☆ 4.7 Review

Management and Prognosis of Acute Stroke in Atrial Fibrillation

JOURNAL OF CLINICAL MEDICINE (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Clinical Neurology

Intravenous Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of Direct Oral Anticoagulants

Thomas R. Meinel et al.

Summary: This study aimed to determine the risk of symptomatic intracranial hemorrhage (sICH) associated with the use of intravenous thrombolysis (IVT) in patients with recent intake of direct oral anticoagulants (DOACs) after ischemic stroke. The findings suggest that there is no excessive harm associated with off-label IVT in selected patients after ischemic stroke with recent DOAC ingestion.

JAMA NEUROLOGY (2023)

添加到收藏夹

Article Clinical Neurology

European Stroke Organisation (ESO) expedited recommendation on tenecteplase for acute ischaemic stroke

Sonia Alamowitch et al.

Summary: Four recent randomised-controlled clinical trials compare tenecteplase and alteplase in acute ischaemic stroke patients, with three showing non-inferiority. An expedited recommendation process based on the GRADE framework was conducted by the ESO. Recommendations were provided based on systematic reviews and meta-analyses, with expert consensus statements for areas with insufficient evidence. Tenecteplase at a dose of 0.25 mg/kg is recommended as a safe and effective alternative to alteplase for eligible AIS patients within 4.5 hours. However, a dose of 0.40 mg/kg is not recommended. Tenecteplase may be preferred over alteplase for certain patient groups. IVT with tenecteplase is also recommended for large vessel occlusion AIS patients within 4.5 hours. For AIS patients on awakening or with unknown onset, IVT with tenecteplase is not recommended.

EUROPEAN STROKE JOURNAL (2023)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Outcomes of patients with atrial fibrillation and ischemic stroke while on oral anticoagulation

Alexander P. Benz et al.

Summary: This study aimed to investigate the prognosis of patients with atrial fibrillation (AF) and ischemic stroke while on oral anticoagulation. The results showed that among the 1163 patients who had a post-randomization ischemic stroke while on study medication, 7.0% had a recurrent ischemic stroke within 1 year, and the all-cause mortality rate within 3 months was 12.4%.

EUROPEAN HEART JOURNAL (2023)

添加到收藏夹

Article Medicine, General & Internal

Recent Vitamin K Antagonist Use and Intracranial Hemorrhage After Endovascular Thrombectomy for Acute Ischemic Stroke

Brian Mac Grory et al.

Summary: The use of oral vitamin K antagonists (VKAs) may increase the risk of complications for patients undergoing endovascular thrombectomy for acute ischemic stroke caused by large vessel occlusion. Recent use of VKAs with an international normalized ratio (INR) greater than 1.7 is associated with a significantly higher risk of symptomatic intracranial hemorrhage (sICH) compared to no use of anticoagulants.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2023)

添加到收藏夹

Article Medicine, General & Internal

The third Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral HaemorrhageTrial (INTERACT3) an international, stepped wedge cluster randomised controlled trial

Lu Ma et al.

Summary: Implementing a goal-directed care bundle that focuses on early intensive blood pressure lowering, strict glucose control, antipyrexia, and rapid reversal of anticoagulation can improve outcomes for patients with acute intracerebral haemorrhage. This approach resulted in improved functional recovery and reduced serious adverse events in patients.

LANCET (2023)

添加到收藏夹

Article Medicine, General & Internal

Early versus Later Anticoagulation for Stroke with Atrial Fibrillation

Urs Fischer et al.

Summary: This study aimed to compare the effect of early initiation versus later initiation of direct oral anticoagulants (DOACs) on acute ischemic stroke in patients with atrial fibrillation. The results showed that there was no significant difference in the incidence of recurrent ischemic stroke, systemic embolism, major extracranial bleeding, symptomatic intracranial hemorrhage, or vascular death within 30 days between early and later use of DOACs.

NEW ENGLAND JOURNAL OF MEDICINE (2023)

添加到收藏夹

Article Clinical Neurology

Early Minimally Invasive Removal of Intracerebral Hemorrhage (ENRICH): Study protocol for a multi-centered two-arm randomized adaptive trial

Jonathan J. J. Ratcliff et al.

