☆ 4.7 Article

Personalization of Complex Vaginal Inserts of Ethylene Vinyl Acetate via 3D-Printing

ADVANCED MATERIALS TECHNOLOGIES (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Pharmacology & Pharmacy

Determination of feed forces to improve process understanding of Fused Deposition Modeling 3D printing and to ensure mass conformity of printed solid oral dosage forms

Nadine Gottschalk et al.

Summary: Fused Deposition Modeling is a suitable technique for personalized solid oral dosage forms. To address the complexity of formulation composition and limited mechanical understanding, a feed force tester was developed to determine suitable printing parameters and optimize the printing process.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2022)

添加到收藏夹

Article Pharmacology & Pharmacy

Toward a new generation of vaginal pessaries via 3D-printing: Concomitant mechanical support and drug delivery

Simone Eder et al.

Summary: This study explores the use of 3D printing to customize the mechanics and drug release of vaginal pessaries made from pharmaceutical grade thermoplastic polyurethanes (TPU). Soft hydrophobic TPU was found to be the most promising candidate for pessary customization, providing a wide range of mechanical parameters and allowing self-insertion. Hydrophobic TPUs also showed superior drug release performance, closer to the target value. 3D printing of TPU-based pessaries is an innovative strategy to create customized products that offer both mechanical support and pharmacological therapy.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2022)

添加到收藏夹

Article Instruments & Instrumentation

Fused deposition modeling three-dimensional printing of flexible polyurethane intravaginal rings with controlled tunable release profiles for multiple active drugs

Yufei Chen et al.

Summary: This study demonstrates the use of FDM 3D printing to fabricate intravaginal rings for controlled drug delivery. The release kinetics of different segments can be adjusted by controlling the printing parameters and fill densities.

DRUG DELIVERY AND TRANSLATIONAL RESEARCH (2022)

添加到收藏夹

Article Pharmacology & Pharmacy

Quality considerations on the pharmaceutical applications of fused deposition modeling 3D printing

Alice Melocchi et al.

Summary: 3D printing technology, particularly FDM, has rapidly become a hot topic in pharmaceutical research and media attention, with significant growth expected in 2020. Further development of FDM 2.0 process is needed to ensure the production of safe, high-quality personalized drug products.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

Tailoring amlodipine release from 3D printed tablets: Influence of infill patterns and wall thickness

Samiha Obeid et al.

Summary: This study investigated the impact of infill patterns and wall thickness on drug release of 3D-printed tablets, and the potential of using excipients to tailor drug release. Results showed that zigzag infill pattern and SSG excipient led to faster drug release, while HPMC HME 4 M had minimal effect on release rate. Additionally, decreasing wall thickness was associated with higher drug release. Proper selection of excipients and adjustment of infill patterns and wall thickness are important for tailoring drug release in FDM 3D printing.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

3D printed clotrimazole intravaginal ring for the treatment of recurrent vaginal candidiasis

Mattia Tiboni et al.

Summary: Vulvovaginal candidiasis is a common vaginal infection that typically affects women of reproductive age and is commonly treated with topical applications of imidazole drugs. Recent studies have shown the potential of 3D printing technology to create intravaginal rings that can provide sustained release of drugs for the treatment of this infection. This innovative approach offers a new method for improving patient compliance and long-term treatment options for recurrent cases.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

Extrusion-based 3D printing of oral solid dosage forms: Material requirements and equipment dependencies

S. Henry et al.

Summary: Extrusion-based 3D printing is being utilized for personalized medicine production in the medical field, but further research is needed to fully understand the interplay between material properties, process parameters, and printer-dependent variables for optimal printing behavior. This study characterizes various polymers and polymer-drug blends to determine their mechanical, thermal, and rheological properties, and links these properties to the quality of the end-product. Insights gained from this research will aid in accelerating pharmaceutical formulation development for 3D printed medications.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

添加到收藏夹

Review Pharmacology & Pharmacy

3D printing in personalized drug delivery: An overview of hot-melt extrusion-based fused deposition modeling

Nagireddy Dumpa et al.

Summary: Advancements in pharmaceutical technologies have led to the personalization of therapies over the last decade, with 3D printing emerging as a technique for manufacturing complex and customized dosage forms. Among the various 3D printing techniques, fused deposition modeling (FDM) is versatile and cost-effective, particularly in conjunction with hot-melt extrusion (HME) for filament preparation.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

Personalised urethra pessaries prepared by material extrusion-based additive manufacturing

Martin Spoerk et al.

Summary: Material extrusion-based additive manufacturing, commonly known as 3D printing, is considered crucial for personalized medical treatment. This study demonstrates the potential of utilizing 3D printing to customize vaginal inserts with complex structures, known as urethra pessaries, and adjusting their mechanical properties to relieve symptoms of urinary incontinence. The 3D-printed pessaries not only provide a viable alternative to commercial products, but also have the potential to effectively treat diverse patient groups, making pessary therapy accessible to every woman.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

Can filaments, pellets and powder be used as feedstock to produce highly drug-loaded ethylene-vinyl acetate 3D printed tablets using extrusion-based additive manufacturing?

