Carbohydrate quality, fecal microbiota and cardiometabolic health in older adults: a cohort study

Review Nutrition & Dietetics

Changes in energy, macronutrient, and food consumption in 47 countries over the last 70 years (1950-2019): a systematic review and meta-analysis

Claudia Sikorski et al.

Summary: The study aimed to examine trends in dietary energy, macronutrient, and food consumption in different geographic regions. The findings revealed significant regional variations in dietary trends.

NUTRITION (2023)

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Review Nutrition & Dietetics

Importance of Carbohydrate Quality: What Does It Mean and How to Measure It?

Vanessa Campos et al.

Summary: Dietary carbohydrates are the main source of energy, but the metabolic effects and health impacts differ between simple and complex sugars. In addition to the amount consumed, the form of the carbohydrate and its processing level can affect energy efficiency and the risk of cardiovascular diseases. Metrics are needed to distinguish between carbohydrate-rich sources that contribute to chronic diseases and those that help prevent them.

JOURNAL OF NUTRITION (2022)

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Review Pharmacology & Pharmacy

Role of Butyrate, a Gut Microbiota Derived Metabolite, in Cardiovascular Diseases: A comprehensive narrative review

Parichehr Amiri et al.

Summary: Butyrate, a bacterial metabolite synthesized in the gut, shows potential therapeutic roles in cardiovascular diseases with various pharmacological activities.

FRONTIERS IN PHARMACOLOGY (2022)

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Article Multidisciplinary Sciences

16S rRNA and metagenomic shotgun sequencing data revealed consistent patterns of gut microbiome signature in pediatric ulcerative colitis

Wenxuan Zuo et al.

Summary: Using both 16S rRNA and metagenomic shotgun sequencing, we found that pediatric UC is associated with lower alpha diversity, higher beta diversity, and specific changes in microbial families and species compared to healthy children. We also demonstrated that 16S rRNA data can accurately predict pediatric UC, similar to shotgun data, but with lower cost and labor. These findings were confirmed in an independent dataset.

SCIENTIFIC REPORTS (2022)

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Article Endocrinology & Metabolism

Taxonomic and Functional Fecal Microbiota Signatures Associated With Insulin Resistance in Non-Diabetic Subjects With Overweight/Obesity Within the Frame of the PREDIMED-Plus Study

Alessandro Atzeni et al.

Summary: This study identified specific taxonomic and functional fecal microbiota signatures associated with insulin resistance in a non-diabetic population with overweight/obesity at high cardiovascular risk. The findings suggest that tailoring therapies based on specific fecal microbiota profiles could be a potential strategy to improve insulin sensitivity.

FRONTIERS IN ENDOCRINOLOGY (2022)

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Review Nutrition & Dietetics

Protective role of butyrate in obesity and diabetes: New insights

Arianna Mayorga-Ramos et al.

Summary: Studies have shown that short-chain fatty acids, particularly butyrate, play a crucial role in energy balance, inflammation regulation, and blood sugar control in the human body.

FRONTIERS IN NUTRITION (2022)

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Article Microbiology

Orally administered Odoribacter laneus improves glucose control and inflammatory profile in obese mice by depleting circulating succinate

Isabel Huber-Ruano et al.

Summary: The study reveals that gut microbiota is a significant source of elevated succinate in obese individuals. Therapeutic treatments with selected bacteria can reduce circulating succinate levels in obese mice, and Odoribacter laneus shows promise as a probiotic to deplete succinate and improve glucose tolerance.

MICROBIOME (2022)

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Article Nutrition & Dietetics

Association between ultra-processed food consumption and gut microbiota in senior subjects with overweight/obesity and metabolic syndrome

Alessandro Atzeni et al.

Summary: The consumption of ultra-processed foods (UPF) is associated with alterations in gut microbiota, reduced adherence to a Mediterranean diet, and higher total energy intake in senior subjects with overweight/obesity and metabolic syndrome. Furthermore, specific fecal microbiota taxa related to inflammatory gastro-intestinal diseases and low consumption of fruits and vegetables were positively associated with UPF consumption.

FRONTIERS IN NUTRITION (2022)

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Article Gastroenterology & Hepatology

Metabolism and Metabolic Disorders and the Microbiome: The Intestinal Microbiota Associated With Obesity, Lipid Metabolism, and Metabolic Health-Pathophysiology and Therapeutic Strategies

Judith Aron-Wisnewsky et al.