Summary: This study aims to evaluate the benefits of the minimally invasive trans-sulcal parafascicular surgery (MIPS) approach for the treatment of intracerebral hemorrhage (ICH). The results of this study will provide level-I evidence to guide the acute treatment of ICH.

FRONTIERS IN NEUROLOGY (2023)

添加到收藏夹

Article Medicine, General & Internal

Major Cardiovascular Events After Spontaneous Intracerebral Hemorrhage by Hematoma Location

Nils Jensen Boe et al.

Summary: Survivors of spontaneous intracerebral hemorrhage have an increased risk of major cardiovascular events. This cohort study found that patients with lobar intracerebral hemorrhage had a higher risk of subsequent major cardiovascular events, primarily due to an increased risk of recurrent intracerebral hemorrhage. This study highlights the importance of secondary intracerebral hemorrhage prevention strategies in patients with lobar intracerebral hemorrhage.

JAMA NETWORK OPEN (2023)

添加到收藏夹

Article Pharmacology & Pharmacy

Trends in the use of oral anticoagulants, antiplatelets and statins in four European countries: a population-based study

Luis A. Garcia Rodriguez et al.

Summary: The prevalence of antithrombotic use decreased in the UK, Region of Southern Denmark, Udine, and Spain between 2010 and 2018, mainly due to a reduction in low-dose aspirin use. Statin use remained constant in the UK and increased gradually in the Region of Southern Denmark, Udine, and Spain.

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2022)

添加到收藏夹

Article Medicine, General & Internal

Association of Recent Use of Non-Vitamin K Antagonist Oral Anticoagulants With Intracranial Hemorrhage Among Patients With Acute Ischemic Stroke Treated With Alteplase

Wayneho Kam et al.

Summary: This study aims to evaluate the safety and functional outcomes of intravenous alteplase in patients with acute ischemic stroke who were taking non-vitamin K antagonist oral anticoagulants (NOACs) prior to stroke, and compare the outcomes with patients who were not taking long-term anticoagulants.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2022)

添加到收藏夹

Article Clinical Neurology

Effects of stroke etiology on angiographic success in patients undergoing mechanical thrombectomy

Cigdem Deniz et al.

Summary: In this study, the relationship between stroke etiology and recanalization success with endovascular treatment in patients with acute ischemic stroke was investigated. The results showed that recanalization success and clinical outcomes did not differ significantly in patients with different etiologies, but the mortality rate was higher in patients with atherosclerotic etiology.

NEUROLOGICAL SCIENCES (2022)

添加到收藏夹

Article Clinical Neurology

Aetiology, secondary prevention strategies and outcomes of ischaemic stroke despite oral anticoagulant therapy in patients with atrial fibrillation

Alexandros A. Polymeris et al.

Summary: This study investigated the causes, preventive strategies, and outcomes of stroke in atrial fibrillation patients despite anticoagulation. The results showed that stroke had diverse causes, and some patients experienced cardioembolism despite sufficient anticoagulation. Treatment with DOAC was associated with better outcomes compared to VKA, while adding antiplatelets was linked to worse outcomes in high-risk patients. These findings suggest the need for individualized and novel preventive strategies.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2022)

添加到收藏夹

Article Clinical Neurology

Comparison of tenecteplase with alteplase for the early treatment of ischaemic stroke in the Melbourne Mobile Stroke Unit (TASTE-A): a phase 2, randomised, open-label trial

Andrew Bivard et al.

Summary: The use of tenecteplase in a mobile stroke unit in Melbourne, Australia resulted in superior reperfusion compared to alteplase upon hospital arrival, with no safety concerns.

LANCET NEUROLOGY (2022)

添加到收藏夹

Review Clinical Neurology

Review of Long-Term Blood Pressure Control After Intracerebral Hemorrhage: Challenges and Opportunities

Michael T. Mullen et al.

Summary: Blood pressure is the most important modifiable risk factor for intracerebral hemorrhage. Early use of medication to achieve blood pressure control is beneficial for acute ICH recovery. Long-term use of oral antihypertensive drugs can achieve lower blood pressure goals. Sustained reduction in blood pressure is more important than the choice of antihypertensive agents.

