4.7 Article

Epigenetic and transcriptional regulation of CCL17 production by glucocorticoids in arthritis

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Cell Biology

CCL17/TARC in autoimmunity and inflammation-not just a T-cell chemokine

Tanya J. Lupancu et al.

Summary: CCL17 is a chemokine that is upregulated in autoimmune and inflammatory diseases, as well as cancer. It acts as a chemoattractant for T cells through its interaction with CCR4, and may also play a role in other cell types. This review summarizes the biology of CCL17, its regulation, and its potential involvement in disease pathogenesis.

IMMUNOLOGY AND CELL BIOLOGY (2023)

Article Immunology

Inhibition of Histone H3 Lysine-27 Demethylase Activity Relieves Rheumatoid Arthritis Symptoms via Repression of IL6 Transcription in Macrophages

Zhan Zhao et al.

Summary: The histone demethylase inhibitor GSK-J4 has been found to alleviate symptoms of collagen-induced arthritis in a mouse model by regulating the transcription of critical cytokine genes through the epigenetic marker H3K27me3 in polarized macrophages.

FRONTIERS IN IMMUNOLOGY (2022)

Review Immunology

Targeting GM-CSF in inflammatory and autoimmune disorders

Adrian A. Achuthan et al.

Summary: GM-CSF is a growth factor that promotes the differentiation and proliferation of bone marrow progenitor cells and has diverse biological functions including inflammation and pain mediation. Experimental studies suggest that GM-CSF could be a potential target in various inflammatory and autoimmune disorders.

SEMINARS IN IMMUNOLOGY (2021)

Review Rheumatology

Pharmacological and non-pharmacological therapeutic strategies in difficult-to-treat rheumatoid arthritis: a systematic literature review informing the EULAR recommendations for the management of difficult-to-treat rheumatoid arthritis

Nadia M. T. Roodenrijs et al.

Summary: This systematic literature review highlights the lack of high-quality evidence on the treatment of patients with difficult-to-treat rheumatoid arthritis. The effectiveness of biologic/targeted synthetic DMARDs decreased in patients who had failed multiple previous treatments, but non-pharmacological interventions showed potential for improving non-inflammatory complaints and self-management.

RMD OPEN (2021)

Review Immunology

GM-CSF in inflammation

John A. Hamilton

JOURNAL OF EXPERIMENTAL MEDICINE (2020)

Article Orthopedics

Targeting GM-CSF for collagenase-induced osteoarthritis pain and disease in mice

K. M-C Lee et al.

OSTEOARTHRITIS AND CARTILAGE (2020)

Article Immunology

CCL17 in Inflammation and Pain

Kevin M-C Lee et al.

JOURNAL OF IMMUNOLOGY (2020)

Review Immunology

GM-CSF: A Promising Target in Inflammation and Autoimmunity

Kevin M. C. Lee et al.

IMMUNOTARGETS AND THERAPY (2020)

Article Rheumatology

IL-23 in arthritic and inflammatory pain development in mice

Kevin M. -C. Lee et al.

ARTHRITIS RESEARCH & THERAPY (2020)

Article Rheumatology

Pharmacodynamic biomarkers and differential effects of TNF- and GM-CSF-targeting biologics in rheumatoid arthritis

Xiang Guo et al.

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES (2019)

Article Biochemistry & Molecular Biology

Epigenetic and transcriptional regulation of IL4-induced CCL17 production in human monocytes and murine macrophages

Amy T. Hsu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2018)

Article Cell Biology

Glucocorticoids promote apoptosis of proinflammatory monocytes by inhibiting ERK activity

Adrian Achuthan et al.

CELL DEATH & DISEASE (2018)

Article Rheumatology

CCL17 blockade as a therapy for osteoarthritis pain and disease

Ming-Chin Lee et al.

ARTHRITIS RESEARCH & THERAPY (2018)

Article Medicine, Research & Experimental

TNF and granulocyte macrophage-colony stimulating factor interdependence mediates inflammation via CCL17

Andrew D. Cook et al.

