☆ 4.7 Article

Chitosan nanoparticles for sustained release of metformin and its derived synthetic biopolymer for bone regeneration

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Biochemistry & Molecular Biology

Cytocompatible drug delivery hydrogels based on carboxymethylagarose/chitosan pH-responsive polyelectrolyte complexes

J. Andres Ortiz et al.

Summary: In this study, pH-responsive CMA/CS hydrogels were prepared and the model drug DS was successfully loaded into the PCE. The results showed that the hydrogels had high loading capacity and release efficiency. Cell viability assay demonstrated the non-toxic nature of the hydrogels. Therefore, CMA/CS PECs can be applied for dermal drug delivery.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022)

添加到收藏夹

Article Engineering, Biomedical

Constructions of ROS-responsive titanium-hydroxyapatite implant for mesenchymal stem cell recruitment in peri-implant space and bone formation in osteoporosis microenvironment

Maohua Chen et al.

Summary: By fabricating a ROS-responsive system on titanium surface, MSC recruitment and osteogenic differentiation can be enhanced, providing a potential treatment for osteoporotic fractures.

BIOACTIVE MATERIALS (2022)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

Maxillary sinus floor augmentation comparing bovine versus porcine bone xenografts mixed with autogenous bone graft. A split-mouth randomized controlled trial

Pablo Galindo-Moreno et al.

Summary: This study compared the effectiveness of two xenografts for maxillary sinus floor augmentation. The results showed that anorganic bovine bone and porcine bone mineral combined with maxillary autogenous cortical bone had similar biological and radiological features.

CLINICAL ORAL IMPLANTS RESEARCH (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Chitosan Hydrogel Supplemented with Metformin Promotes Neuron-like Cell Differentiation of Gingival Mesenchymal Stem Cells

Shanglin Cai et al.

Summary: This study investigated the potential of metformin as an enhancer on neuronal differentiation of GMSCs in the growth environment of chitosan hydrogel. Results showed that metformin could promote the differentiation of GMSCs into neuron-like cells with enhanced expression of neuro-related markers.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

添加到收藏夹

Article Biotechnology & Applied Microbiology

α-Hemihydrate calcium sulfate/n-hydroxyapatite combined with metformin promotes osteogenesis in vitro and in vivo

Sirui Liu et al.

Summary: This study investigated the effects of different concentrations of metformin on an alpha-CSH/nHA composite, and found that metformin loading enhanced the osteogenic ability of the composite. The composite material loaded with 500μM metformin showed the strongest osteoinduction ability in a rat cranial defect model.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2022)

添加到收藏夹

Review Biochemistry & Molecular Biology

Advances in Growth Factor Delivery for Bone Tissue Engineering

Erica Resende Oliveira et al.

Summary: Tissue engineering and regenerative medicine have addressed some shortcomings in the treatment of bone diseases, particularly in simulating the extracellular matrix and guiding bone repair. Combining scaffolding and growth factors shows great potential in promoting the effectiveness of bone regeneration methods.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Co-delivery of bufalin and nintedanib via albumin sub-microspheres for synergistic cancer therapy

Ying Xu et al.

Summary: Albumin sub-microspheres developed using coaxial-electrospray technology for co-delivery of bufalin and nintedanib show superior tumor targeting efficiency and synergistic therapeutic effect. This provides a novel method for fabricating an albumin-based drug delivery system and a potential efficient combination therapeutic strategy for tumor treatment.

JOURNAL OF CONTROLLED RELEASE (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Biomaterial Properties Modulating Bone Regeneration

Yi Zhu et al.

Summary: Biomaterial scaffolds have gained attention for their potential in tissue engineering, supporting cell attachment and influencing cell behavior for tissue repair. They can also act as delivery vehicles to modulate regeneration processes. As potential bone graft substitutes, the physicochemical properties of biomaterial scaffolds play a key role in influencing cell behavior and outcomes in bone regeneration.

MACROMOLECULAR BIOSCIENCE (2021)

添加到收藏夹

Article Cell & Tissue Engineering

Pharmacological Approaches and Regeneration of Bone Defects with Dental Pulp Stem Cells

M. Adamička et al.

Stem Cells International (2021)

添加到收藏夹

Review Dentistry, Oral Surgery & Medicine

Biomaterial-based strategies for maxillofacial tumour therapy and bone defect regeneration

Bowen Tan et al.

Summary: Maxillofacial tumours not only involve dealing with the tumours themselves, but also repairing jaw bone defects. Utilizing biomaterials can enhance tumour treatment efficiency, reduce recurrence and metastasis, and provide new promising anti-tumour therapies for patients.

INTERNATIONAL JOURNAL OF ORAL SCIENCE (2021)

添加到收藏夹

Article Engineering, Biomedical

Metformin Carbon Dots for Promoting Periodontal Bone Regeneration via Activation of ERK/AMPK Pathway

Chunxia Ren et al.

Summary: Metformin carbon dots (MCDs) prepared in this study showed excellent biocompatibility and enhanced osteogenic activity more effectively under inflammatory conditions compared to metformin. MCDs also demonstrated promising potential for regenerating lost alveolar bone in periodontitis rat model, indicating a novel nanomaterial for periodontitis treatment with potential pharmacological targets.

ADVANCED HEALTHCARE MATERIALS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Oral delivery of metformin by chitosan nanoparticles for polycystic kidney disease

Jonathan Wang et al.