STROKE (2022)

添加到收藏夹

Article Clinical Neurology

Risk of Cerebrovascular Events in Intracerebral Hemorrhage Survivors With Atrial Fibrillation: A Nationwide Cohort Study

Peter Bronnum Nielsen et al.

Summary: The study found that patients with ICH and AF have a high risk of cerebrovascular ischemic events and a very high risk of all-cause death one year after the incident. Further clinical trials are needed to determine the optimal stroke prevention treatment for ICH survivors with AF.

STROKE (2022)

添加到收藏夹

Article Clinical Neurology

Recurrent Ischemic Stroke and Bleeding in Patients With Atrial Fibrillation Who Suffered an Acute Stroke While on Treatment With Nonvitamin K Antagonist Oral Anticoagulants: The RENO-EXTEND Study

Maurizio Paciaroni et al.

Summary: Patients with atrial fibrillation who suffer a stroke despite being on nonvitamin K antagonist oral anticoagulant therapy face a high risk of recurrent ischemic stroke and bleeding. Further research is needed to improve secondary prevention by investigating the mechanisms of recurrent ischemic stroke and bleeding.

STROKE (2022)

添加到收藏夹

Article Clinical Neurology

2022 Guideline for the Management of Patients With Spontaneous Intracerebral Hemorrhage: A Guideline From the American Heart Association/American Stroke Association

Steven M. Greenberg et al.

STROKE (2022)

添加到收藏夹

Article Clinical Neurology

Advancing the Surgical Treatment of Intracerebral Hemorrhage: Study Design and Research Directions

Ruben Dammers et al.

Summary: This narrative review discusses the study design aspects for surgical treatment research in patients with spontaneous acute intracerebral hemorrhage (ICH). Defining the primary endpoint relevant to the intervention being investigated and the timing of its assessment are emphasized. Compared to patients with acute ischemic stroke, patients with spontaneous acute ICH may have a longer recovery period. Efficient patient recruitment and deferred consent for disabled and critically ill patients are crucial. It is appropriate to conduct analysis of treatment effect adjusted for predefined covariables and urgent assessment is needed for the definition and use of minimally invasive surgery in relation to ICH. This review advocates for studies to be pragmatic and adhere to IDEAL recommendations and CONSORT guidelines.

WORLD NEUROSURGERY (2022)

添加到收藏夹

Review Clinical Neurology

Characterising acute ischaemic stroke thrombi: insights from histology, imaging and emerging impedance-based technologies

Smita Patil et al.

Summary: This article reviews the impact of thrombus composition on the treatment of acute ischaemic stroke (AIS) and discusses the application of current and emerging imaging technologies in diagnosing and detecting thrombus composition. The study found that thrombus composition is closely related to treatment success, but there is currently no definitive conclusion. Therefore, further research and the use of new technologies are needed to guide the optimal treatment approach.

STROKE AND VASCULAR NEUROLOGY (2022)

添加到收藏夹

Article Medicine, General & Internal

Risk Factors Associated With Mortality and Neurologic Disability After Intracerebral Hemorrhage in a Racially and Ethnically Diverse Cohort

Daniel Woo et al.

Summary: This cohort study validates the elements of the ICH score and suggests that additional baseline and interim patient characteristics are associated with variation in the 3-month outcome.

JAMA NETWORK OPEN (2022)

添加到收藏夹

Article Clinical Neurology

Intravenous Thrombolysis with Tenecteplase for the Treatment of Acute Ischemic Stroke

Georgios Tsivgoulis et al.

Summary: Comparing the safety and efficacy of tenecteplase versus alteplase in AIS patients, it was found that tenecteplase was associated with better 3-month clinical outcomes without an increased risk of symptomatic intracranial bleeding.

ANNALS OF NEUROLOGY (2022)

添加到收藏夹

Editorial Material Medicine, General & Internal

What is the right drug for insomnia disorder?

