相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling
Aashish Manglik et al.
CELL (2015)
Divergent Transducer-specific Molecular Efficacies Generate Biased Agonism at a G Protein-coupled Receptor ( GPCR)
Ryan T. Strachan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Tracing an allosteric pathway regulating the activity of the HslV protease
Lichi Shi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
What is biased efficacy? Defining the relationship between intrinsic efficacy and free energy coupling
H. Ongun Onaran et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2014)
Regulation of β2-Adrenergic Receptor Function by Conformationally Selective Single-Domain Intrabodies
Dean P. Staus et al.
MOLECULAR PHARMACOLOGY (2014)
The Dynamic Process of β2-Adrenergic Receptor Activation
Rie Nygaard et al.
CELL (2013)
Ligands Raise the Constraint That Limits Constitutive Activation in G Protein-coupled Opioid Receptors
Vanessa Vezzi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Adrenaline-activated structure of β2-adrenoceptor stabilized by an engineered nanobody
Aaron M. Ring et al.
NATURE (2013)
A three-stage biophysical screening cascade for fragment-based drug discovery
Ellene H. Mashalidis et al.
NATURE PROTOCOLS (2013)
Biased Signaling Pathways in β2-Adrenergic Receptor Characterized by 19F-NMR
Jeffrey J. Liu et al.
SCIENCE (2012)
Efficacy of the β2-adrenergic receptor is determined by conformational equilibrium in the transmembrane region
Yutaka Kofuku et al.
NATURE COMMUNICATIONS (2012)
Quantifying Ligand Bias at Seven-Transmembrane Receptors
Sudarshan Rajagopal et al.
MOLECULAR PHARMACOLOGY (2011)
Structure of a nanobody-stabilized active state of the β2 adrenoceptor
Soren G. F. Rasmussen et al.
NATURE (2011)
Crystal structure of the β2 adrenergic receptor-Gs protein complex
Soren G. F. Rasmussen et al.
NATURE (2011)
Multiple ligand-specific conformations of the β2-adrenergic receptor
Alem W. Kahsai et al.
NATURE CHEMICAL BIOLOGY (2011)
Two distinct conformations of helix 6 observed in antagonist-bound structures of a β1-adrenergic receptor
Rouslan Moukhametzianov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
MolProbity: all-atom structure validation for macromolecular crystallography
Vincent B. Chen et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)
PHENIX: a comprehensive Python-based system for macromolecular structure solution
Paul D. Adams et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)
Allosteric Coupling and Conformational Fluctuations in Proteins
H. Ongun Onaran et al.
CURRENT PROTEIN & PEPTIDE SCIENCE (2009)
Identification of two distinct inactive conformations of the β2-adrenergic receptor reconciles structural and biochemical observations
Ron O. Dror et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Phaser crystallographic software
Airlie J. McCoy et al.
JOURNAL OF APPLIED CRYSTALLOGRAPHY (2007)
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
Matthew R. Whorton et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
The quantitative analysis of drug-receptor interactions: a short history
D Colquhoun
TRENDS IN PHARMACOLOGICAL SCIENCES (2006)
Coot:: model-building tools for molecular graphics
P Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)
Complex ligand-protein systems:: a globally convergent iterative method for the n x m case
JR Pradines et al.
JOURNAL OF MATHEMATICAL BIOLOGY (2001)
Activation of the β2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6
JA Ballesteros et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
分享论文
