4.8 Review

Advances In islet encapsulation technologies

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A prevascularized subcutaneous device-less site for islet and cellular transplantation

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Engineered VEGF-releasing PEG-MAL hydrogel for pancreatic islet vascularization

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Oxygen supply to encapsulated therapeutic cells

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Device design and materials optimization of conformal coating for islets of Langerhans

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REGENERATIVE MEDICINE (2014)

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Early Growth Response-2 Signaling Mediates Immunomodulatory Effects of Human Multipotential Stromal Cells

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STEM CELLS AND DEVELOPMENT (2014)

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Compliant 3D Microenvironment Improves β-Cell Cluster Insulin Expression Through Mechanosensing and β-Catenin Signaling

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TISSUE ENGINEERING PART A (2014)

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The effect of endothelial cells on hESC-derived pancreatic progenitors in a 3D environment

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The TheraCyte (TM) Device Protects Against Islet Allograft Rejection in Immunized Hosts

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Enhanced Oxygen Supply Improves Islet Viability in a New Bioartificial Pancreas

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Islet xenotransplantation from genetically engineered pigs

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Functional differences between aggregated and dispersed insulin-producing cells

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DIABETOLOGIA (2013)

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Mechanisms of mesenchymal stromal cell immunomodulation

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Characterization of a nanogland for the autotransplantation of human pancreatic islets

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Transplantation of human islets without immunosuppression

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PLG Scaffold Delivered Antigen-Specific Regulatory T Cells Induce Systemic Tolerance in Autoimmune Diabetes

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A Novel Monoclonal Antibody to CD40 Prolongs Islet Allograft Survival

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Regulatory T-cell therapy for transplantation: how many cells do we need?

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Improvement in Outcomes of Clinical Islet Transplantation: 1999-2010

Franca B. Barton et al.

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Treatment options for diabetes: Potential role of stem cells

Jamil Stanekzai et al.

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Preventing hypoxia-induced cell death in beta cells and islets via hydrolytically activated, oxygen-generating biomaterials

Eileen Pedraza et al.

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The impact of infection and tissue damage in solid-organ transplantation

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Islet Xenotransplantation Using Gal-Deficient Neonatal Donors Improves Engraftment and Function

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CD40-Specific Costimulation Blockade Enhances Neonatal Porcine Islet Survival in Nonhuman Primates

P. Thompson et al.

AMERICAN JOURNAL OF TRANSPLANTATION (2011)

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Advancing islet transplantation: from engraftment to the immune response

R. F. Gibly et al.

DIABETOLOGIA (2011)

Article Biochemistry & Molecular Biology

Cellular Hypoxia of Pancreatic β-Cells Due to High Levels of Oxygen Consumption for Insulin Secretion in Vitro

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JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

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Delivery of immunostimulatory monoclonal antibodies by encapsulated hybridoma cells

Juan Dubrot et al.

CANCER IMMUNOLOGY IMMUNOTHERAPY (2010)

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The hypoxia response pathway and beta-cell function

J. Cantley et al.

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Article Multidisciplinary Sciences

Proangiogenic scaffolds as functional templates for cardiac tissue engineering

Lauran R. Madden et al.

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Oxygen generating scaffolds for enhancing engineered tissue survival

Se Heang Oh et al.

BIOMATERIALS (2009)

Article Endocrinology & Metabolism

Safety and Viability of Microencapsulated Human Islets Transplanted Into Diabetic Humans

Bernard E. Tuch et al.

DIABETES CARE (2009)

Review Immunology

Following TRAIL's path in the immune system

Christina Falschlehner et al.

IMMUNOLOGY (2009)

Article Multidisciplinary Sciences

Embryonic pig pancreatic tissue for the treatment of diabetes in a nonhuman primate model

Gil Hecht et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Respiratory System

Attenuation of lipopolysaccharide-induced acute lung injury by treatment with IL-10

Chieh-Liang Wu et al.