Summary: Nanoparticles synthesized from chitosan showed promising mucoadhesive and permeation capabilities in vitro, with improved controlled release and serum delivery over 24 hours. Loading metformin into chitosan nanoparticles resulted in lower cyst burden in a PKD murine model, demonstrating good tolerance and kidney health. This study presents a novel, oral nanoformulation for chronic diseases like PKD, building upon previous chitosan-based drug delivery approaches.

JOURNAL OF CONTROLLED RELEASE (2021)

添加到收藏夹

Editorial Material Endocrinology & Metabolism

Bacteria transmit metformin-associated lifespan extension

Lesley T. MacNeil et al.

NATURE REVIEWS ENDOCRINOLOGY (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Biodistribution and pharmacokinetics of thiolated chitosan nanoparticles for oral delivery of insulin in vivo

Sekar Sudhakar et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

添加到收藏夹

Review Endocrinology & Metabolism

Metformin and Its Benefits for Various Diseases

Ziquan Lv et al.

FRONTIERS IN ENDOCRINOLOGY (2020)

添加到收藏夹

Review Chemistry, Multidisciplinary

Agarose-based biomaterials for advanced drug delivery

Mohsen Khodadadi Yazdi et al.

JOURNAL OF CONTROLLED RELEASE (2020)

添加到收藏夹

Review Chemistry, Multidisciplinary

Chitosan hydrogels for sustained drug delivery

S. Peers et al.

JOURNAL OF CONTROLLED RELEASE (2020)

添加到收藏夹

Article Cell & Tissue Engineering

Metformin enhances osteogenic differentiation of stem cells from human exfoliated deciduous teeth through AMPK pathway

Xuedan Zhao et al.

JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

Chitosan biomaterials application in dentistry

Elaheh Fakhri et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

添加到收藏夹

Article Engineering, Biomedical

Novel, cost-effective, Cu-doped calcium silicate nanoparticles for bone fracture intervention: Inherent bioactivity and in vivo performance

Mostafa Mabrouk et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

Combined synergetic potential of metformin loaded pectin-chitosan biohybrids nanoparticle for NIDDM

Santhosh Kumar Chinnaiyan et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

添加到收藏夹

Review Biochemistry & Molecular Biology

Application of Chitosan in Bone and Dental Engineering

Alicia Aguilar et al.

MOLECULES (2019)

添加到收藏夹

Article Nanoscience & Nanotechnology

Triple PLGA/PCL Scaffold Modification Including Silver Impregnation, Collagen Coating, and Electrospinning Significantly Improve Biocompatibility, Antimicrobial, and Osteogenic Properties for Orofacial Tissue Regeneration

Yunzhu Qian et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

添加到收藏夹

Review Medicine, Research & Experimental

Metformin; an old antidiabetic drug with new potentials in bone disorders

Saman Bahrambeigi et al.

BIOMEDICINE & PHARMACOTHERAPY (2019)

添加到收藏夹

Review Cell Biology

The roles of signaling pathways in bone repair and regeneration

Maryam Majidinia et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2018)

添加到收藏夹

Article Pharmacology & Pharmacy

Metformin-Loaded Hyaluronic Acid Nanostructure for Oral Delivery

Sonal Bhujbal et al.

AAPS PHARMSCITECH (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Smart Human-Serum-Albumin-As2O3 Nanodrug with Self-Amplified Folate Receptor-Targeting Ability for Chronic Myeloid Leukemia Treatment

Yongbo Peng et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

添加到收藏夹

Article Biochemical Research Methods

Simultaneous Determination of Metformin, Metoprolol and its Metabolites in Rat Plasma by LC-MS-MS: Application to Pharmacokinetic Interaction Study

Yan-rong Ma et al.

JOURNAL OF CHROMATOGRAPHIC SCIENCE (2016)

添加到收藏夹

Review Engineering, Biomedical

Biofabrication of bone tissue: approaches, challenges and translation for bone regeneration

Daniel Tang et al.

BIOMATERIALS (2016)

添加到收藏夹

Article Biochemistry & Molecular Biology

Insulin receptor substrate-1 time-dependently regulates bone formation by controlling collagen Iα2 expression via miR-342

Yue Guo et al.

FASEB JOURNAL (2016)

添加到收藏夹

Article Nanoscience & Nanotechnology

Bioactive silica nanoparticles reverse age-associated bone loss in mice

M. Neale Weitzmann et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2015)

添加到收藏夹

Article Engineering, Biomedical

Biocompatible polymer coating of titania nanotube arrays for improved drug elution and osteoblast adhesion

Karan Gulati et al.

ACTA BIOMATERIALIA (2012)

添加到收藏夹

Article Surgery

Bone Biology and Physiology: Part I. The Fundamentals

Donald W. Buck et al.

PLASTIC AND RECONSTRUCTIVE SURGERY (2012)

添加到收藏夹

Review Medicine, General & Internal

Bone regeneration: current concepts and future directions

Rozalia Dimitriou et al.

BMC MEDICINE (2011)

添加到收藏夹

Article Immunology

Chitosan oligosaccharides protect mice from LPS challenge by attenuation of inflammation and oxidative stress

Ying Qiao et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2011)

添加到收藏夹

Article Chemistry, Medicinal

Chitooligosaccharides suppress the level of protein expression and acetylcholinesterase activity induced by Aβ25-35 in PC12 cells

Sang-Hoon Lee et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)

添加到收藏夹

Article Nanoscience & Nanotechnology

Chitosan and lactic acid-grafted chitosan nanoparticles as carriers for prolonged drug delivery

Narayan Bhattarai et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2006)

添加到收藏夹

Article Orthopedics

The biology of bone grafting

SN Khan et al.

JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS (2005)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.