu et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Exploring the protective effects of schizandrol A in acute myocardial ischemia mice by comprehensive metabolomics profiling integrated with molecular mechanism studies

Qiong Lai et al.

ACTA PHARMACOLOGICA SINICA (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Lignans and Terpenoids from the Leaves of Schisandra chinensis

Guo-Zhen Liu et al.

CHEMISTRY & BIODIVERSITY (2020)

添加到收藏夹

Review Food Science & Technology

Inhibitory effects of organic acids on polyphenol oxidase: From model systems to food systems

Lei Zhou et al.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2020)

添加到收藏夹

Article Microbiology

Antibacterial Effects of Schisandra chinensis Extract on Escherichia coli and its Applications in Cosmetic

S. Mei Cui et al.

CURRENT MICROBIOLOGY (2020)

添加到收藏夹

Review Biochemical Research Methods

Molecular mechanisms of probiotic prevention of antibiotic-associated diarrhea

Solomon A. Mekonnen et al.

CURRENT OPINION IN BIOTECHNOLOGY (2020)

添加到收藏夹

Article Plant Sciences

Effect of gomisin A on osteoblast differentiation in high glucose-mediated oxidative stress

Jyoti Shrestha Takanche et al.

PHYTOMEDICINE (2020)

添加到收藏夹

Review Cell Biology

A Comprehensive Review on Schisandrin B and Its Biological Properties

M. I. Nasser et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Schisandra rubriflora Plant Material and In Vitro Microshoot Cultures as Rich Sources of Natural Phenolic Antioxidants

Agnieszka Szopa et al.

ANTIOXIDANTS (2020)

添加到收藏夹

Article Chemistry, Analytical

Rapid analysis of nine lignans in Schisandra chinensis by supercritical fluid chromatography using diode array and mass spectrometric detection

Sevil Onay et al.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Rapid Mass Spectrometric Study of a Supercritical CO2-extract from Woody Liana Schisandra chinensis by HPLC-SPD-ESI-MS/MS

Mayya Razgonova et al.

MOLECULES (2020)

添加到收藏夹

Article Immunology

Antidepressant-like effects of Schisandrin on lipopolysaccharide-induced mice : Gut microbiota, short chain fatty acid and TLR4/NF-κB signaling pathway

Yingying Sun et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

Free Radicals as a Double-Edged Sword: The Cancer Preventive and Therapeutic Roles of Curcumin

Nehal Gupta et al.

MOLECULES (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Effects of Deacidification on Composition of Schisandra chinensis Ethanolic Extract and Studies on Acute Toxicity in Mice

Gaosheng Hu et al.

MOLECULES (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Purification, structural characterization, and cognitive improvement activity of a polysaccharides from Schisandra chinensis

Mengjie Xu et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

添加到收藏夹

Article Nutrition & Dietetics

Schisandrin B alleviates acute oxidative stress via modulation of the Nrf2/Keap1-mediated antioxidant pathway

Ying Wu et al.

APPLIED PHYSIOLOGY NUTRITION AND METABOLISM (2019)

添加到收藏夹

Article Chemistry, Applied

New lignan from the rattan stems of Schisandra chinensis

Bing-You Yang et al.

NATURAL PRODUCT RESEARCH (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

Effects of Schisandra chinensis polysaccharides on rats with antibiotic-associated diarrhea

Yuli Qi et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

添加到收藏夹

Article Plant Sciences

Polysaccharide of Schisandra Chinensis Fructus ameliorates cognitive decline in a mouse model of Alzheimer's disease

Mengjie Xu et al.

JOURNAL OF ETHNOPHARMACOLOGY (2019)

添加到收藏夹

Article Chemistry, Analytical

Application of characteristic fragment filtering with ultra high performance liquid chromatography coupled with high-resolution mass spectrometry for comprehensive identification of components in Schisandrae chinensis Fructus

Chanjuan Yu et al.

JOURNAL OF SEPARATION SCIENCE (2019)

添加到收藏夹

Review Nutrition & Dietetics

Potential of Schisandra chinensis (Turcz.) Baill. in Human Health and Nutrition: A Review of Current Knowledge and Therapeutic Perspectives

Adriana Nowak et al.

