☆ 4.6 Article

Charge transfer based green spectrophotometric method to determine remogliflozin etabonate applying response surface methodology supported with computational studies in pharmaceutical formulations

SUSTAINABLE CHEMISTRY AND PHARMACY (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Biochemical Research Methods

Stability-Indicating HPTLC Method for Determination of Remogliflozin Etabonate and Vildagliptin in Tablets

Gandhimathi Muruganathan et al.

Summary: A sensitive, selective, precise and stability-indicating HPTLC method was developed for simultaneous estimation of remogliflozin etabonate and vildagliptin and their degradation products. The method showed good separation on a silica gel G60F(254) pre-coated TLC plate using methanol:ethyl acetate:toluene:ammonia (1.5:4:4.5:0.1, v/v/v/v) as mobile phase and detection at 212 nm. Degradation studies in various stress conditions were conducted and the method also met the validation requirements by ICH. The method was successfully applied to tablets without interference from excipients and was considered highly selective.

JOURNAL OF CHROMATOGRAPHIC SCIENCE (2023)

添加到收藏夹

Article Chemistry, Analytical

Application of Box-Behnken design combined response surface methodology to optimize HPLC and spectrophotometric techniques for quantifying febuxostat in pharmaceutical formulations and spiked wastewater samples

Sk Manirul Haque et al.

Summary: This study developed visible spectrophotometry and high-performance liquid chromatography (HPLC) methods for quantitating febuxostat. The methods showed good accuracy and precision through optimization of reaction conditions and the chromatographic process.

MICROCHEMICAL JOURNAL (2023)

添加到收藏夹

Article Spectroscopy

Response surface methodology combined Box-Behnken design optimized green kinetic spectrophotometric and HPLC methods to quantify angiotensin receptor blocker valsartan in pharmaceutical formulations

S. K. Manirul Haque et al.

Summary: The high-performance liquid chromatographic (HPLC) and kinetic spectrophotometric methods were established for the determination of valsartan (VAL) in pharmaceutical formulations. The spectrophotometric procedures utilized different strategies to evaluate the VAL content, and the HPLC procedure was optimized using response surface methodology (RSM) and Box-Behnken design (BBD). Both methods showed excellent accuracy and precision, and were validated according to International Conference on Harmonization (ICH) guidelines. The analytical Eco-Scale score demonstrated that these green methods were a better option for VAL quantification.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2023)

添加到收藏夹

Article Chemistry, Analytical

Stability Indicating Method for the Assay of Remogliflozin Etabonate and its Related Substances by RP-HPLC

Ramji Lal Yadav et al.

Summary: Simple, accurate, precise and stable HPLC methods were developed and validated for the determination of related substances and assay content of Remogliflozin etabonate (RME). The optimization of chromatographic conditions and the use of specific parameters ensured reliable and consistent results. The method was successfully validated according to established guidelines, demonstrating its suitability for routine analysis of RME.

ANALYTICAL CHEMISTRY LETTERS (2023)

添加到收藏夹

Article Multidisciplinary Sciences

Validated Kinetic Spectrophotometric Methods to Optimize Robustness Study with Youden Factorial Combinations to Determine Repaglinide Using Response Surface Methodology via Box-Behnken Design

S. K. Manirul Haque

Summary: The response surface methodology combined with Box-Behnken design was successfully applied to enhance the kinetic spectrophotometric methods for the determination of repaglinide in pharmaceutical preparations. The optimization of key independent variables and the establishment of a significant model were achieved through analysis of variance. The method was validated using Youden's robustness test and proved to be accurate for determining repaglinide in various samples.

ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING (2023)

添加到收藏夹

Article Chemistry, Analytical

Experimental Design Approach for Quantitative Expressions of Simultaneous Quantification of Two Binary Formulations Containing Remogliflozin and Gliptins by RP-HPLC

Mahesh Attimarad et al.

