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Article
Biochemistry & Molecular Biology
Pengcheng Tu et al.
Summary: Mounting evidence has shown that berries have various health benefits. This study demonstrated that the administration of black raspberries can change the gut microbiota and its functional metabolites, resulting in a reduction of arsenic-induced toxicity. These findings suggest that the interactions between black raspberries and arsenic exposure occur through the gut microbiota, and modulating the gut microbiota and its metabolites could contribute to the protective effects of black raspberries against arsenic toxicity.
Article
Biochemistry & Molecular Biology
Pengcheng Tu et al.
Summary: Dietary modulation of gut microbiota has gained attention recently. Previous studies have shown that black raspberry can effectively modulate the gut microbiota. This follow-up study focused on characterizing the functional metabolites profile in the gut microbiome modulated by anthocyanins. Results demonstrated that an anthocyanin called cyanidin-3-glucoside significantly changed the gut microbiota composition and metabolic profile in mice. The study suggests the involvement of gut microbiota in the health benefits of anthocyanin consumption.
Article
Biochemistry & Molecular Biology
Yanwei Li et al.
Summary: The study demonstrated that lithocholic acid (LCA) alleviated toxic apoptosis caused by Deoxynivalenol (DON) by regulating cholesterol metabolism and modulating the expression of key genes involved in cholesterol biosynthesis and transformation in DON-exposed cells.
Article
Biochemistry & Molecular Biology
Olha Kostiuchenko et al.
Summary: Cysteine proteases from pineapple and papaya have beneficial effects on human health by modulating gut microbiota and enhancing protein digestion capacity. In this study, bromelain and papain supplementation in mice increased the abundance of Akkermansia muciniphila and improved pancreatic trypsin. However, high doses of the enzymes disrupted epithelial integrity and increased paracellular permeability.
Article
Biochemistry & Molecular Biology
Chwan-Li Shen et al.
Summary: Natural bioactive compounds, such as geranylgeraniol and green tea polyphenols, were found to alleviate muscle atrophy and modify gut microbiome composition in mice fed a high-fat diet. The combination of geranylgeraniol and green tea polyphenols resulted in decreased body and fat mass, increased skeletal muscle mass, and changes in gut microbiota composition.