NUTRIENTS (2019)

添加到收藏夹

Article Pharmacology & Pharmacy

Schisandrin A Inhibits the IL-1β-Induced Inflammation and Cartilage Degradation via Suppression of MAPK and NF-κB Signal Pathways in Rat Chondrocytes

Chang Tu et al.

FRONTIERS IN PHARMACOLOGY (2019)

添加到收藏夹

Article Chemistry, Medicinal

Cyanidin 3-Rutinoside, an Anthocyanin Pigment of Schisandra chinensis Baill, Inhibits Allergic Inflammation

Yong-Deok Jeon et al.

JOURNAL OF MEDICINAL FOOD (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

Quality Evaluation of Wild and Cultivated Schisandrae Chinensis Fructus Based on Simultaneous Determination of Multiple Bioactive Constituents Combined with Multivariate Statistical Analysis

Shuyu Chen et al.

MOLECULES (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

Physicochemical properties, antioxidant activity and immunological effects in vitro of polysaccharides from Schisandra sphenanthera and Schisandra chinensis

Xiaoyi Chen et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

添加到收藏夹

Article Chemistry, Medicinal

Protective Effect of Schisandra chinensis Polysaccharides Against the Immunological Liver Injury in Mice Based on Nrf2/ARE and TLR4/NF-κB Signaling Pathway

Yingying Shan et al.

JOURNAL OF MEDICINAL FOOD (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

The Effect of Schisandra chinensis Baillon on Cross-Talk between Oxidative Stress, Endoplasmic Reticulum Stress, and Mitochondrial Signaling Pathway in Testes of Varicocele-Induced SD Rat

Keshab Kumar Karna et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Phenolic acid and flavonoid production in agar, agitated and bioreactor-grown microshoot cultures of Schisandra chinensis cv. Sadova No. 1-a valuable medicinal plant

Agnieszka Szopa et al.

JOURNAL OF BIOTECHNOLOGY (2019)

添加到收藏夹

Article Multidisciplinary Sciences

Schisandrin A protects intestinal epithelial cells from deoxynivalenol-induced cytotoxicity, oxidative damage and inflammation

Murphy L. Y. Wan et al.

SCIENTIFIC REPORTS (2019)

添加到收藏夹

Article Pharmacology & Pharmacy

Schisandrin C enhances mitochondrial biogenesis and autophagy in C2C12 skeletal muscle cells: potential involvement of anti-oxidative mechanisms

Jeong-Seok Kim et al.

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2018)

添加到收藏夹

Article Medicine, Research & Experimental

Sedative and hypnotic effects of Schisandrin B through increasing GABA/Glu ratio and upregulating the expression of GABAA in mice and rats

Ning Li et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

添加到收藏夹

Review Chemistry, Applied

A review of polysaccharides from Schisandra chinensis and Schisandra sphenanthera: Properties, functions and applications

Zijian Li et al.

CARBOHYDRATE POLYMERS (2018)

添加到收藏夹

Article Gastroenterology & Hepatology

Modeling NAFLD disease burden in China, France, Germany, Italy, Japan, Spain, United Kingdom, and United States for the period 2016-2030

Chris Estes et al.

JOURNAL OF HEPATOLOGY (2018)

添加到收藏夹

Article Chemistry, Analytical

Magnetic separation coupled with high-performance liquid chromatography-mass spectrometry for rapid separation and determination of lignans in Schisandra chinensis

Jishou Piao et al.

JOURNAL OF SEPARATION SCIENCE (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

Isolation, Structural Elucidation of Three New Triterpenoids from the Stems and Leaves of Schisandra chinensis (Turcz) Baill

Feng Qiu et al.

MOLECULES (2018)

添加到收藏夹

Review Cell Biology

Rutin as a Potent Antioxidant: Implications for Neurodegenerative Disorders

Adaze Bijou Enogieru et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)

添加到收藏夹

Article Medicine, Research & Experimental

Immunomodulatory effect of Schisandra polysaccharides in cyclophosphamide-induced immunocompromised mice

Jiahui Yu et al.