Summary: Studying the changes in the intestinal microbiome and their relationship with obesity, diabetes, and other metabolic diseases has provided insights into the mechanisms by which alterations in the microbiome contribute to these conditions. Recent research has focused on the effects of the microbiome on lipid metabolism and the development of strategies to modify the microbiome to reverse metabolic alterations. These approaches have shown promise in mouse models of obesity and metabolic disorders and hold potential for translating to human applications to improve metabolic health.

GASTROENTEROLOGY (2021)

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Article Multidisciplinary Sciences

Comparison between 16S rRNA and shotgun sequencing data for the taxonomic characterization of the gut microbiota

Francesco Durazzi et al.

Summary: This study compared the taxonomic results obtained from 16S rRNA gene sequencing and whole shotgun metagenomic sequencing, finding that shotgun sequencing is more capable of identifying rare taxa in chicken gut microbiota profiling. Additionally, the less abundant genera detected only by shotgun sequencing were found to be biologically meaningful.

SCIENTIFIC REPORTS (2021)

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Article Biochemical Research Methods

Multivariable association discovery in population-scale meta-omics studies

Himel Mallick et al.

Summary: The paper introduces a statistical model called MaAsLin 2 for multivariable associations in population-scale microbial community studies, which has been extensively validated. The authors highlight the importance and challenges of multivariable association analysis in microbiome research, and propose a new method to handle such complex data.

PLOS COMPUTATIONAL BIOLOGY (2021)

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Article Nutrition & Dietetics

Validity of the energy-restricted Mediterranean Diet Adherence Screener

Helmut Schroder et al.

Summary: The study found that the 17-item energy-restricted Mediterranean Adherence Screener (er-MEDAS) in the PREDIMED-Plus trial has moderate to good concurrent validity compared with a validated semiquantitative food frequency questionnaire (FFQ). An increase in the er-MEDAS score was associated with improvements in dietary and cardiometabolic profiles over time.

CLINICAL NUTRITION (2021)

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Article Gastroenterology & Hepatology

Elevated gut microbiome abundance of Christensenellaceae, Porphyromonadaceae and Rikenellaceae is associated with reduced visceral adipose tissue and healthier metabolic profile in Italian elderly

Teresa Tavella et al.

Summary: The study identified distinct compositional structures of the elderly gut microbiota associated with DXA parameters, diet, metabolic profiles, and cardio-metabolic risk factors.

GUT MICROBES (2021)

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Article Biochemistry & Molecular Biology

The MetaCyc database of metabolic pathways and enzymes - a 2019 update

Ron Caspi et al.

NUCLEIC ACIDS RESEARCH (2020)

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Article Nutrition & Dietetics

Carbohydrate quality changes and concurrent changes in cardiovascular risk factors: a longitudinal analysis in the PREDIMED-Plus randomized trial

Miguel A. Martinez-Gonzalez et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2020)

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Review Infectious Diseases

Non-alcoholic fatty liver diseases: from role of gut microbiota to microbial-based therapies

Hamed Ebrahimzadeh Leylabadlo et al.

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES (2020)

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Review Nutrition & Dietetics

Profile of the gut microbiota of adults with obesity: a systematic review

Louise Crovesy et al.

EUROPEAN JOURNAL OF CLINICAL NUTRITION (2020)

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Letter Biotechnology & Applied Microbiology

PICRUSt2 for prediction of metagenome functions

Gavin M. Douglas et al.

NATURE BIOTECHNOLOGY (2020)

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Review Biology

The human gut bacteria Christensenellaceae are widespread, heritable, and associated with health

Jillian L. Waters et al.

BMC BIOLOGY (2019)

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Article Endocrinology & Metabolism

Effect of a Lifestyle Intervention Program With Energy-Restricted Mediterranean Diet and Exercise on Weight Loss and Cardiovascular Risk Factors: One-Year Results of the PREDIMED-Plus Trial

Jordi Salas-Salvado et al.

DIABETES CARE (2019)

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Review Medicine, General & Internal

Carbohydrate quality and human health: a series of systematic reviews and meta-analyses

Andrew Reynolds et al.

