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Regulations of Glycolytic Activities on Macrophages Functions in Tumor and Infectious Inflammation
Qing Yu et al.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2020)
The Mincle/Syk/NF-κB Signaling Circuit Is Essential for Maintaining the Protumoral Activities of Tumor-Associated Macrophages
Chunjie Li et al.
CANCER IMMUNOLOGY RESEARCH (2020)
Thrombospondin-1 promotes haemostasis through modulation of cAMP signalling in blood platelets.
Ahmed Aburima et al.
BLOOD (2020)
Neural transcription factor Pou4f1 promotes renal fibrosis via macrophage-myofibroblast transition
Patrick Ming-Kuen Tang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Basement membrane damage by ROS- and JNK-mediated Mmp2 activation drives macrophage recruitment to overgrown tissue
Neha Diwanji et al.
NATURE COMMUNICATIONS (2020)
STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression
Jesse J. Balic et al.
NATURE COMMUNICATIONS (2020)
FGF2 alters macrophage polarization, tumour immunity and growth and can be targeted during radiotherapy
Jae Hong Im et al.
NATURE COMMUNICATIONS (2020)
Disabled Homolog 2 Controls Prometastatic Activity of Tumor- Associated Macrophages
Ilaria Marigo et al.
CANCER DISCOVERY (2020)
Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis
Dominik Trzupek et al.
GENOME MEDICINE (2020)
Targeting tumor-associated macrophages and granulocytic myeloid-derived suppressor cells augments PD-1 blockade in cholangiocarcinoma
Emilien Loeuillard et al.
JOURNAL OF CLINICAL INVESTIGATION (2020)
Cancer stem cell secretome in the tumor microenvironment: a key point for an effective personalized cancer treatment
Julia Lopez de Andres et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2020)
Concepts of extracellular matrix remodelling in tumour progression and metastasis
Juliane Winkler et al.
NATURE COMMUNICATIONS (2020)
Endometrial Cancer Cells Promote M2-Like Macrophage Polarization by Delivering Exosomal miRNA-21 under Hypoxia Condition
Li Xiao et al.
JOURNAL OF IMMUNOLOGY RESEARCH (2020)
CD47/SIRP alpha blocking peptide identification and synergistic effect with irradiation for cancer immunotherapy
Hongfei Wang et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2020)
Therapy Resistance, Cancer Stem Cells and ECM in Cancer: The Matrix Reloaded
Kousik Kesh et al.
CANCERS (2020)
Tumor-derived exosomal miR-934 induces macrophage M2 polarization to promote liver metastasis of colorectal cancer
Senlin Zhao et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2020)
Tumor-associated macrophage, angiogenesis and lymphangiogenesis markers predict prognosis of non-small cell lung cancer patients
Ilseon Hwang et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2020)
TLR signaling adapter BCAP regulates inflammatory to reparatory macrophage transition by promoting histone lactylation
Ricardo A. Irizarry-Caro et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Inhibition of the CCL2 receptor, CCR2, enhances tumor response to immune checkpoint therapy
Megan M. Tu et al.
COMMUNICATIONS BIOLOGY (2020)
Macrophage-Derived Vascular Endothelial Growth Factor-A Is Integral to Neuromuscular Junction Reinnervation after Nerve Injury
Chuieng-Yi Lu et al.
JOURNAL OF NEUROSCIENCE (2020)
Genetically engineered macrophages persist in solid tumors and locally deliver therapeutic proteins to activate immune responses
Katherine J. Brempelis et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2020)
Breast cancer cell debris diminishes therapeutic efficacy through heme oxygenase-1-mediated inactivation of M1-like tumor-associated macrophages
Seung Hyeon Kim et al.
NEOPLASIA (2020)
Transcriptional regulatory networks of tumor-associated macrophages that drive malignancy in mesenchymal glioblastoma
Jason K. Sa et al.
GENOME BIOLOGY (2020)
The updated landscape of tumor microenvironment and drug repurposing
Ming-Zhu Jin et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)
Tumor-initiating cells establish an IL-33-TGF-β niche signaling loop to promote cancer progression
Sachiko Taniguchi et al.
SCIENCE (2020)
IL-4 induces M2 macrophages to produce sustained analgesia via opioids
Melih O. Celik et al.
JCI INSIGHT (2020)
Targeting cancer stem cell pathways for cancer therapy
Liqun Yang et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)
Controlled M1-to-M2 transition of aged macrophages by calcium phosphate coatings
Jumana R. Alhamdi et al.
