The First Case of Fusarium falciforme Eumycetoma in Sudan and an Extensive Literature Review about Treatment Worldwide

Article Dermatology

Using a Madurella mycetomatis-specific PCR on grains obtained via non-invasive fine-needle aspirated material is more accurate than cytology

Emmanuel Edwar Siddig et al.

Summary: PCR performed on ultrasound-guided fine-needle aspiration (US-FNA) material has similar sensitivity and specificity as PCR performed on deep-seated biopsies.

MYCOSES (2023)

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Editorial Material Plant Sciences

First Report of Fusarium falciforme Causing Root Rot of Soybean (Glycine max) in Henan, China

F. Xu et al.

PLANT DISEASE (2023)

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Editorial Material Plant Sciences

First Report of Fusarium falciforme Causing Basal Rot of Onion (Allium cepa) in India

K. Sarwadnya et al.

PLANT DISEASE (2023)

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Editorial Material Plant Sciences

First Report of Tobacco Root Rot Caused by Fusarium falciforme in China

Rui Qiu et al.

PLANT DISEASE (2023)

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Article Medicine, General & Internal

Cutaneous tuberculosis of the foot clinically mimicking mycetoma: A case report

Ayman Ahmed et al.

Summary: In resource-limited settings like Sudan, where diagnostic and surveillance capacities are limited and several dermal diseases with similar clinical presentations are endemic, caution must be taken. Cutaneous tuberculosis (CTB), caused by Mycobacterium tuberculosis, is a rare infection that can present with atypical clinical manifestations resembling other neglected skin diseases. A comprehensive diagnostic approach involving clinical examination and laboratory investigations, including microbial culture, histopathological, and molecular examinations, is necessary for definitive diagnosis. In this article, we report a case of CTB initially misidentified clinically as mycetoma.

CLINICAL CASE REPORTS (2023)

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Article Medicine, General & Internal

Guillain-Barre syndrome associated with COVID-19 infection: A case series

Ayman Ahmed et al.

Summary: In this study, we presented a series of six patients with Guillain-Barre syndrome associated with COVID-19 infection, confirmed by RT-PCR. The report discusses laboratory investigation, case management, clinical presentation, and outcomes for each case. This is the first case series of COVID-19-associated GBS cases in Sudan.

CLINICAL CASE REPORTS (2023)

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Article Infectious Diseases

Sudden emergence and spread of cutaneous larva migrans in Sudan: A case series calls for urgent actions

Ayman Ahmed et al.

Summary: Cutaneous larva migrans (CLM) is a self-limiting parasitic skin disease caused by zoonotic hookworm. It commonly occurs in tropical and subtropical regions where people are often infected by contaminated places. The disease is often underestimated due to its self-limiting nature.

IDCASES (2023)

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Article Parasitology

The developed molecular biological identification tools for mycetoma causative agents: An update

Emmanuel Edwar Siddig et al.

Summary: Mycetoma can be caused by bacteria or fungi, resulting in actinomycetoma or eumycetoma. Molecular techniques, such as MALDI-TOF MS and DNA sequencing, enable rapid and accurate identification of causative organisms for guiding patient management and treatment.

ACTA TROPICA (2022)

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Editorial Material Plant Sciences

First Report of Fusarium falciforme (FSSC 3+4) Causing Rot of Industrial Hemp (Cannabis sativa) in California

K. R. Paugh et al.

PLANT DISEASE (2022)

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Article Infectious Diseases

Detection of multiple mycetoma pathogens using fungal metabarcoding analysis of soil DNA in an endemic area of Sudan

Hiroki Hashizume et al.

Summary: This study used DNA metabarcoding to identify fungal species causing mycetoma from soil samples. The method was able to detect the presence of multiple mycetoma-causative fungi and can contribute to accurate diagnosis and geographical mapping.

PLOS NEGLECTED TROPICAL DISEASES (2022)

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Article

An unusual cause of eumycetoma – Fusarium solani keratoplasticum

C. Correia et al.

Actas Dermo-Sifiliograficas (2022)

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Article Medicine, Research & Experimental

The Promotion and Development of One Health at Swiss TPH and Its Greater Potential

Jakob Zinsstag et al.

Summary: One Health, as an integrated health concept, has become an essential part of health research and development. It overlaps with other integrated approaches to health and considers patients and populations in their social-ecological context. One Health has gained significant political, institutional, and operational support, and is increasingly being incorporated into international health legislation. The Swiss Tropical and Public Health Institute has contributed to the development of One Health with early mentions in biomedical literature, and has explored its theoretical and methodological foundations as well as its potential as an integrated approach.

DISEASES (2022)

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Letter Immunology

Hepatitis E Virus Outbreak among Tigray War Refugees from Ethiopia, Sudan

Ayman Ahmed et al.

Summary: This study reports hepatitis E virus (HEV) outbreaks among Ethiopian refugees in Sudan from June 2021 to February 2022. Out of 1,589 cases of acute jaundice syndrome, 64% were confirmed to be HEV infection using PCR. Implementing vaccination, water, sanitation, and hygiene programs may reduce the risk of HEV outbreaks.

EMERGING INFECTIOUS DISEASES (2022)

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Article Public, Environmental & Occupational Health

The role of integrated programs in the prevention of COVID-19 in a humanitarian setting

Yousif Ali et al.

Summary: In the war-torn humanitarian region of South Kordofan, Sudan, integrated programs and health education activities successfully prevented the local spread of COVID-19, leading to advancements in healthcare services and response capacities.

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE (2022)

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Article Microbiology

The Emergence of Rift Valley Fever in Gedaref State Urges the Need for a Cross-Border One Health Strategy and Enforcement of the International Health Regulations

Ayman Ahmed et al.

Summary: The study identified the emergence of Rift Valley fever virus for the first time in Gedaref state, Sudan, highlighting the potential threat to public health in the region and countries importing animals or animal products from East Africa. The study suggests implementing a one health strategy with an early warning surveillance and response system to prevent the spread of the disease in the area.

PATHOGENS (2021)

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Article Microbiology

Eumycetoma Medical Treatment: Past, Current Practice, Latest Advances and Perspectives

Emmanuel Edwar Siddig et al.

Summary: Mycetoma, a neglected tropical disease prevalent in Africa, is characterized by a prolonged disease duration and low cure rate. Effective management of eumycetoma depends on accurate diagnosis, identification of the causative agent, and evaluating susceptibility to available drugs. The review discusses currently available antifungal agents and optimizing newly developed antifungals for potential second-line treatment of eumycetoma.

MICROBIOLOGY RESEARCH (2021)

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Article Mycology

Eumycetoma of the Foot due to Fusarium solani in a Person with Diabetes Mellitus: Report of a Case and Review of Literature

Liza Das et al.

Summary: The case study describes a diabetic patient with pedal eumycetoma caused by Fusarium solani sensu stricto treated with surgical excision and voriconazole therapy, resulting in significant improvement and nearly complete resolution of the lesion and sinus obliteration.

MYCOPATHOLOGIA (2021)

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Review Parasitology