LANCET (2019)

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Article Biology

Amplicon sequencing provides more accurate microbiome information in healthy children compared to culturing

Shashank Gupta et al.

COMMUNICATIONS BIOLOGY (2019)

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Article Nutrition & Dietetics

Association between dietary carbohydrate quality and the prevalence of obesity and hypertension

D-Y. Kim et al.

JOURNAL OF HUMAN NUTRITION AND DIETETICS (2018)

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Review Nutrition & Dietetics

Butyrate: A Double-Edged Sword for Health?

Hu Liu et al.

ADVANCES IN NUTRITION (2018)

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Article Microbiology

Shifts on Gut Microbiota Associated to Mediterranean Diet Adherence and Specific Dietary Intakes on General Adult Population

Izaskun Garcia-Mantrana et al.

FRONTIERS IN MICROBIOLOGY (2018)

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Article Multidisciplinary Sciences

Fecal microbiota transplantation confers beneficial metabolic effects of diet and exercise on diet-induced obese mice

Zi-Lun Lai et al.

SCIENTIFIC REPORTS (2018)

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Article Gastroenterology & Hepatology

The effect of heritability and host genetics on the gut microbiota and metabolic syndrome

Mi Young Lim et al.

GUT (2017)

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Review Genetics & Heredity

Microbiome and metabolic disease: revisiting the bacterial phylum Bacteroidetes

Elizabeth L. Johnson et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2017)

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Article Food Science & Technology

Pterostilbene-induced changes in gut microbiota composition in relation to obesity

Usune Etxeberria et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2017)

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Article Multidisciplinary Sciences

Validation of the Regicor Short Physical Activity Questionnaire for the Adult Population

Luis Molina et al.

PLOS ONE (2017)

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Review Multidisciplinary Sciences

Diet-microbiota interactions as moderators of human metabolism

Justin L. Sonnenburg et al.

NATURE (2016)

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Article Cardiac & Cardiovascular Systems

Glycemic index, glycemic load and glycemic response: An International Scientific Consensus Summit from the International Carbohydrate Quality Consortium (ICQC)

L. S. A. Augustin et al.

NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES (2015)

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Article Endocrinology & Metabolism

Specific gut microbiota features and metabolic markers in postmenopausal women with obesity

L. K. Brahe et al.

NUTRITION & DIABETES (2015)

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Article Nutrition & Dietetics

Carbohydrate quality, weight change and incident obesity in a Mediterranean cohort: the SUN Project

S. Santiago et al.

EUROPEAN JOURNAL OF CLINICAL NUTRITION (2015)

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Article Nutrition & Dietetics

Association between dietary carbohydrate intake quality and micronutrient intake adequacy in a Mediterranean cohort: the SUN (Seguimiento Universidad de Navarra) Project

Itziar Zazpe et al.

BRITISH JOURNAL OF NUTRITION (2014)

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Review Endocrinology & Metabolism

Carbohydrates and the human gut microbiota

Christophe Chassard et al.

CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2013)

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Article Multidisciplinary Sciences

Structure, function and diversity of the healthy human microbiome

Curtis Huttenhower et al.

NATURE (2012)

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Article Multidisciplinary Sciences

Human gut microbiome viewed across age and geography

Tanya Yatsunenko et al.

NATURE (2012)

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Article Nutrition & Dietetics

Relative validity of a semi-quantitative food-frequency questionnaire in an elderly Mediterranean population of Spain

Joan D. Fernandez-Ballarth et al.

BRITISH JOURNAL OF NUTRITION (2010)

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Article Public, Environmental & Occupational Health

Reproducibility of an FFQ validated in Spain

Carmen de la Fuente-Arrillaga et al.

PUBLIC HEALTH NUTRITION (2010)

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Article Endocrinology & Metabolism

International Tables of Glycemic Index and Glycemic Load Values: 2008

Fiona S. Atkinson et al.

DIABETES CARE (2008)

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Article Multidisciplinary Sciences

Microbial ecology - Human gut microbes associated with obesity

Ruth E. Ley et al.

NATURE (2006)

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Article Geosciences, Multidisciplinary

Logratio analysis and compositional distance

J Aitchison et al.

MATHEMATICAL GEOLOGY (2000)

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Carbohydrate quality, fecal microbiota and cardiometabolic health in older adults: a cohort study

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