BIOMATERIALS (2019)
Tumor-Associated Macrophages Derived TGF-β-Induced Epithelial to Mesenchymal Transition in Colorectal Cancer Cells through Smad2,3-4/Snail Signaling Pathway
Jianhui Cai et al.
CANCER RESEARCH AND TREATMENT (2019)
Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets
Luca Cassetta et al.
CANCER CELL (2019)
Immunotherapeutic Blockade of Macrophage Clever-1 Reactivates the CD8+ T-cell Response against Immunosuppressive Tumors
Miro Viitala et al.
CLINICAL CANCER RESEARCH (2019)
Antigen delivery targeted to tumor-associated macrophages overcomes tumor immune resistance
Daisuke Muraoka et al.
JOURNAL OF CLINICAL INVESTIGATION (2019)
CCL22 controls immunity by promoting regulatory T cell communication with dendritic cells in lymph nodes
Moritz Rapp et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2019)
Macrophages: versatile players in renal inflammation and fibrosis
Patrick Ming-Kuen Tang et al.
NATURE REVIEWS NEPHROLOGY (2019)
IL-10 produced by macrophages regulates epithelial integrity in the small intestine
Tina L. Morhardt et al.
SCIENTIFIC REPORTS (2019)
M2 macrophages mediate sorafenib resistance by secreting HGF in a feed-forward manner in hepatocellular carcinoma
Ningning Dong et al.
BRITISH JOURNAL OF CANCER (2019)
M2-like tumor-associated macrophages-secreted EGF promotes epithelial ovarian cancer metastasis via activating EGFR-ERK signaling and suppressing lncRNA LIMT expression
Xiang-Yang Zeng et al.
CANCER BIOLOGY & THERAPY (2019)
HDAC6 Suppresses Let-7i-5p to Elicit TSP1/CD47-Mediated Anti-Tumorigenesis and Phagocytosis of Hepatocellular Carcinoma
Hee Doo Yang et al.
HEPATOLOGY (2019)
Macrophage CCL22 expression in the tumor microenvironment and implications for survival in patients with squamous cell carcinoma of the tongue
Satoshi Kimura et al.
JOURNAL OF ORAL PATHOLOGY & MEDICINE (2019)
Macrophages-Triggered Sequential Remodeling of Endothelium-Interstitial Matrix to Form Pre-Metastatic Niche in Microfluidic Tumor Microenvironment
Hyunho Kim et al.
ADVANCED SCIENCE (2019)
Tumor-associated macrophages in tumor metastasis: biological roles and clinical therapeutic applications
Yuxin Lin et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2019)
TSPAN8 promotes cancer cell stemness via activation of sonic Hedgehog signaling
Rongxuan Zhu et al.
NATURE COMMUNICATIONS (2019)
The importance of inter-individual Kupffer cell variability in the governance of hepatic toxicity in a 3D primary human liver microtissue model
Ali Kermanizadehl et al.
SCIENTIFIC REPORTS (2019)
NF-κB Signaling in Macrophages: Dynamics, Crosstalk, and Signal Integration
Michael G. Dorrington et al.
FRONTIERS IN IMMUNOLOGY (2019)
Surfactant protein-D modulation of pulmonary macrophage phenotype is controlled by S-nitrosylation
Chang-Jiang Guo et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2019)
MMP-9 secreted by tumor associated macrophages promoted gastric cancer metastasis through a PI3K/AKT/Snail pathway
Lin Liu et al.
BIOMEDICINE & PHARMACOTHERAPY (2019)
Specific targeting of CD163+ TAMs mobilizes inflammatory monocytes and promotes T cell-mediated tumor regression
Anders Etzerodt et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2019)
Hepatocyte Growth Factor Regulates Macrophage Transition to the M2 Phenotype and Promotes Murine Skeletal Muscle Regeneration
Wooshik Choi et al.
FRONTIERS IN PHYSIOLOGY (2019)
Exosome-Guided Phenotypic Switch of M1 to M2 Macrophages for Cutaneous Wound Healing
Hyosuk Kim et al.
ADVANCED SCIENCE (2019)
Histone deacetylase inhibition promotes intratumoral CD8+ T-cell responses, sensitizing murine breast tumors to anti-PD1
Tyler R. McCaw et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2019)
Immune cell PD-L1 co-localizes with macrophages and is associated with outcome in PD-1 pathway blockade therapy
Yuting Liu et al.
CLINICAL CANCER RESEARCH (2019)
Suppressing miR-21 activity in tumor-associated macrophages promotes an antitumor immune response
Mahnaz Sahraei et al.
