期刊
NATURE IMMUNOLOGY
卷 17, 期 1, 页码 2-8出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/ni.3341
关键词
-
类别
资金
- National Cancer Institute of the US National Institutes of Health [P30CA008748]
- Wellcome Trust [WT101853MA]
- European Research Council [2010-StG-261299]
- Institut Pasteur
- Agence Nationale de la Recherche (Laboratoire d'Excellence Revive, Investissement d'Avenir) [ANR-10-LABX-73]
- NATIONAL CANCER INSTITUTE [P30CA008748] Funding Source: NIH RePORTER
The molecular and cellular mechanisms that underlie the many roles of macrophages in health and disease states in vivo remain poorly understood. The purpose of this Review is to present and discuss current knowledge on the developmental biology of macrophages, as it underlies the concept of a layered myeloid system composed of 'resident' macrophages that originate mainly from progenitor cells generated in the yolk sac and of 'passenger' or 'transitory' myeloid cells that originate and renew from bone marrow hematopoietic stem cells, and to provide a framework for investigating the functions of macrophages in vivo.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据