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Anna Piontek et al.
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Ling Huang et al.
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G. Krause et al.
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Jonas Protze et al.
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Rahel Philip et al.
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Xiangru Li et al.
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In vitro expansion and genetic modification of gastrointestinal stem cells in spheroid culture
Hiroyuki Miyoshi et al.
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Creation and biochemical analysis of a broad-specific claudin binder
Azusa Takahashi et al.
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Anna Veshnyakova et al.
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Johannes Schindelin et al.
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Zhijian Gao et al.
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Predicted expansion of the claudin multigene family
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Hiroshi Yamaguchi et al.
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Doerte Lohrberg et al.
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Molecular Determinants of the Interaction between Clostridium perfringens Enterotoxin Fragments and Claudin-3
Lars Winkler et al.
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Regulation of mucosal structure and barrier function in rat colon exposed to tumor necrosis factor alpha and interferon gamma in vitro: A novel model for studying the pathomechanisms of inflammatory bowel disease cytokines
Maren Amasheh et al.
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY (2009)
Domain mapping of a claudin-4 modulator, the C-terminal region of C-terminal fragment of Clostridium perfringens enterotoxin, by site-directed mutagenesis
Azusa Takahashi et al.
BIOCHEMICAL PHARMACOLOGY (2008)
Adherens and tight junctions: Structure, function and connections to the actin cytoskeleton
Andrea Hartsock et al.
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Changes in the expression of claudins in active ulcerative colitis
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S. Zeissig et al.
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K Becker et al.
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