Impact of Solidago virgaurea Extract on Biofilm Formation for ESBL-Pseudomonas aeruginosa: An In Vitro Model Study

Review Microbiology

Molecular mechanisms of antibiotic resistance revisited

Elizabeth M. Darby et al.

Summary: Antibiotic resistance is a global health emergency, and understanding the molecular mechanisms that bacteria use to resist antimicrobials is critical. Recent advances in research can aid in developing new antimicrobial therapies.

NATURE REVIEWS MICROBIOLOGY (2023)

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Article Microbiology

Antibacterial and Antibiofilm Effect of Unifloral Honeys against Bacteria Isolated from Chronic Wound Infections

Viktoria L. Balazs et al.

Summary: Hungarian honey types, particularly chestnut and linden honeys, have strong antibacterial activity and can disrupt bacterial membranes, making them potential alternatives for wound treatment.

MICROORGANISMS (2023)

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Article Infectious Diseases

Evaluation of Efflux-Mediated Resistance and Biofilm formation in Virulent Pseudomonas aeruginosa Associated with Healthcare Infections

Paul A. Akinduti et al.

Summary: This study explores the role of biofilm and efflux pump activities in high-level resistance of Pseudomonas aeruginosa strains in clinical infection. It finds that biofilm formers and strains with high efflux pump activity are associated with multidrug resistance. Furthermore, the study identifies specific risk factors for MDR-P. aeruginosa infection. The findings highlight the importance of addressing biofilm formation and efflux pump activity for clinical management and infection control.

ANTIBIOTICS-BASEL (2023)

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Article Veterinary Sciences

In vitro antibacterial and antifungal activities of extracts and fractions of leaves of Ricinus communis Linn against selected pathogens

Bedaso Kebede et al.

Summary: This study evaluated the antimicrobial activities of Ricinus communis leaf extracts and fractions. The results showed that the ethyl acetate fraction exhibited the best antimicrobial activity and bactericidal activity against all tested microorganisms.

VETERINARY MEDICINE AND SCIENCE (2022)

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Review Biochemistry & Molecular Biology

Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics

Shugang Qin et al.

Summary: This article comprehensively reviews the biophysical traits, behaviors, virulence factors, invasive regulators, and host defense patterns of P. aeruginosa, providing new directions for future research and contributing to the design of novel and/or alternative therapeutics to combat this clinically significant pathogen.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2022)

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Review Microbiology

Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis

Elio Rossi et al.

Summary: Genome sequencing reveals the phenotypic adaptation and transmission of P. aeruginosa in CF airways, but its limited potential in predicting chronic infection and adaptive state calls for linking phenotypic traits to genome sequences. The environmental conditions of CF lungs shape the genetic and phenotypic changes of P. aeruginosa, leading to its diversity and plasticity.

NATURE REVIEWS MICROBIOLOGY (2021)

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Article Pharmacology & Pharmacy

Is it Worth Combining Solidago virgaurea Extract and Antibiotics against Uropathogenic Escherichia coli rods? An In Vitro Model Study

Dorota Wojnicz et al.

Summary: The study found that European goldenrod extract can limit the survival of planktonic forms of bacteria and reduce biofilm formation, but when combined with antibiotics, it weakens their antibacterial activity and shortens the duration of post-antibiotic effects.

PHARMACEUTICS (2021)

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Article Biology