Myrto T. Samara

LANCET (2022)

添加到收藏夹

Review Clinical Neurology

Effectiveness and Safety of Antithrombotic Medication in Patients With Atrial Fibrillation and Intracranial Hemorrhage: Systematic Review and Meta-Analysis

Elena Ivany et al.

Summary: In nontraumatic ICrH survivors with atrial fibrillation, OAC therapy is associated with a reduced risk of thromboembolic events and all-cause mortality without significantly increasing risk of recurrent ICrH.

STROKE (2022)

添加到收藏夹

Article Hematology

Point-of-Care Assessment of Direct Oral Anticoagulation in Acute Ischemic Stroke: Protocol for a Prospective Observational Diagnostic Accuracy Study

Annahita Sedghi et al.

Summary: This study aims to determine if hyperacute point-of-care assessment of clotting time in whole blood can accurately identify the need for DOAC pretreatment in stroke patients, which is crucial for swift delivery of IVT treatment.

THROMBOSIS AND HAEMOSTASIS (2022)

添加到收藏夹

Review Hematology

Safety and efficacy of endovascular thrombectomy in acute ischemic stroke treated with anticoagulants: a systematic review and meta-analysis

Jia-Hung Chen et al.

Summary: In this study, the safety and efficacy of endovascular thrombectomy (EVT) in acute ischemic stroke (AIS) patients receiving oral anticoagulants (OACs) were examined. The results showed that compared to direct oral anticoagulants (DOACs), the use of vitamin K antagonists (VKAs) was associated with a higher risk of symptomatic intracranial hemorrhage (sICH) and mortality after EVT.

THROMBOSIS JOURNAL (2022)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Early Versus Delayed Non-Vitamin K Antagonist Oral Anticoagulant Therapy After Acute Ischemic Stroke in Atrial Fibrillation (TIMING): A Registry-Based Randomized Controlled Noninferiority Study

Jonas Oldgren et al.

Summary: This study compared the efficacy and safety of early versus delayed initiation of non-vitamin K antagonist oral anticoagulants (NOACs) in patients with acute ischemic stroke and atrial fibrillation. The results showed that early initiation of NOAC after acute stroke was noninferior to delayed initiation in terms of preventing recurrent ischemic stroke, symptomatic intracerebral hemorrhage, or all-cause mortality. The early initiation group had numerically lower rates of ischemic stroke and death, and no symptomatic intracerebral hemorrhages were observed.

CIRCULATION (2022)

添加到收藏夹

Article Clinical Neurology

Global epidemiology of atrial fibrillation: An increasing epidemic and public health challenge

Giuseppe Lippi et al.

Summary: Atrial fibrillation is the most frequent cardiac arrhythmia and is increasing in incidence and prevalence worldwide, especially in countries with middle socio-demographic index. The condition poses a significant economic burden and public health challenge in the future.

INTERNATIONAL JOURNAL OF STROKE (2021)

添加到收藏夹

Article Clinical Neurology

Prior Anticoagulation in Patients with Ischemic Stroke and Atrial Fibrillation

Thomas R. Meinel et al.

Summary: In patients with atrial fibrillation, prior treatment with direct oral anticoagulants (DOACs) may be associated with lower stroke severity at onset and lower rates of intravenous thrombolysis, leading to better functional outcomes at 3 months.

ANNALS OF NEUROLOGY (2021)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS)

Gerhard Hindricks et al.

EUROPEAN HEART JOURNAL (2021)

添加到收藏夹

Article Clinical Neurology

Endovascular stroke treatment in orally anticoagulated patients: an analysis from the German Stroke Registry-Endovascular Treatment

Clemens Kuepper et al.

Summary: The study analyzed data from the German Stroke Registry-Endovascular Treatment and found that endovascular treatment can be safely and successfully performed in orally anticoagulated stroke patients, although the frequency of good outcomes at 3 months was lower in these patients.

JOURNAL OF NEUROLOGY (2021)

添加到收藏夹

Review Clinical Neurology

Intravenous Thrombolysis With Tenecteplase in Patients With Large Vessel Occlusions Systematic Review and Meta-Analysis

Aristeidis H. Katsanos et al.

