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Rimao Wu et al.
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Had Zhang et al.
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Mirasbek Kuterbekov et al.
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Dung Trung Nguyen et al.
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Virpi Talman et al.
FRONTIERS IN CARDIOVASCULAR MEDICINE (2018)
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Amy Pointon et al.
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Amy Pointon et al.
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Tomohiro Hayakawa et al.
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Oksana Sirenko et al.
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Steven M. Paul et al.
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H. R. Lu et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
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Indroneal Banerjee et al.
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M Radisic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
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JA DiMasi et al.
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Mechanical force regulation of myofibroblast differentiation in cardiac fibroblasts
J Wang et al.
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