☆ 4.7 Review

Inhibitors of NLRP3 Inflammasome in Ischemic Heart Disease: Focus on Functional and Redox Aspects

ANTIOXIDANTS (2023)

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Summary: The study aimed to investigate the effects of the selective NLRP3 inflammasome inhibitor MCC950 on post-resuscitation myocardial function and survival. Results showed that MCC950 improved post-resuscitation myocardial function and microcirculation, reduced inflammatory response, and increased survival and neurologic deficit scores.

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