Summary: The study found that acute ischemic stroke patients with large vessel occlusions receiving intravenous thrombolysis with tenecteplase had significantly better recanalization and clinical outcomes compared to patients receiving alteplase.

STROKE (2021)

添加到收藏夹

Article Clinical Neurology

Importance of Occlusion Site for Thrombectomy Technique in Stroke Comparison Between Aspiration and Stent Retriever

Marie Louise E. Bernsen et al.

Summary: Thrombectomy with stent retriever and direct aspiration are equally effective in treating anterior circulation acute ischemic stroke, with direct aspiration achieving higher reperfusion rates and shorter procedure times. There were no significant differences in functional outcomes, periprocedural complications, or mortality between the two treatment techniques.

STROKE (2021)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Individual Patient Data from the Pivotal Randomized Controlled Trials of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation (COMBINE AF): Design and Rationale From the COMBINE AF (A Collaboration between Multiple institutions to Better Investigate Non-vitamin K antagonist oral anticoagulant use in Atrial Fibrillation) Investigators

Anthony P. Carnicelli et al.

Summary: The COMBINE AF project combines individual patient data from multiple trials to better understand the use of oral anticoagulants in patients with atrial fibrillation, with a focus on uncommon outcomes and patient subgroups. The research will use network meta-analysis to investigate the relative efficacy and safety of NOACs versus warfarin.

AMERICAN HEART JOURNAL (2021)

添加到收藏夹

Review Clinical Neurology

Recanalisation therapies for acute ischaemic stroke in patients on direct oral anticoagulants

David J. Seiffge et al.

Summary: This review discusses the primary therapeutic option for stroke prevention in atrial fibrillation patients, Direct Oral Anticoagulants (DOACs); it evaluates different approaches to patient selection, including time since last DOAC intake, drug-specific coagulation assays, and the use of reversal agents; precision medicine using a tailored approach seems to be a reasonable choice based on clinicoradiological information, anticoagulant activity, and the use of specific reversal agents only if necessary.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2021)

添加到收藏夹

Review Clinical Neurology

Hemorrhagic Transformation After Ischemic Stroke: Mechanisms and Management

Ji Man Hong et al.

Summary: This review outlines the pathophysiological mechanisms of symptomatic hemorrhagic transformation (HT) after acute ischemic stroke and discusses factors related to HT after reperfusion therapy, proposing prevention and treatment strategies like blood pressure control.

FRONTIERS IN NEUROLOGY (2021)

添加到收藏夹

Article Clinical Neurology

Stroke Etiology and Outcomes after Endovascular Thrombectomy: Results from the SITS Registry and a Meta-Analysis

Marius Matusevicius et al.

Summary: From the SITS thrombectomy register, we observed a lower chance of reperfusion and worse outcomes after thrombectomy in patients with LAA compared to CE etiology, despite more favorable baseline characteristics. In contrast, the meta-analysis did not find any difference between etiologies with aggregate data.

JOURNAL OF STROKE (2021)

添加到收藏夹

Review Clinical Neurology

Direct mechanical thrombectomy without intravenous thrombolysis versus bridging therapy for acute ischemic stroke: A meta-analysis of randomized controlled trials

Anna Podlasek et al.

Summary: A meta-analysis comparing direct mechanical thrombectomy and bridging therapy in acute ischemic stroke showed no difference in good functional outcome at 90 days, but direct mechanical thrombectomy reduced successful reperfusion and any intracranial hemorrhage. The non-inferiority margin was set at 4%.

INTERNATIONAL JOURNAL OF STROKE (2021)

添加到收藏夹

Article Clinical Neurology

Ischaemic stroke on anticoagulation therapy and early recurrence in acute cardioembolic stroke: the IAC study

Shadi Yaghi et al.

Summary: Despite receiving anticoagulation therapy, atrial fibrillation patients who suffer from ischemic stroke may still have a higher risk of recurrent ischemic events. Switching anticoagulant classes does not reduce the risk of recurrent ischemic events or symptomatic intracranial hemorrhage.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2021)

添加到收藏夹

Article Medicine, General & Internal

Left Atrial Appendage Occlusion during Cardiac Surgery to Prevent Stroke

Richard P. Whitlock et al.