JOURNAL OF CLINICAL INVESTIGATION (2019)
PD-L1 expression on tumor-infiltrating immune cells is highly associated with M2 TAM and aggressive malignant potential in patients with resected non-small cell lung cancer
Ryota Sumitomo et al.
LUNG CANCER (2019)
VISTA is an acidic pH-selective ligand for PSGL-1
Robert J. Johnston et al.
NATURE (2019)
Genetic programming of macrophages to perform anti-tumor functions using targeted mRNA nanocarriers
F. Zhang et al.
NATURE COMMUNICATIONS (2019)
Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling
Rachel Eyre et al.
NATURE COMMUNICATIONS (2019)
mTORC1-mediated polarization of M1 macrophages and their accumulation in the liver correlate with immunopathology in fatal ehrlichiosis
Mohamed Haloul et al.
SCIENTIFIC REPORTS (2019)
CD206+ tumor-associated macrophages promote proliferation and invasion in oral squamous cell carcinoma via EGF production
A. S. M. Rafiul Haque et al.
SCIENTIFIC REPORTS (2019)
Insufficient production of IL-10 from M2 macrophages impairs in vitro endothelial progenitor cell differentiation in patients with Moyamoya disease
Eiichiro Nagata et al.
SCIENTIFIC REPORTS (2019)
Impairment of NKG2D-Mediated Tumor Immunity by TGF-β
Mariya Lazarova et al.
FRONTIERS IN IMMUNOLOGY (2019)
TGFβ induces sternness through non-canonical AKT-FOXO3a axis in oral squamous cell carcinoma
Kan Li et al.
EBIOMEDICINE (2019)
Tumor-Associated Macrophages Enhance Tumor Hypoxia and Aerobic Glycolysis
Hoibin Jeong et al.
CANCER RESEARCH (2019)
NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice
Shuang Liang et al.
GASTROENTEROLOGY (2019)
Autocrine VEGF signalling on M2 macrophages regulates PD-L1 expression for immunomodulation of T cells
Yin-Siew Lai et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2019)
Turning foes to friends: targeting cancer-associated fibroblasts
Xueman Chen et al.
NATURE REVIEWS DRUG DISCOVERY (2019)
New insights into the mechanisms of epithelial-mesenchymal transition and implications for cancer
Anushka Dongre et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
Blocking IL-1β reverses the immunosuppression in mouse breast cancer and synergizes with anti-PD-1 for tumor abrogation
Irena Kaplanov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
M2 macrophages and regulatory T cells in lethal prostate cancer
Ann Erlandsson et al.
PROSTATE (2019)
CCL18 secreted from M2 macrophages promotes migration and invasion via the PI3K/Akt pathway in gallbladder cancer
Zhenyu Zhou et al.
CELLULAR ONCOLOGY (2019)
Gastric cancer-derived mesenchymal stromal cells trigger M2 macrophage polarization that promotes metastasis and EMT in gastric cancer
Wei Li et al.
CELL DEATH & DISEASE (2019)
Elevated Levels of TNF-α and Decreased Levels of CD68-Positive Macrophages in Primary Tumor Tissues Are Unfavorable for the Survival of Patients With Nasopharyngeal Carcinoma
Yahui Yu et al.
TECHNOLOGY IN CANCER RESEARCH & TREATMENT (2019)
CD137 promotes bone metastasis of breast cancer by enhancing the migration and osteoclast differentiation of monocytes/macrophages
Pengling Jiang et al.
THERANOSTICS (2019)
Human M2 Macrophages Limit NK Cell Effector Functions through Secretion of TGF-β and Engagement of CD85j
Sol Y. Nunez et al.
JOURNAL OF IMMUNOLOGY (2018)
Blocking the CD47-SIRP alpha axis by delivery of anti-CD47 antibody induces antitumor effects in glioma and glioma stem cells
Feng Li et al.
ONCOIMMUNOLOGY (2018)
Co-culture of ovarian cancer stem-like cells with macrophages induced SKOV3 cells stemness via IL-8/STAT3 signaling
Yingxia Ning et al.
BIOMEDICINE & PHARMACOTHERAPY (2018)
TGF-β Mediates Renal Fibrosis via the Smad3-Erbb4-IR Long Noncoding RNA Axis
Min Feng et al.
MOLECULAR THERAPY (2018)
M2-polarized tumor-associated macrophages facilitated migration and epithelial-mesenchymal transition of HCC cells via the TLR4/STAT3 signaling pathway
Rong-Rong Yao et al.
WORLD JOURNAL OF SURGICAL ONCOLOGY (2018)
Defining the role of the tumor vasculature in antitumor immunity and immunotherapy
Marco B. Schaaf et al.