EXPERIMENTAL AND THERAPEUTIC MEDICINE (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

Gomisin N Alleviates Ethanol-Induced Liver Injury through Ameliorating Lipid Metabolism and Oxidative Stress

Arulkumar Nagappan et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

添加到收藏夹

Article Pharmacology & Pharmacy

Nrf2 in alcoholic liver disease

Jing Sun et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2018)

添加到收藏夹

Article Pharmacology & Pharmacy

Gomisin A Suppresses Colorectal Lung Metastasis by Inducing AMPK/p38-Mediated Apoptosis and Decreasing Metastatic Abilities of Colorectal Cancer Cells

Ji-Ye Kee et al.

FRONTIERS IN PHARMACOLOGY (2018)

添加到收藏夹

Review Chemistry, Analytical

On-line coupling of supercritical fluid extraction and chromatographic techniques

Andrea del Pilar Sanchez-Camargo et al.

JOURNAL OF SEPARATION SCIENCE (2017)

添加到收藏夹

Review Plant Sciences

Current knowledge of Schisandra chinensis (Turcz.) Baill. (Chinese magnolia vine) as a medicinal plant species: a review on the bioactive components, pharmacological properties, analytical and biotechnological studies

Agnieszka Szopa et al.

PHYTOCHEMISTRY REVIEWS (2017)

添加到收藏夹

Article Chemistry, Medicinal

Triterpenoids and lignans from the fruit of Schisandra sphenanthera

Ye Liu et al.

FITOTERAPIA (2017)

添加到收藏夹

Article Immunology

Attenuation of cyclosporine A induced nephrotoxicity by schisandrin B through suppression of oxidative stress, apoptosis and autophagy

Qiao Lai et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2017)

添加到收藏夹

Article Biochemistry & Molecular Biology

In Vitro Antioxidant activities and anti-diabetic effect of a polysaccharide from Schisandra sphenanthera in rats with type 2 diabetes

Jiamu Niu et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2017)

添加到收藏夹

Article Chemistry, Analytical

Study of organic acids in Schisandrae Chinensis Fructus after vinegar processing

Fangzhou Yin et al.

JOURNAL OF SEPARATION SCIENCE (2017)

添加到收藏夹

Article Biochemistry & Molecular Biology

Rapid Classification and Identification of Chemical Components of Schisandra Chinensis by UPLC-Q-TOF/MS Combined with Data Post-Processing

Shenshen Yang et al.

MOLECULES (2017)

添加到收藏夹

Article Medicine, Research & Experimental

Comparative effects of schisandrin A, B, and C on Propionibacterium acnes-induced, NLRP3 inflammasome activation-mediated IL-1β secretion and pyroptosis

Miaomiao Guo et al.

BIOMEDICINE & PHARMACOTHERAPY (2017)

添加到收藏夹

Review Medicine, Research & Experimental

Mechanisms of antidiabetic effects of flavonoid rutin

Ahmad Ghorbani

BIOMEDICINE & PHARMACOTHERAPY (2017)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Accumulation of dibenzocyclooctadiene lignans in agar cultures and in stationary and agitated liquid cultures of Schisandra chinensis (Turcz.) Baill

Agnieszka Szopa et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2016)

添加到收藏夹

Article Plant Sciences

Highly oxygenated triterpenoids from the roots of Schisandra chinensis and their anti-inflammatory activities

Qiu-Yan Song et al.

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2016)

添加到收藏夹

Article Agriculture, Multidisciplinary

Identification and analysis of anthocyanin components in fruit color variation in Schisandra chinensis

Jingjing Liao et al.

JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2016)

添加到收藏夹

Article Medicine, Research & Experimental

Biological effects of rutin on skin aging

Seong Jin Choi et al.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2016)

添加到收藏夹

Article Biochemistry & Molecular Biology

Enzymatic assays and molecular modeling studies of Schisandra chinensis lignans and phenolics from fruit and leaf extracts

Andrei Mocan et al.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2016)

添加到收藏夹

Article Plant Sciences

Antitussive activity of the Schisandra chinensis fruit polysaccharide (SCFP-1) in guinea pigs models

Shan Zhong et al.

JOURNAL OF ETHNOPHARMACOLOGY (2016)

添加到收藏夹

Review Cell Biology

Schisandrin B: A Double-Edged Sword in Nonalcoholic Fatty Liver Disease

Pou Kuan Leong et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)

添加到收藏夹

Article Food Science & Technology

Determination of lignans and phenolic components of Schisandra chinensis (Turcz.) Baill. using HPLC-ESI-ToF-MS and HPLC-online TEAC: Contribution of individual components to overall antioxidant activity and comparison with traditional antioxidant assays

Andrei Mocan et al.

