4.8 Article

Cooperation of local motions in the Hsp90 molecular chaperone ATPase mechanism

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Pharmacology & Pharmacy

Heat shock protein 90 inhibitors in the treatment of cancer: current status and future directions

Komal Jhaveri et al.

EXPERT OPINION ON INVESTIGATIONAL DRUGS (2014)

Article Chemistry, Multidisciplinary

Microsecond Folding and Domain Motions of a Spider Silk Protein Structural Switch

Julia Ries et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)

Article Biochemistry & Molecular Biology

Designed Hsp90 Heterodimers Reveal an Asymmetric ATPase-Driven Mechanism In Vivo

Parul Mishra et al.

MOLECULAR CELL (2014)

Article Biochemistry & Molecular Biology

Single-molecule spectroscopy of protein folding dynamics-expanding scope and timescales

Benjamin Schuler et al.

CURRENT OPINION IN STRUCTURAL BIOLOGY (2013)

Review Cell Biology

Chaperone machines for protein folding, unfolding and disaggregation

Helen Saibil

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)

Article Biochemistry & Molecular Biology

Integration of the accelerator Aha1 in the Hsp90 co-chaperone cycle

Jing Li et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)

Article Biochemistry & Molecular Biology

The 'active life' of Hsp90 complexes

Chrisostomos Prodromou

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2012)

Article Oncology

Hsp90 Molecular Chaperone Inhibitors: Are We There Yet?

Len Neckers et al.

CLINICAL CANCER RESEARCH (2012)

Editorial Material Chemistry, Medicinal

How Well Can Fragments Explore Accessed Chemical Space? A Case Study from Heat Shock Protein 90

Stephen D. Roughley et al.

JOURNAL OF MEDICINAL CHEMISTRY (2011)

Review Biophysics

Conformational dynamics of the molecular chaperone Hsp90

Kristin A. Krukenberg et al.

QUARTERLY REVIEWS OF BIOPHYSICS (2011)

Review Biochemistry & Molecular Biology

Tryptophan Residues: Scarce in Proteins but Strong Stabilizers of beta-Hairpin Peptides

Clara M. Santiveri et al.

BIOPOLYMERS (2010)

Article Biochemistry & Molecular Biology

Asymmetric Activation of the Hsp90 Dimer by Its Cochaperone Aha1

Marco Retzlaff et al.

MOLECULAR CELL (2010)

Review Cell Biology

HSP90 at the hub of protein homeostasis: emerging mechanistic insights

Mikko Taipale et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)

Article Multidisciplinary Sciences

Kinetics of chain motions within a protein-folding intermediate

Hannes Neuweiler et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Biochemical Research Methods

Hydrogen-Bond Driven Loop-Closure Kinetics in Unfolded Polypeptide Chains

Isabella Daidone et al.

PLOS COMPUTATIONAL BIOLOGY (2010)

Review Oncology

Targeting the dynamic HSP90 complex in cancer

Jane Trepel et al.

NATURE REVIEWS CANCER (2010)

Article Biochemistry & Molecular Biology

Spatially and kinetically resolved changes in the conformational dynamics of the Hsp90 chaperone machine

Christian Graf et al.

EMBO JOURNAL (2009)

Article Biochemistry & Molecular Biology

The large conformational changes of Hsp90 are only weakly coupled to ATP hydrolysis

Moritz Mickler et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)

Article Biochemistry & Molecular Biology

Dissection of the ATP-induced conformational cycle of the molecular chaperone Hsp90

Martin Hessling et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)

Article Multidisciplinary Sciences

Direct observation of ultrafast folding and denatured state dynamics in single protein molecules

Hannes Neuweiler et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Review Biochemistry & Molecular Biology

The Hsp90 molecular chaperone: an open and shut case for treatment

Laurence H. Pearl et al.

BIOCHEMICAL JOURNAL (2008)

Article Biochemistry & Molecular Biology

Species-Dependent Ensembles of Conserved Conformational States Define the Hsp90 Chaperone ATPase Cycle

Daniel R. Southworth et al.

MOLECULAR CELL (2008)

Article Biochemistry & Molecular Biology

Multiple conformations of E-coli Hsp90 in solution:: Insights into the conformational dynamics of Hsp90

Kristin A. Krukenberg et al.

STRUCTURE (2008)

Review Biochemistry & Molecular Biology

Identification and characterization of protein folding intermediates

Stefano Gianni et al.

BIOPHYSICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

Structure of an Hsp90-Cdc37-Cdk4 complex

Cara K. Vaughan et al.

MOLECULAR CELL (2006)

Review Oncology

Heat shock protein 90: A unique chemotherapeutic target

Sara B. Cullman et al.

SEMINARS IN ONCOLOGY (2006)

Article Multidisciplinary Sciences

Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex

MMU Ali et al.

NATURE (2006)

Review Oncology

HSP90 and the chaperoning of cancer

L Whitesell et al.

NATURE REVIEWS CANCER (2005)

Article Biochemistry & Molecular Biology

Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery

P Meyer et al.

EMBO JOURNAL (2004)

Article Biochemistry & Molecular Biology

Co-chaperone regulation of conformational switching in the Hsp90 ATPase cycle

G Siligardi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Independent ATPase activity of Hsp90 subunits creates a flexible assembly platform

SH McLaughlin et al.

JOURNAL OF MOLECULAR BIOLOGY (2004)

Review Biochemistry & Molecular Biology

Using photoinduced charge transfer reactions to study conformational dynamics of biopolymers at the single-molecule level

H Neuweiler et al.

CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2004)

Article Chemistry, Multidisciplinary

Fluorescence quenching of dyes by tryptophan: Interactions at atomic detail from combination of experiment and computer simulation

AC Vaiana et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)

Article Biochemistry & Molecular Biology

Dissection of the contribution of individual domains to the ATPase mechanism of Hsp90

H Wegele et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Oncology

Structure and Functional Relationships of Hsp90

Chrisostomos Prodromou et al.

CURRENT CANCER DRUG TARGETS (2003)

Article Biochemistry & Molecular Biology

Activation of the ATPase activity of Hsp90 by the stress-regulated cochaperone Aha1

B Panaretou et al.

MOLECULAR CELL (2002)

Article Biochemistry & Molecular Biology

N-terminal residues regulate the catalytic efficiency of the Hsp90 ATPase cycle

K Richter et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Coordinated ATP hydrolysis by the Hsp90 dimer

K Richter et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Multidisciplinary Sciences

Tryptophan zippers:: Stable, monomeric β-hairpins

AG Cochran et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)