Summary: Surgical occlusion of the left atrial appendage has been shown to reduce the risk of ischemic stroke or systemic embolism in patients with atrial fibrillation undergoing cardiac surgery, with no significant difference in perioperative complications between the occlusion and non-occlusion groups.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

添加到收藏夹

Review Clinical Neurology

Hemorrhagic Transformation in Ischemic Stroke and the Role of Inflammation

Elena Spronk et al.

Summary: Hemorrhagic transformation is a common complication in acute ischemic stroke patients, with factors such as stroke severity, reperfusion therapy, hypertension, hyperglycemia, and age increasing the risk. Inflammation and the immune system play important roles in BBB disruption and HT, with therapies targeting these pathways being potential strategies to reduce the risk of HT.

FRONTIERS IN NEUROLOGY (2021)

添加到收藏夹

Article Clinical Neurology

Risks of recurrent stroke and all serious vascular events after spontaneous intracerebral haemorrhage: pooled analyses of two population-based studies

Linxin Li et al.

Summary: This study analyzed the risks of recurrent ICH, ischaemic stroke, and other serious vascular events in patients with spontaneous ICH, showing differences in risks based on ICH location and comorbid atrial fibrillation. These data enable risk stratification of patients in clinical practice and ongoing randomized trials.

LANCET NEUROLOGY (2021)

添加到收藏夹

Review Clinical Neurology

Surgical Evacuation of Intracerebral Hemorrhage The Potential Importance of Timing

Christopher P. Kellner et al.

STROKE (2021)

添加到收藏夹

Review Clinical Neurology

2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack: A Guideline From the American Heart Association/American Stroke Association

Dawn O. Kleindorfer et al.

Summary: Additional digital content is available in the text.

STROKE (2021)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Antiplatelet therapy in patients with atrial fibrillation: a systematic review and meta-analysis of randomized trials

Alexander P. Benz et al.

Summary: Antiplatelets can modestly reduce stroke risk in atrial fibrillation patients not receiving oral anticoagulation, but there is a signal for increased stroke risk when used on top of anticoagulation therapy. Additionally, antiplatelet therapy significantly increases bleeding, moderately reduces myocardial infarction, and does not affect mortality regardless of background anticoagulation use.

EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY (2021)

添加到收藏夹

Review Clinical Neurology

Ischaemic stroke in anticoagulated patients with atrial fibrillation

Christoph Stretz et al.

Summary: Although anticoagulation significantly reduces the risk of stroke in patients with atrial fibrillation, a proportion of patients on anticoagulation still experience ischaemic stroke. Understanding the potential mechanisms of stroke despite anticoagulation is crucial in order to tailor individualized treatment strategies for secondary prevention.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2021)

添加到收藏夹

Article Clinical Neurology

European Stroke Organisation (ESO) guidelines on intravenous thrombolysis for acute ischaemic stroke

Eivind Berge et al.

Summary: Intravenous thrombolysis is the approved systemic reperfusion treatment for acute ischaemic stroke patients, with the ESO guidelines providing evidence-based recommendations. The guidelines highlight the importance of timely thrombolysis within 4.5 hours for improving functional outcomes, and recommend its use for specific patient subgroups such as those waking from sleep.

EUROPEAN STROKE JOURNAL (2021)

添加到收藏夹

Article Clinical Neurology

Ischemic Stroke despite Oral Anticoagulant Therapy in Patients with Atrial Fibrillation

David J. Seiffge et al.

ANNALS OF NEUROLOGY (2020)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Heart Disease and Stroke Statistics-2020 Update: A Report From the American Heart Association

Salim S. Virani et al.

CIRCULATION (2020)

添加到收藏夹

Article Clinical Neurology

Antagonizing dabigatran by idarucizumab in cases of ischemic stroke or intracranial hemorrhage in Germany-Updated series of 120 cases

Pawel Kermer et al.

INTERNATIONAL JOURNAL OF STROKE (2020)

添加到收藏夹

Article Clinical Neurology

MT in anticoagulated patients: Direct oral anticoagulants versus vitamin K antagonists

Vincent L'Allinec et al.