Summary: The aim of this study was to develop a fast RP-HPLC method for simultaneous measurement of two antidiabetic formulations under identical experimental conditions. The optimized method showed good precision, accuracy, and robustness. The findings demonstrated that experimental design can be successfully used to optimize chromatographic conditions with fewer runs.

SEPARATIONS (2022)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

The current role of sodium-glucose cotransporter 2 inhibitors in type 2 diabetes mellitus management

Bo Xu et al.

Summary: This article examines the clinical benefit, safety, and tolerability of the four SGLT2 inhibitors approved by the US FDA for the treatment of type 2 diabetes mellitus. SGLT2 inhibitors reduce hyperglycemia by increasing urinary glucose excretion and improving beta-cell function. Early clinical trials have shown their beneficial effects with acceptable safety and excellent tolerability.

CARDIOVASCULAR DIABETOLOGY (2022)

添加到收藏夹

Article Education, Scientific Disciplines

Rapid Simultaneous Quantitative Analysis of Hypoglycemic agents by RP HPLC: Development, Validation and Application to Medicine

Mahesh Attimarad et al.

Summary: A simple and rapid RP-HPLC method was developed and validated for the quality control of a new formulation containing vildagliptin and remogliflozin. The method showed satisfactory linearity and accuracy, and was proven to be robust. It can be effectively used for the simultaneous quantification of vildagliptin and remogliflozin in the formulation.

INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH (2022)

添加到收藏夹

Article Chemistry, Physical

Box-Behnken experimental design for optimizing the HPLC method to determine hydrochlorothiazide in pharmaceutical formulations and biological fluid

S. K. Manirul Haque

Summary: An isocratic HPLC method was developed to quantify hydrochlorothiazide (HCT) and its impurities (A, B, C). Response surface methodology combined with Box-Behnken design was used to optimize the factors affecting chromatographic separation. The experimentally derived model was validated and found to be significant.

JOURNAL OF MOLECULAR LIQUIDS (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Crystal Structure, Topology, DFT and Hirshfeld Surface Analysis of a Novel Charge Transfer Complex (L3) of Anthraquinone and 4-{[(anthracen-9-yl)meth-yl] amino}-benzoic Acid (L2) Exhibiting Photocatalytic Properties: An Experimental and Theoretical Approach

Adeeba Ahmed et al.

Summary: A new donor-acceptor complex, L3, was synthesized using a facile route. The complex showed good crystallinity and thermal stability, and exhibited efficient photocatalytic activity for dye degradation. Molecular docking results also suggested potential biological applications for the complex.

MOLECULES (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

An Experimental Design Approach to Quantitative Expression for Quality Control of a Multicomponent Antidiabetic Formulation by the HILIC Method

Mahesh Attimarad et al.

Summary: A rapid and reproducible hydrophilic liquid chromatography (HILIC) method was developed for the simultaneous determination of remogliflozin etabonate (RE), vildagliptin (VD), and metformin (MF). The method was optimized using a central composite experimental design and validated according to ICH guidelines. The method showed excellent linearity and accuracy, and can be used for the quality assurance of pharmaceutical preparations.

MOLECULES (2022)

添加到收藏夹

Article Spectroscopy

Optimized Box-Behnken experimental design based response surface methodology and Youden's robustness test to develop and validate methods to determine nateglinide using kinetic spectrophotometry

S. K. Manirul Haque

Summary: Selective and straightforward kinetic spectrophotometric methods were developed for the quantification of nateglinide (NTG) in pharmaceutical dosage forms. The methods were optimized using experimental design and response surface methodology, and validated according to international guidelines. Robustness testing demonstrated the reproducibility and adaptability of the methods.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2022)

添加到收藏夹

Article Medicine, General & Internal

SGLT2 Inhibitors in Type 2 Diabetes Mellitus and Heart Failure-A Concise Review

Daria M. Keller et al.