CELL DEATH & DISEASE (2018)
Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation
Mana Taki et al.
NATURE COMMUNICATIONS (2018)
IL-23 and IL-1β Drive Human Th17 Cell Differentiation and Metabolic Reprogramming in Absence of CD28 Costimulation
Shankar Revu et al.
CELL REPORTS (2018)
IL-23-induced macrophage polarization and its pathological roles in mice with imiquimod-induced psoriasis
Yuzhu Hou et al.
PROTEIN & CELL (2018)
mir-466a Targeting of TgF-β2 contributes to FoxP3+ regulatory T cell Differentiation in a Murine Model of allogeneic Transplantation
William Becker et al.
FRONTIERS IN IMMUNOLOGY (2018)
TLR-3 Stimulation Skews M2 Macrophages to M1 Through IFN-αβ Signaling and Restricts Tumor Progression
Aurobind Vidyarthi et al.
FRONTIERS IN IMMUNOLOGY (2018)
Macrophages sensing oxidized DAMPs reprogram their metabolism to support redox homeostasis and inflammation through a TLR2-Syk-ceramide dependent mechanism
Vlad Serbulea et al.
MOLECULAR METABOLISM (2018)
Tumor-associated macrophages derived CCL18 promotes metastasis in squamous cell carcinoma of the head and neck
Li She et al.
CANCER CELL INTERNATIONAL (2018)
Macrophage angiotensin II type 2 receptor triggers neuropathic pain
Andrew J. Shepherd et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
CD69 enhances immunosuppressive function of regulatory T-cells and attenuates colitis by prompting IL-10 production
Lei Yu et al.
CELL DEATH & DISEASE (2018)
Gastric cancer mesenchymal stem cells derived IL-8 induces PD-L1 expression in gastric cancer cells via STAT3/mTOR-c-Myc signal axis
Li Sun et al.
CELL DEATH & DISEASE (2018)
Blocking immunoinhibitory receptor LILRB2 reprograms tumor-associated myeloid cells and promotes antitumor immunity
Hui-Ming Chen et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Targeting macrophages: therapeutic approaches in cancer
Luca Cassetta et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
Targeting Macrophage-Recruiting Chemokines as a Novel Therapeutic Strategy to Prevent the Progression of Solid Tumors
David Argyle et al.
FRONTIERS IN IMMUNOLOGY (2018)
Regulatory NLRs Control the RLR-Mediated Type I Interferon and Inflammatory Responses in Human Dendritic Cells
Tunde Fekete et al.
FRONTIERS IN IMMUNOLOGY (2018)
TGF-β promotes fibrosis after severe acute kidney injury by enhancing renal macrophage infiltration
Sungjin Chung et al.
JCI INSIGHT (2018)
Blocking the CCL2-CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model
Kun-Yu Teng et al.
MOLECULAR CANCER THERAPEUTICS (2017)
Smad3 promotes cancer progression by inhibiting E4BP4-mediated NK cell development
Patrick Ming-Kuen Tang et al.
NATURE COMMUNICATIONS (2017)
Anti-CD47 Antibody As a Targeted Therapeutic Agent for Human Lung Cancer and Cancer Stem Cells
Liang Liu et al.
FRONTIERS IN IMMUNOLOGY (2017)
Inhibition of CD47 Effectively Targets Pancreatic Cancer Stem Cells via Dual Mechanisms
Michele Cioffi et al.
CLINICAL CANCER RESEARCH (2015)
Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1β, IFN-β, and IL-15 Pathways
Irene Mattiola et al.
JOURNAL OF IMMUNOLOGY (2015)
CSF-1 Receptor Signaling in Myeloid Cells
E. Richard Stanley et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2014)
Neutralizing Tumor-Promoting Chronic Inflammation: A Magic Bullet?
Lisa M. Coussens et al.
SCIENCE (2013)
Stabilization of HIF-2α Induces sVEGFR-1 Production from Tumor-Associated Macrophages and Decreases Tumor Growth in a Murine Melanoma Model
Julie M. Roda et al.
JOURNAL OF IMMUNOLOGY (2012)
The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors
Stephen B. Willingham et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Induction of regulatory T cells by macrophages is dependent on production of reactive oxygen species
Marina D. Kraaij et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
CXC chemokines: the regulatory link between inflammation and angiogenesis
P Romagnani et al.
TRENDS IN IMMUNOLOGY (2004)
Human macrophage activation programs induced by bacterial pathogens
GJ Nau et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)