NEUROLOGY (2020)

添加到收藏夹

Article Clinical Neurology

Stroke reperfusion therapy following dabigatran reversal with idarucizumab in a national cohort

P. Alan Barber et al.

NEUROLOGY (2020)

添加到收藏夹

Article Clinical Neurology

Stroke Etiology Modifies the Effect of Endovascular Treatment in Acute Stroke

Steffen Tiedt et al.

STROKE (2020)

添加到收藏夹

Review Clinical Neurology

Safety of Intravenous Thrombolysis Among Patients Taking Direct Oral Anticoagulants A Systematic Review and Meta-Analysis

Shima Shahjouei et al.

STROKE (2020)

添加到收藏夹

Article Clinical Neurology

Endovascular Stroke Treatment and Risk of Intracranial Hemorrhage in Anticoagulated Patients

Thomas R. Meinel et al.

STROKE (2020)

添加到收藏夹

Article Clinical Neurology

Atrial Fibrillation-Associated Ischemic Stroke Patients With Prior Anticoagulation Have Higher Risk for Recurrent Stroke

Kanta Tanaka et al.

STROKE (2020)

添加到收藏夹

Article Clinical Neurology

Cortical superficial siderosis progression in cerebral amyloid angiopathy Prospective MRI study

Thanakit Pongpitakmetha et al.

NEUROLOGY (2020)

添加到收藏夹

Article Clinical Neurology

Endovascular Treatment for Acute Ischemic Stroke in Patients on Oral Anticoagulants Results From the MR CLEAN Registry

Robert-Jan B. Goldhoorn et al.

STROKE (2020)

添加到收藏夹

Editorial Material Clinical Neurology

Cerebral Amyloid Angiopathy Still a Syndromal Diagnosis

Geert Jan Biessels

STROKE (2020)

添加到收藏夹

Article Peripheral Vascular Disease

Risk Factors for Early Intracerebral Hemorrhage after Intravenous Thrombolysis with Alteplase

Xianda Lin et al.

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS (2020)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society in Collaboration With the Society of Thoracic Surgeons

Craig T. January et al.

CIRCULATION (2019)

添加到收藏夹

Article Medicine, General & Internal

Full Study Report of Andexanet Alfa for Bleeding Associated with Factor Xa Inhibitors

S. J. Connolly et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

添加到收藏夹

Article Clinical Neurology

Cerebral Ischemia in Patients on Direct Oral Anticoagulants Plasma Levels Are Associated With Stroke Severity

Kosmas Macha et al.

STROKE (2019)

添加到收藏夹

Article Clinical Neurology

Stroke severity in patients with preceding direct oral anticoagulant therapy as compared to vitamin K antagonists

Elias Auer et al.

JOURNAL OF NEUROLOGY (2019)

添加到收藏夹

Article Clinical Neurology

Epidemiology, Natural History, and Clinical Presentation of Large Vessel Ischemic Stroke

Robert C. Rennert et al.

NEUROSURGERY (2019)

添加到收藏夹

Article Clinical Neurology

Blood pressure control and clinical outcomes in acute intracerebral haemorrhage: a preplanned pooled analysis of individual participant data

Tom J. Moullaali et al.

LANCET NEUROLOGY (2019)

添加到收藏夹

Article Clinical Neurology

Causes and Risk Factors of Cerebral Ischemic Events in Patients With Atrial Fibrillation Treated With Non-Vitamin K Antagonist Oral Anticoagulants for Stroke Prevention: The RENo Study

Maurizio Paciaroni et al.

STROKE (2019)

添加到收藏夹

Article Clinical Neurology

Evidence that Tenecteplase Is Noninferior to Alteplase for Acute Ischemic Stroke: Meta-Analysis of 5 Randomized Trials

Adrian M. Burgos et al.

STROKE (2019)

添加到收藏夹

Review Neuroimaging

Prevalence of large vessel occlusion in patients presenting with acute ischemic stroke: a 10-year systematic review of the literature

Nikita Lakomkin et al.