Summary: SGLT2 inhibitors not only show excellent performance in improving glycemic control, but also have a positive impact on cardiovascular and renal outcomes. New guidelines recommend SGLT2 inhibitors as first-line treatment for heart failure patients, bringing new hope for the treatment of heart failure patients.

JOURNAL OF CLINICAL MEDICINE (2022)

添加到收藏夹

Article Pharmacology & Pharmacy

Simple and Sensitive RP-HPLC and UV Spectroscopic Methods for the Determination of Remogliflozin Etabonate in Pure and Pharmaceutical Formulations

Nandeesha Itigimatha et al.

Summary: Simple, accurate, reproducible, and precise reverse phase-high performance liquid chromatography (RP-HPLC) and ultraviolet (UV) spectroscopic methods have been developed for the determination of remogliflozin etabonate (RMZ) in bulk and dosage forms.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES (2022)

添加到收藏夹

Article Optics

Exploring microstructural, optical, electrical, and DFT/TD-DFT studies of boron subphthalocyanine chloride for renewable energy applications

A. M. Hassanien et al.

Summary: The microstructural, optical, and electrical properties of boron subphthalocyanine chloride (B-SubPcCl) were investigated for potential energy applications. Various techniques, including FE-SEM, K-M function, and spectrophotometric measurements, were used to analyze the surface morphology, structural nature, and optical characteristics of B-SubPcCl thin films. Heterojunction diodes of B-SubPcCl/n-Si were successfully fabricated and their electrical parameters were determined through current-voltage measurements. The complex dielectric functions and important parameters of B-SubPcCl were also studied using DFT/TD-DFT calculations.

OPTIK (2022)

添加到收藏夹

Article Chemistry, Physical

Supramolecular charge-transfer complex generated by the interaction between tin(II) 2,3-naphtalocyanine as a donor with DDQ as an acceptor: Spectroscopic studies in solution state and theoretical calculations

Ghaferah H. Al-Hazmi et al.

Summary: The charge-transfer phenomenon is of great significance in industrial processing, technological development, and clinical pharmacology. In this study, the CT complex formed by the reaction between tin(II) 2,3naphtalocyanine molecule and 2,3-dichloro-5,6-dicyano-p-benzoquinone was characterized through experimental and theoretical analysis.

JOURNAL OF MOLECULAR LIQUIDS (2022)

添加到收藏夹

Article Multidisciplinary Sciences

Analysis of the Structures, Electronic, and Spectroscopic Properties of Piperidine-Based Analgesic Drugs Carfentanil and Acetylfentanyl

Yunusa Umar

Summary: The research computed the molecular structures and electronic data of analgesic drugs carfentanil and acetylfentanyl using quantum chemical code. The results suggest that their piperidine rings have similar geometric parameters, indicating it may be a key structural feature for their analgesic activities. Additionally, introducing a carbomethoxy group into the piperidine ring of these molecules showed minimal effects on their electronic properties.

ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING (2022)

添加到收藏夹

Review Engineering, Environmental

Charge transfer complexes: Emerging and promising colorimetric real-time chemosensors for hazardous materials

Sonam Shakya et al.

Summary: CT complexes have been widely explored for their photocatalytic activities and as chemosensors for real-time detection of hazardous materials. Recent research has focused on the application of CT complexes in detecting dangerous substances in aqueous medium. Ongoing studies continue to drive advancements in this field.

JOURNAL OF HAZARDOUS MATERIALS (2021)

添加到收藏夹

Article Environmental Sciences

Development and Validation of Green UV Derivative Spectrophotometric Methods for Simultaneous Determination Metformin and Remogliflozin from Formulation: Evaluation of Greenness

Mahesh Attimarad et al.