Aseel Samaro et al.

Summary: Personalized medicine through 3D printing offers a promising approach for delivering the required drug dose based on the patient's profile. This study investigated the potential of different materials and 3D printing techniques in producing drug-loaded tablets, revealing the influence of material formulations and printing methods on the feasibility of drug delivery.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Novel polyester-based thermoplastic elastomers for 3D-printed long-acting drug delivery applications

Ioannis Koutsamanis et al.

Summary: This study addresses the limitation of flawlessly 3D-printable, yet biocompatible materials for long-acting drug delivery devices by introducing a novel non-biodegradable material TPC. Detailed analyses of TPC's 3D-printability and its interaction with progesterone were conducted, along with the establishment of TPC's drug-releasing properties. P4-loaded LADDDs based on TPC demonstrated pharmacologically relevant release rates, showing exceptional 3D-printability for a wide range of implant sizes and complex geometries.

JOURNAL OF CONTROLLED RELEASE (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

Controlled-Release from High-Loaded Reservoir-Type Systems-A Case Study of Ethylene-Vinyl Acetate and Progesterone

Ioannis Koutsamanis et al.

PHARMACEUTICS (2020)

添加到收藏夹

Review Pharmacology & Pharmacy

The ins and outs of drug-releasing vaginal rings: a literature review of expulsions and removals

Peter Boyd et al.

EXPERT OPINION ON DRUG DELIVERY (2020)

添加到收藏夹

Review Chemistry, Medicinal

A Graphical Review on the Escalation of Fused Deposition Modeling (FDM) 3D Printing in the Pharmaceutical Field

Alice Melocchi et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2020)

添加到收藏夹

Article Engineering, Manufacturing

Process-induced morphological features in material extrusion-based additive manufacturing of polypropylene

Sandra Petersmann et al.

ADDITIVE MANUFACTURING (2020)

添加到收藏夹

Article Polymer Science

Development of Porous Polyurethane Implants Manufactured via Hot-Melt Extrusion

Ioannis Koutsamanis et al.

POLYMERS (2020)

添加到收藏夹

Article Pharmacology & Pharmacy

Formulation and processability screening for the rational design of ethylene-vinyl acetate based intra-vaginal rings

I Koutsamanis et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)

添加到收藏夹

Article Materials Science, Multidisciplinary

Impact Optimization of 3D-Printed Poly(methyl methacrylate) for Cranial Implants

Sandra Petersmann et al.

MACROMOLECULAR MATERIALS AND ENGINEERING (2019)

添加到收藏夹

Article Biochemical Research Methods

Signal averaging improves signal-to-noise in OCT images: But which approach works best, and when?

Bernhard Baumann et al.

BIOMEDICAL OPTICS EXPRESS (2019)

添加到收藏夹

Article Pharmacology & Pharmacy

Mechanical testing methods for drug-releasing vaginal rings

Clare F. McCoy et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)

添加到收藏夹

Article Chemistry, Medicinal

Roadmap to 3D-Printed Oral Pharmaceutical Dosage Forms: Feedstock Filament Properties and Characterization for Fused Deposition Modeling

Johanna Aho et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2019)

添加到收藏夹

Article Materials Science, Composites

Effect of the printing bed temperature on the adhesion of parts produced by fused filament fabrication

Martin Spoerk et al.

PLASTICS RUBBER AND COMPOSITES (2018)

添加到收藏夹

Article Pharmacology & Pharmacy

Multi-purposable filaments of HPMC for 3D printing of medications with tailored drug release and timed-absorption

Hossam Kadry et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2018)

添加到收藏夹

Article Pharmacology & Pharmacy

3D printing of vaginal rings with personalized shapes for controlled release of progesterone

Junhui Fu et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2018)

添加到收藏夹

Article Polymer Science

Optimisation of the Adhesion of Polypropylene-Based Materials during Extrusion-Based Additive Manufacturing

Martin Spoerk et al.

POLYMERS (2018)

添加到收藏夹

Article Pharmacology & Pharmacy

Material Considerations for Fused-Filament Fabrication of Solid Dosage Forms

Evert Fuenmayor et al.

PHARMACEUTICS (2018)

添加到收藏夹

Article Engineering, Manufacturing

The effect of process parameters on tensile behavior of 3D printed flexible parts of ethylene vinyl acetate (EVA)

Narendra Kumar et al.

JOURNAL OF MANUFACTURING PROCESSES (2018)

添加到收藏夹

Review Obstetrics & Gynecology

Pessary use in stress urinary incontinence: a review of advantages, complications, patient satisfaction, and quality of life

Ghadeer Al-Shaikh et al.