RESPIROLOGY (2009)

Review Immunology

Pig-to-nonhuman primate islet xenotransplantation

Bernhard J. Hering et al.

TRANSPLANT IMMUNOLOGY (2009)

Article Biochemistry & Molecular Biology

Macrophage activation and polarization

Fernando Oneissi Martinez et al.

FRONTIERS IN BIOSCIENCE-LANDMARK (2008)

Article Clinical Neurology

Spheramine for treatment of Parkinson's disease

Natividad P. Stover et al.

NEUROTHERAPEUTICS (2008)

Review Immunology

Mesenchymal stem cells in health and disease

Antonio Uccelli et al.

NATURE REVIEWS IMMUNOLOGY (2008)

Article Immunology

Creating immune privilege: active local suppression that benefits friends, but protects foes

Andrew L. Mellor et al.

NATURE REVIEWS IMMUNOLOGY (2008)

Article Engineering, Biomedical

Oxygen producing biomaterials for tissue regeneration

Benjamin S. Harrison et al.

BIOMATERIALS (2007)

Article Surgery

Islet vasculature as a regulator of endocrine pancreas function

Nikiforos Ballian et al.

WORLD JOURNAL OF SURGERY (2007)

Article Biotechnology & Applied Microbiology

A theoretical study of oxygen transfer including cell necrosis for the design of a bioartificial pancreas

Jean-Luc Dulong et al.

BIOTECHNOLOGY AND BIOENGINEERING (2007)

Article Cell & Tissue Engineering

The effects of cell density and device arrangement on the behavior of macroencapsulated beta-cells

Kristen E. La Flamme et al.

CELL TRANSPLANTATION (2007)

Review Immunology

Antigen-specific tolerance strategies for the prevention and treatment of autoimmune disease

Stephen D. Miller et al.

NATURE REVIEWS IMMUNOLOGY (2007)

Article Biotechnology & Applied Microbiology

Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells

Kevin A. D'Amour et al.

NATURE BIOTECHNOLOGY (2006)

Article Medicine, General & Internal

International trial of the edmonton protocol for islet transplantation

A. M. James Shapiro et al.

NEW ENGLAND JOURNAL OF MEDICINE (2006)

Article Biochemistry & Molecular Biology

Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways

K Cardona et al.

NATURE MEDICINE (2006)

Article Cell & Tissue Engineering

Photosynthetic oxygen generator for bioartificial pancreas

K Bloch et al.

TISSUE ENGINEERING (2006)

Article Engineering, Biomedical

Evaluation of alginate purification methods:: Effect on polyphenol, endotoxin, and protein contamination

J Dusseault et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2006)

Article Biotechnology & Applied Microbiology

Efficient differentiation of human embryonic stem cells to definitive endoderm

KA D'Amour et al.

NATURE BIOTECHNOLOGY (2005)

Article Endocrinology & Metabolism

Five-year follow-up after clinical islet transplantation

EA Ryan et al.

DIABETES (2005)

Article Cardiac & Cardiovascular Systems

Cell-demanded liberation of VEGF121 from fibrin implants induces local and controlled blood vessel growth

M Ehrbar et al.

CIRCULATION RESEARCH (2004)

Review Medicine, General & Internal

Medical progress: Islet transplantation as a treatment for diabetes - A work in progress

RP Robertson

NEW ENGLAND JOURNAL OF MEDICINE (2004)

Article Endocrinology & Metabolism

Exercise induces hypoglycemia in rats with islet transplantation

A Omer et al.

DIABETES (2004)

Review Pharmacology & Pharmacy

Nanoporous microsystems for islet cell replacement

TA Desai et al.

ADVANCED DRUG DELIVERY REVIEWS (2004)

Article Surgery

Survival of microencapsulated adult pig islets in mice in spite of an antibody response

VF Duvivier-Kali et al.

AMERICAN JOURNAL OF TRANSPLANTATION (2004)

Article Medicine, General & Internal

Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen.

AMJ Shapiro et al.

NEW ENGLAND JOURNAL OF MEDICINE (2000)