期刊
NATURE REVIEWS GENETICS
卷 17, 期 11, 页码 661-678出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrg.2016.112
关键词
-
资金
- European Horizon (H2020) MuG project [676556]
- Centre National de la Recherche Scientifique (CNRS)
- European Network of Excellence EpiGeneSys
- Agence Nationale de la Recherche (EpiDevoMath)
- Fondation pour la Recherche Medicale [DEI20151234396]
- INSERM/Plan Cancer Epigenetics and cancer program (grant acronym MMTT)
- Laboratory of Excellence EpiGenMed
- Fondation ARC pour la Recherche sur le Cancer
- Sir Henry Wellcome Postdoctoral Fellowship [WT100136MA]
Understanding how chromatin is organized within the nucleus and how this 3D architecture influences gene regulation, cell fate decisions and evolution are major questions in cell biology. Despite spectacular progress in this field, we still know remarkably little about the mechanisms underlying chromatin structure and how it can be established, reset and maintained. In this Review, we discuss the insights into chromatin architecture that have been gained through recent technological developments in quantitative biology, genomics and cell and molecular biology approaches and explain how these new concepts have been used to address important biological questions in development and disease.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据