Summary: The recent trend in green analytical chemistry focuses on the development of environmentally friendly methods using green solvents, with three ecofriendly manipulated UV spectroscopic techniques validated for the quantification of REM and MET tablets. The methods showed good linearity, sensitivity, accuracy, and precision, and were found to be suitable for regular quality control of REM and MET formulation in laboratory prepared mixtures and tablets. The proposed approaches were simple, accurate, sensitive, economic, environmentally friendly, and evaluated as eco-friendly.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2021)

添加到收藏夹

Article Education, Scientific Disciplines

Smart UV Derivative Spectrophotometric Methods for Simultaneous Determination of Metformin and Remogliflozin: Development, Validation and Application to the Formulation

Mahesh Attimarad et al.

Summary: The newly approved combination of metformin (MET) and remogliflozin (REM) for diabetes treatment underwent quality control using three simple, accurate, and reproducible spectroscopic techniques. These methods were found to be suitable for regular analysis of the formulation.

INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

Stability indicating thin-layer chromatographic method for estimation of antidiabetic drug Remogliflozin etabonate

Dimal A. Shah et al.

Summary: A sensitive and stability-indicating HPTLC method was developed for the analysis of Remogliflozin etabonate in tablets, showing high linearity, accuracy, and precision. Possible degradation pathways were determined through forced degradation studies, demonstrating the susceptibility of the drug to acid, base hydrolysis, and oxidative stress degradation. The method was successfully applied for routine quality control analysis and stability sample analysis.

FUTURE JOURNAL OF PHARMACEUTICAL SCIENCES (2021)

添加到收藏夹

Review Endocrinology & Metabolism

Remogliflozin: the new low cost SGLT-2 inhibitor for type 2 diabetes mellitus

Shubham Atal et al.

Summary: SGLT-2 inhibitors have emerged as an important class of oral drugs for treating type 2 diabetes mellitus, particularly in patients with cardiovascular or renal impairment. Despite being costly, affordability is a major consideration in developing countries like India.

DIABETOLOGY INTERNATIONAL (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Theoretical investigation of the molecular structure, vibrational spectra, and molecular docking of tramadol using density functional theory

Yunusa Umar et al.

JOURNAL OF THE CHINESE CHEMICAL SOCIETY (2020)

添加到收藏夹

Article Chemistry, Physical

Charge transfer complex based real-time colorimetric chemosensor for rapid recognition of dinitrobenzene and discriminative detection of Fe2+ ions in aqueous media and human hemoglobin

Sonam Shakya et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY (2020)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

SGLT2i: beyond the glucose-lowering effect

Lihua Ni et al.

CARDIOVASCULAR DIABETOLOGY (2020)

添加到收藏夹

Review Immunology

The Effects of Type 2 Diabetes Mellitus on Organ Metabolism and the Immune System

Gholamreza Daryabor et al.

FRONTIERS IN IMMUNOLOGY (2020)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Postprandial Glucose Spikes, an Important Contributor to Cardiovascular Disease in Diabetes?

Nordin M. J. Hanssen et al.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2020)

添加到收藏夹

Article Chemistry, Analytical

Stability indicating liquid chromatographic method for the estimation of remogliflozin etabonate

Dimal A. Shah et al.

JOURNAL OF CHEMICAL METROLOGY (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Theoretical studies of the rotational and tautomeric states, electronic and spectroscopic properties of favipiravir and its structural analogues: a potential drug for the treatment of COVID-19

Yunusa Umar

JOURNAL OF TAIBAH UNIVERSITY FOR SCIENCE (2020)

添加到收藏夹

Article Chemistry, Analytical

Development and Validation of Rapid RP-HPLC and Green Second-Derivative UV Spectroscopic Methods for Simultaneous Quantification of Metformin and Remogliflozin in Formulation Using Experimental Design

Mahesh Attimarad et al.

SEPARATIONS (2020)

添加到收藏夹

Article Pharmacology & Pharmacy

Emerging Role of SGLT-2 Inhibitors for the Treatment of Obesity

Maria J. Pereira et al.

