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The forgotten art of cold therapeutic properties in cancer: A comprehensive historical guide

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ISCIENCE
卷 26, 期 7, 页码 -

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CELL PRESS
DOI: 10.1016/j.isci.2023.107010

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Cold therapy, a powerful therapeutic approach that has been used for centuries, has been largely forgotten in modern medicine. This review explores its history and potential application in treating various diseases, including cancer, through techniques like cryoablation, cryotherapy, cryoimmunotherapy, cryothalectomy, and cryogen agent delivery. Although clinical trials are limited, recent research shows promising results in experimental animal cancer models, highlighting the significance of further investigation.
Cold therapy has been used for centuries, from Julius Caesar to Mohandas Gandhi, as a potent therapeutic approach. However, it has been largely forgotten in modern medicine. This review explores the history of cold therapy and its potential application as a therapeutic strategy against various diseases, including cancer. We examine the different techniques of cold exposure and the use of other therapeutical approaches, such as cryoablation, cryotherapy, cryoimmunotherapy, cryothalectomy, and delivery of cryogen agents. While clinical trials using cold therapy for cancer treatment are still limited, recent research shows promising results in experimental animal cancer models. This area of research is becoming increasingly significant and warrants further investigation.

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