期刊
NATURE NEUROSCIENCE
卷 20, 期 1, 页码 20-23出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nn.4452
关键词
-
资金
- National Institutes of Health [R01 NS098370, R01 NS089795]
Postnatal and adult neurogenesis are region- and modality specific, but the significance of developmentally distinct neuronal populations remains unclear. We demonstrate that chemogenetic inactivation of a subset of forebrain and olfactory neurons generated at birth disrupts responses to an aversive odor. In contrast, novel appetitive odor learning is sensitive to inactivation of adult-born neurons, revealing that developmentally defined sets of neurons may differentially participate in hedonic aspects of sensory learning.
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