DRUGS (2019)

添加到收藏夹

Article Chemistry, Inorganic & Nuclear

Conformational Stabilities, Rotational Barriers, and Vibrational Spectra of 2-Pyrrolecarboxaldehyde and 3-Pyrrolecarboxaldehyde Calculated Using Density Functional Theory

Y. Umar et al.

JOURNAL OF STRUCTURAL CHEMISTRY (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Exploring Colorimetric Real-Time Sensing Behavior of a Newly Designed CT Complex toward Nitrobenzene and Co2+: Spectrophotometric, DFT/TD-DFT, and Mechanistic Insights

Ishaat M. Khan et al.

ACS OMEGA (2019)

添加到收藏夹

Article Chemistry, Physical

DFT Study of the Molecular Structure, Conformational Preference, HOMO, LUMO, and Vibrational Analysis of 2-, and 3-Furoyl Chloride

Yunusa Umar et al.

JOURNAL OF SOLUTION CHEMISTRY (2017)

添加到收藏夹

Review Chemistry, Multidisciplinary

Analytical techniques in pharmaceutical analysis: A review

Masoom Raza Siddiqui et al.

ARABIAN JOURNAL OF CHEMISTRY (2017)

添加到收藏夹

Review Chemistry, Analytical

Metrics for green analytical chemistry

Marek Tobiszewski

ANALYTICAL METHODS (2016)

添加到收藏夹

Article Chemistry, Physical

Internal Rotation of 2-, 3-and 4-Pyridine Carboxaldehydes and Their Chalcogen Analogues (S and Se) in the Gas and Solution Phases: A Theoretical Investigation

Hassan H. Abdallah et al.

JOURNAL OF SOLUTION CHEMISTRY (2016)

添加到收藏夹

Article Chemistry, Inorganic & Nuclear

DENSITY FUNCTIONAL THEORY STUDIES OF CONFORMATIONAL STABILITIES AND ROTATIONAL BARRIERS OF 2-AND 3-THIOPHENECARBOXALDEHYDES

Y. Umar et al.

JOURNAL OF STRUCTURAL CHEMISTRY (2016)

添加到收藏夹

Article Chemistry, Physical

Conformational and Vibrational Analysis of 2-, 3-and 4-Pyridinecarbonyl Chloride Using DFT

Sahar Abdalla et al.

ZEITSCHRIFT FUR PHYSIKALISCHE CHEMIE-INTERNATIONAL JOURNAL OF RESEARCH IN PHYSICAL CHEMISTRY & CHEMICAL PHYSICS (2016)

添加到收藏夹

Review Chemistry, Analytical

The 12 principles of green analytical chemistry and the SIGNIFICANCE mnemonic of green analytical practices

Agnieszka Galuszka et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2013)

添加到收藏夹

Article Pharmacology & Pharmacy

First human dose-escalation study with remogliflozin etabonate, a selective inhibitor of the sodium-glucose transporter 2 (SGLT2), in healthy subjects and in subjects with type 2 diabetes mellitus

Anita Kapur et al.

BMC PHARMACOLOGY & TOXICOLOGY (2013)

添加到收藏夹

Article Pharmacology & Pharmacy

Safety, pharmacokinetics and pharmacodynamics of remogliflozin etabonate, a novel SGLT2 inhibitor, and metformin when co-administered in subjects with type 2 diabetes mellitus

Elizabeth K. Hussey et al.

BMC PHARMACOLOGY & TOXICOLOGY (2013)

添加到收藏夹

Article Chemistry, Analytical

Analytical Eco-Scale for assessing the greenness of analytical procedures

Agnieszka Galuszka et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2012)

添加到收藏夹

Article Chemistry, Analytical

Green Analytical Chemistry

S. Armenta et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2008)

添加到收藏夹

Article Spectroscopy

Ab initio and DFT studies of the molecular structures and vibrational spectra of succinonitrile

Yunusa Umar et al.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2007)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.