☆ 4.5 Review

Association of preserved ratio impaired spirometry with mortality: a systematic review and meta-analysis

EUROPEAN RESPIRATORY REVIEW (2023)

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Impaired Spirometry and COPD Increase the Risk of Cardiovascular Disease: A Canadian Cohort Study

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Preserved Ratio Impaired Spirometry in Relationship to Cardiovascular Outcomes A Large Prospective Cohort Study

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Summary: Preserved ratio impaired spirometry (PRISm) findings are associated with an increased risk of cardiovascular events, but transitioning from PRISm to normal lung function can reduce this risk.

CHEST (2023)

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Assessment of Preserved Ratio Impaired Spirometry Using Pre- and Post-Bronchodilator Spirometry in a Randomly Sampled Symptomatic Cohort

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Risks of Mortality and Airflow Limitation in Japanese Individuals with Preserved Ratio Impaired Spirometry

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Summary: The study found that preserved ratio impaired spirometry (PRISm) was associated with increased risks of death and incident airflow limitation (AFL) in a Japanese population.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2022)

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AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2022)

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Significant Spirometric Transitions and Preserved Ratio Impaired Spirometry Among Ever Smokers

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Summary: The study found that individuals with preserved ratio impaired spirometry (PRISm) often experience transitions in lung function, which are associated with both obstructive and normal spirometry.

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Prevalence and risk factors for COPD in subjects with preserved ratio impaired spirometry

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Summary: Preserved ratio impaired spirometry (PRISm) is a subtype of chronic obstructive pulmonary disease (COPD) and is associated with the progression of COPD. This study, based on medical check-up data, found that the prevalence of PRISm was 10% but increased to 23.6% at the best cut-off for predicting the progression of COPD.

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Association Between Preserved Ratio Impaired Spirometry and Clinical Outcomes in US Adults

Emily S. Wan et al.

Summary: In a large cohort study of US adults, PRISm was associated with increased risk of mortality, adverse cardiovascular and respiratory outcomes, with obesity, female sex, and smoking being significant risk factors. Further research is needed to determine causality.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

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Prevalence, risk factors, and clinical implications of preserved ratio impaired spirometry: a UK Biobank cohort analysis

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Lancet Respiratory Medicine (2021)

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The PRISMA 2020 statement: an updated guideline for reporting systematic reviews

Matthew J. Page et al.

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BMJ-BRITISH MEDICAL JOURNAL (2021)

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Trajectory of Preserved Ratio Impaired Spirometry: Natural History and Long-Term Prognosis

Jacob Louis Marott et al.

Summary: The study investigated the natural history and long-term prognosis of different PRISm trajectories, finding that individuals with persistent PRISm trajectory are at increased risk of cardiopulmonary disease and mortality, while those who recover to normal from PRISm do not have increased risk.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2021)

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Trajectory and mortality of preserved ratio impaired spirometry: the Rotterdam Study

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Epidemiology, genetics, and subtyping of preserved ratio impaired spirometry (PRISm) in COPDGene

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