JCI INSIGHT (2018)

Editorial Material Rheumatology

Choosing New Targets for Rheumatoid Arthritis Therapeutics: Too Interesting to Fail?

Iain B. McInnes et al.

ARTHRITIS & RHEUMATOLOGY (2017)

Review Biochemistry & Molecular Biology

Modulation of gene expression dynamics by co-transcriptional histone methylations

Hyeonju Woo et al.

EXPERIMENTAL AND MOLECULAR MEDICINE (2017)

Article Mathematical & Computational Biology

Correcting gene expression data when neither the unwanted variation nor the factor of interest are observed

Laurent Jacob et al.

BIOSTATISTICS (2016)

Review Pharmacology & Pharmacy

Long-term side effects of glucocorticoids

Merih Oray et al.

EXPERT OPINION ON DRUG SAFETY (2016)

Article Medicine, Research & Experimental

Granulocyte macrophage colony-stimulating factor induces CCL17 pro uction via IRF4 to mediate inflammation

Adrian Achuthan et al.

JOURNAL OF CLINICAL INVESTIGATION (2016)

Article Pharmacology & Pharmacy

Anti-inflammatory glucocorticoids: Changing concepts

Robert Newton

EUROPEAN JOURNAL OF PHARMACOLOGY (2014)

Article Multidisciplinary Sciences

Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia

Panagiotis Ntziachristos et al.

NATURE (2014)

Article Rheumatology

Granulocyte-macrophage colony-stimulating factor is a key mediator in inflammatory and arthritic pain

Andrew D. Cook et al.

ANNALS OF THE RHEUMATIC DISEASES (2013)

Review Genetics & Heredity

Human housekeeping genes, revisited

Eli Eisenberg et al.

TRENDS IN GENETICS (2013)

Article Oncology

GM-CSF enhances tumor invasion by elevated MMP-2,-9, and-26 expression

Claudia M. Gutschalk et al.

CANCER MEDICINE (2013)

Article Mathematical & Computational Biology

Using control genes to correct for unwanted variation in microarray data

Johann A. Gagnon-Bartsch et al.

BIOSTATISTICS (2012)

Article Biochemistry & Molecular Biology

Gene networking and inflammatory pathway analysis in a JMJD3 knockdown human monocytic cell line

Nando Dulal Das et al.

CELL BIOCHEMISTRY AND FUNCTION (2012)

Article Biotechnology & Applied Microbiology

Mavrilimumab, a human monoclonal GM-CSF receptor-α antibody for the management of rheumatoid arthritis: a novel approach to therapy

Jagdish R. Nair et al.

EXPERT OPINION ON BIOLOGICAL THERAPY (2012)

Article Immunology

Defining GM-CSF- and Macrophage-CSF Dependent Macrophage Responses by In Vitro Models

Derek C. Lacey et al.

JOURNAL OF IMMUNOLOGY (2012)

Article Biochemistry & Molecular Biology

Molecular mechanism of Jmjd3-mediated interleukin-6 gene regulation in endothelial cells underlying spinal cord injury

Kwanghyun Lee et al.

JOURNAL OF NEUROCHEMISTRY (2012)

Review Cell Biology

Molecular mechanisms and potential functions of histone demethylases

Susanne Marije Kooistra et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)

Article Multidisciplinary Sciences

X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner

G. Grant Welstead et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Review Rheumatology

Prostaglandins and Rheumatoid Arthritis

Mohammad Javad Fattahi et al.

ARTHRITIS (2012)

Article Immunology

Annexin A1 and glucocorticoids as effectors of the resolution of inflammation

Mauro Perretti et al.

NATURE REVIEWS IMMUNOLOGY (2009)

Article Biochemistry & Molecular Biology

Dexamethasone destabilizes cyclooxygenase 2 mRNA by inhibiting mitogen-activated protein kinase p38

M Lasa et al.

MOLECULAR AND CELLULAR BIOLOGY (2001)