The Neutrophil to Lymphocyte Ratio in Children with Bronchial Asthma

The discovery of an effective airway inflammation marker which correctly identifies the condition and phenotype of asthma still constitutes a significant challenge. The determination of NLR, that is, the ratio of neutrophils to lymphocytes, would overcome this challenge. The role of the neutrophil-lymphocytic index in the diagnosis of specific types of asthma is investigated in the present study. The results of laboratory tests of 482 pediatric patients were used for the analysis. The results of 107 children without allergic disease symptoms were selected for the control group. The mean NLR in patients with asthma was 3.42 +/- 4.05, and in the control group it was 1.94 +/- 1.91. The difference between the NLR in allergic and non-allergic asthma was statistically significant in the allergic asthma and control groups. There was no statistically significant difference between NLR and body temperature, BMI, and gender. The value of NLR was significantly higher in the blood of patients suffering from asthma compared to the control group. The NLR was the highest among patients with allergic asthma. The use of this blood test in daily practice may facilitate the diagnosis of asthma and differentiation between asthma types, especially when the results of other tests are inconclusive.

Automated summary

The determination of NLR can be used to diagnose specific types of asthma. Analysis of laboratory test results of 482 patients showed that the NLR value in asthma patients was significantly higher compared to the control group. Additionally, patients with allergic asthma had the highest NLR value. This blood test can assist in the diagnosis and differentiation of asthma types when other test results are inconclusive.