Weak Radiofrequency Field Effects on Chemical Parameters That Characterize Oxidative Stress in Human Fibrosarcoma and Fibroblast Cells

In the last few decades, evidence has surfaced that weak radiofrequency (RF) fields can influence biological systems. This work aims to improve our understanding of how externally applied weak RF fields alter concentrations of chemical parameters that characterize oxidative stress. We conducted a series of experiments to investigate the effects of applying weak RF magnetic fields within the 3-5 MHz region on mitochondrial respiration in both human fibrosarcoma and fibroblast cells over a period of four days. Our experimental data show that RF fields between 3 and 5 MHz were able to change the modulation of mitochondrial signaling by changing the cell growth, mitochondrial mass, and oxidative stress. Exposure to RF fields at 4.2 MHz significantly increased the mitochondrial mass and oxidative stress in fibrosarcoma cells. There are substantial concerns that extended exposure to weak RF fields can lead to health effects. The ability to control these parameters by external magnetic fields may have important clinical implications.

Automated summary

In recent decades, evidence has shown that weak radiofrequency (RF) fields can have an impact on biological systems. This study aimed to enhance our understanding of how externally applied weak RF fields influence concentrations of chemical parameters associated with oxidative stress. Through a series of experiments, we investigated the effects of weak RF magnetic fields between 3 and 5 MHz on mitochondrial respiration in human fibrosarcoma and fibroblast cells over a four-day period. The results demonstrated that RF fields within this frequency range could modulate mitochondrial signaling by altering cell growth, mitochondrial mass, and oxidative stress. Exposure to RF fields at 4.2 MHz significantly increased mitochondrial mass and oxidative stress in fibrosarcoma cells. There are significant concerns regarding the potential health effects of prolonged exposure to weak RF fields. The ability to control these parameters through external magnetic fields may carry important clinical implications.