INTERNATIONAL JOURNAL OF WOMENS HEALTH (2018)

添加到收藏夹

Review Chemistry, Multidisciplinary

Applications of ethylene vinyl acetate copolymers (EVA) in drug delivery systems

Christian Schneider et al.

JOURNAL OF CONTROLLED RELEASE (2017)

添加到收藏夹

Article Engineering, Manufacturing

Rate limits of additive manufacturing by fused filament fabrication and guidelines for high-throughput system design

Jamison Go et al.

ADDITIVE MANUFACTURING (2017)

添加到收藏夹

Article Pharmacology & Pharmacy

The Use of Cellulose Membrane to Eliminate Burst Release from Intravaginal Rings

Ignacio M. Helbling et al.

AAPS JOURNAL (2016)

添加到收藏夹

Article Pharmacology & Pharmacy

Ethylene vinyl acetate (EVA) as a new drug carrier for 3D printed medical drug delivery devices

Natalja Genina et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2016)

添加到收藏夹

Article Obstetrics & Gynecology

Quantitative analyses of variability in normal vaginal shape and dimension on MR images

Jiajia Luo et al.

INTERNATIONAL UROGYNECOLOGY JOURNAL (2016)

添加到收藏夹

Article Chemistry, Multidisciplinary

A novel approach to administration of peptides in women: Systemic absorption of a GnRH agonist via transvaginal ring delivery system

A. B. Kimball et al.

JOURNAL OF CONTROLLED RELEASE (2016)

添加到收藏夹

Article Chemistry, Multidisciplinary

3D scanning and 3D printing as innovative technologies for fabricating personalized topical drug delivery systems

Alvaro Goyanes et al.

JOURNAL OF CONTROLLED RELEASE (2016)

添加到收藏夹

Proceedings Paper Energy & Fuels

Optical constants of UV transparent EVA and the impact on the PV module output power under realistic irradiation

Malte R. Vogt et al.

PROCEEDINGS OF THE 6TH INTERNATIONAL CONFERENCE ON CRYSTALLINE SILICON PHOTOVOLTAICS (SILICONPV 2016) (2016)

添加到收藏夹

Article Pharmacology & Pharmacy

3D printing of modified-release aminosalicylate (4-ASA and 5-ASA) tablets

Alvaro Goyanes et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2015)

添加到收藏夹

Article Pharmacology & Pharmacy

Evaluation and optimization of progesterone release from intravaginal rings using response surface methodology

Ignacio M. Helbling et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2015)

添加到收藏夹

Article Pharmacology & Pharmacy

Fused-filament 3D printing (3DP) for fabrication of tablets

Alvaro Goyanes et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2014)

添加到收藏夹

Article Chemistry, Multidisciplinary

The Optimization of an Intravaginal Ring Releasing Progesterone Using a Mathematical Model

Ignacio M. Helbling et al.

PHARMACEUTICAL RESEARCH (2014)

添加到收藏夹

Article Green & Sustainable Science & Technology

Determination of thermal properties of crosslinked EVA encapsulant material in outdoor exposure by TSC and DSC methods

Kamel Agroui et al.

RENEWABLE ENERGY (2014)

添加到收藏夹

Review Chemistry, Multidisciplinary

Modeling of diffusion controlled drug delivery

Juergen Siepmann et al.

JOURNAL OF CONTROLLED RELEASE (2012)

添加到收藏夹

Article Instruments & Instrumentation

Development of a UC781 releasing polyethylene vinyl acetate vaginal ring

Christopher McConville et al.

DRUG DELIVERY AND TRANSLATIONAL RESEARCH (2012)

添加到收藏夹

Article Pharmacology & Pharmacy

Ethylene vinyl acetate as matrix for oral sustained release dosage forms produced via hot-melt extrusion

A. Almeida et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2011)

添加到收藏夹

Article Polymer Science

The thermal degradation of poly(vinyl acetate) and poly(ethylene-co-vinyl acetate), Part I:: Experimental study of the degradation mechanism

B. Rimez et al.

POLYMER DEGRADATION AND STABILITY (2008)

添加到收藏夹

Article Obstetrics & Gynecology

Baseline dimensions of the human vagina

Kurt T. Barnhart et al.

HUMAN REPRODUCTION (2006)

添加到收藏夹

Article Chemistry, Multidisciplinary

Influence of spinline stress on release properties of a coaxial controlled release device based on EVA polymers

H van Laarhoven et al.

PHARMACEUTICAL RESEARCH (2004)

添加到收藏夹

Article Chemistry, Multidisciplinary

Effect of supersaturation and crystallization phenomena on the release properties of a controlled release device based on EVA copolymer

JAH van Laarhoven et al.

JOURNAL OF CONTROLLED RELEASE (2002)

添加到收藏夹

Article Pharmacology & Pharmacy

In vitro release properties of etonogestrel and ethinyl estradiol from a contraceptive vaginal ring

JAH van Laarhoven et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2002)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.