JOURNAL OF FUNCTIONAL FOODS (2016)

添加到收藏夹

Article Toxicology

Schisandrol B Protects Against Acetaminophen-Induced Hepatotoxicity by Inhibition of CYP-Mediated Bioactivation and Regulation of Liver Regeneration

Yiming Jiang et al.

TOXICOLOGICAL SCIENCES (2015)

添加到收藏夹

Article Chemistry, Medicinal

Structure and bioactivity of triterpenoids from the stems of Schisandra sphenanthera

Cheng-Qin Liang et al.

ARCHIVES OF PHARMACAL RESEARCH (2014)

添加到收藏夹

Article Chemistry, Applied

Structure analysis of a bioactive heteropolysaccharide from Schisandra chinensis (Turcz.) Baill

Ting Zhao et al.

CARBOHYDRATE POLYMERS (2014)

添加到收藏夹

Article Biochemistry & Molecular Biology

Comparative Studies on Polyphenolic Composition, Antioxidant and Antimicrobial Activities of Schisandra chinensis Leaves and Fruits

Andrei Mocan et al.

MOLECULES (2014)

添加到收藏夹

Article Chemistry, Applied

Characterisation of proanthocyanidins from Schisandra chinensis seed coats by UPLC-QTOF/MS

Ting Yan et al.

NATURAL PRODUCT RESEARCH (2014)

添加到收藏夹

Review Pharmacology & Pharmacy

Role of Nrf2 in Oxidative Stress and Toxicity

Qiang Ma

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 53, 2013 (2013)

添加到收藏夹

Article Food Science & Technology

Antitumor and immunomodulatory activity of a water-soluble low molecular weight polysaccharide from Schisandra chinensis (Turcz.) Baill

Ting Zhao et al.

FOOD AND CHEMICAL TOXICOLOGY (2013)

添加到收藏夹

Article Food Science & Technology

Antioxidant and hepatoprotective effects of Schisandra chinensis pollen extract on CCl4-induced acute liver damage in mice

Ni Cheng et al.

FOOD AND CHEMICAL TOXICOLOGY (2013)

添加到收藏夹

Article Plant Sciences

Comprehensive chemical analysis of Schisandra chinensis by HPLC-DAD-MS combined with chemometrics

Haitao Liu et al.

PHYTOMEDICINE (2013)

添加到收藏夹

Article Biochemistry & Molecular Biology

In Vitro Cultures of Schisandra chinensis (Turcz.) Baill. (Chinese Magnolia Vine)-a Potential Biotechnological Rich Source of Therapeutically Important Phenolic Acids

Agnieszka Szopa et al.

APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY (2012)

添加到收藏夹

Article Biochemistry & Molecular Biology

Content and Color Stability of Anthocyanins Isolated from Schisandra chinensis Fruit

Chunhui Ma et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2012)

添加到收藏夹

Article Chemistry, Applied

Chemical composition and antioxidant activity of the essential oil of Schisandra chinensis fruits

Xiaoqiang Chen et al.

NATURAL PRODUCT RESEARCH (2012)

添加到收藏夹

Article Food Science & Technology

Structural Identification and Antioxidant Properties of Major Anthocyanin Extracted from Omija (Schizandra chinensis) Fruit

S. -H. Kim et al.

JOURNAL OF FOOD SCIENCE (2009)

添加到收藏夹

Review Plant Sciences

Pharmacology of Schisandra chinensis Bail.:: An overview of Russian research and uses in medicine

Alexander Panossian et al.

JOURNAL OF ETHNOPHARMACOLOGY (2008)

添加到收藏夹

Article Plant Sciences

Rubrisandrins A and B, lignans and related anti-HIV compounds from Schisandra rubriflora

Min Chen et al.

JOURNAL OF NATURAL PRODUCTS (2006)

添加到收藏夹

Review Chemistry, Multidisciplinary

Progress on the chemistry of dibenzocyclooctadiene lignans

JB Chang et al.

CHEMICAL REVIEWS (2005)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.