4.7 Article

Cost-Effectiveness Study of Double-Flange Voice Prostheses in the Treatment of Periprosthetic Leakage in Laryngectomized Patients

期刊

JOURNAL OF PERSONALIZED MEDICINE
卷 13, 期 7, 页码 -

出版社

MDPI
DOI: 10.3390/jpm13071064

关键词

voice prosthesis; tracheoesophageal speech; device life; laryngectomy; Provox XtraSeal; Provox Vega; head neck; cost effectiveness

向作者/读者索取更多资源

This study compares the duration and costs of Provox Vega (R) and Provox XtraSeal (R) voice prostheses in laryngectomized patients. The results show that Provox XtraSeal (R) has a longer duration, reduces the number of prosthesis replacements, saves costs, and is cost-effective.
Background: Tracheoesophageal speech with a voice prosthesis is considered the rehabilitation treatment of choice in laryngectomized patients. The main reasons for prosthesis failure are endoprosthetic leakage and periprosthetic leakage. The Provox XtraSeal (R) stent incorporates an additional double flange on the esophageal side to prevent periprosthetic leakage. The objective of this study is to compare the duration and costs of the Provox Vega (R) and Provox XtraSeal (R) prostheses used in these patients in a tertiary university hospital. Materials and methods: A prospective crossover case study of laryngectomees with Provox Vega (R) who underwent Provox XtraSeal (R) placement due to recurrent periprosthetic leaks and decreased theoretical prosthesis life. The duration and possible factors affecting voice prostheses were studied using Kaplan-Meier curves and Cox regression. A cost-effectiveness analysis was carried out from the perspective of the Spanish National Health System with an incremental cost-effectiveness calculation. Results: A total of 38 patients were recruited, 35 men and 3 women, with a mean age of 66.26 +/- 9.36 years old. Information was collected from 551 voice prostheses, 484 Provox Vega (R) and 68 Provox XtraSeal (R). The mean duration of Provox Vega (R) was 119.75 +/- 148.8 days and that of Provox XtraSeal (R) was 181.99 +/- 166.07 days (p = 0.002). The most frequent reason for replacement was endoprosthetic leakage in both groups: 283 (60.86%) in the case of Provox Vega (R) and 29 (48.33%) in that of XtraSeal (R) (p < 0.000). To obtain no cost differences (ICE similar to 0) between Provox Vega and Provox XtraSeal, the latter should cost EUR 551.63. Conclusions: The Provox XtraSeal (R) is a cost-effective option in patients with increased prosthesis replacements due to periprosthetic leakage, reducing the number of replacements, increasing the duration of the prosthesis, and providing savings compared to Provox Vega (R).

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.7
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据