期刊
NATURE MEDICINE
卷 22, 期 11, 页码 1207-1208出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nm.4227
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资金
- NINDS NIH HHS [R01 NS081333] Funding Source: Medline
Misfolded and hyperphosphorylated forms of the microtubule-associated protein tau are thought to be responsible for some degree of neurodegeneration. The demonstration of a novel toxic cleavage of tau by caspase-2 opens up new therapeutic avenues.
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