JOURNAL OF NEUROINTERVENTIONAL SURGERY (2019)

添加到收藏夹

Article Clinical Neurology

European Stroke Organisation (ESO) - European Society for Minimally Invasive Neurological Therapy (ESMINT) Guidelines on Mechanical Thrombectomy in Acute Ischaemic StrokeEndorsed by Stroke Alliance for Europe (SAFE)

Guillaume Turc et al.

EUROPEAN STROKE JOURNAL (2019)

添加到收藏夹

Article Clinical Neurology

Antithrombotic treatment for secondary prevention of stroke and other thromboembolic events in patients with stroke or transient ischemic attack and non-valvular atrial fibrillation: A European Stroke Organisation guideline

Catharina J. M. Klijn et al.

EUROPEAN STROKE JOURNAL (2019)

添加到收藏夹

Article Clinical Neurology

Consensus statements and recommendations from the ESO-Karolinska Stroke Update Conference, Stockholm 11-13 November 2018

Niaz Ahmed et al.

EUROPEAN STROKE JOURNAL (2019)

添加到收藏夹

Article Clinical Neurology

European Stroke Organisation Guideline on Reversal of Oral Anticoagulants in Acute Intracerebral Haemorrhage

Hanne Christensen et al.

EUROPEAN STROKE JOURNAL (2019)

添加到收藏夹

Review Clinical Neurology

Atrial Fibrillation for the Neurologist: Preventing both Ischemic and Hemorrhagic Strokes

Elif Gokcal et al.

CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS (2018)

添加到收藏夹

Article Medicine, General & Internal

Tenecteplase versus Alteplase before Thrombectomy for Ischemic Stroke

B. C. V. Campbell et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

添加到收藏夹

Article Medicine, General & Internal

Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging

G. W. Albers et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

添加到收藏夹

Article Medicine, General & Internal

Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct

R. G. Nogueira et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

添加到收藏夹

Editorial Material Clinical Neurology

Optimal Blood Pressure After Intracerebral Hemorrhage: Still a Moving Target

Alejandro A. Rabinstein

STROKE (2018)

添加到收藏夹

Article Clinical Neurology

2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

William J. Powers et al.

STROKE (2018)

添加到收藏夹

Review Medicine, General & Internal

Resuming anticoagulants after anticoagulation-associated intracranial haemorrhage: systematic review and meta-analysis

Zien Zhou et al.

BMJ OPEN (2018)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Trevo 2000: Results of a Large Real-World Registry for Stent Retriever for Acute Ischemic Stroke

Mandy J. Binning et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2018)

添加到收藏夹

Review Neuroimaging

Correlation of imaging and histopathology of thrombi in acute ischemic stroke with etiology and outcome: a systematic review

Waleed Brinjikji et al.

JOURNAL OF NEUROINTERVENTIONAL SURGERY (2017)

添加到收藏夹

Article Clinical Neurology

Optimal Timing of Anticoagulant Treatment After Intracerebral Hemorrhage in Patients With Atrial Fibrillation

Johanna Pennlert et al.

STROKE (2017)

添加到收藏夹

Article Medicine, General & Internal

Association of Preceding Antithrombotic Treatment With Acute Ischemic Stroke Severity and In-Hospital Outcomes Among Patients With Atrial Fibrillation

Ying Xian et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2017)

添加到收藏夹

Article Neurosciences

Safety of Endovascular Intervention for Stroke on Therapeutic Anticoagulation: Multicenter Cohort Study and Meta-Analysis

Donna Kurowski et al.

JOURNAL OF STROKE & CEREBROVASCULAR DISEASES (2017)

添加到收藏夹

Review Medicine, General & Internal

The future of atrial fibrillation management: integrated care and stratified therapy

Paulus Kirchhof

LANCET (2017)

添加到收藏夹

Article Clinical Neurology

Cortical superficial siderosis multifocality in cerebral amyloid angiopathy A prospective study

Andreas Charidimou et al.

NEUROLOGY (2017)

添加到收藏夹

Article Clinical Neurology

Brain hemorrhage recurrence, small vessel disease type, and cerebral microbleeds A meta-analysis

Andreas Charidimou et al.

NEUROLOGY (2017)

添加到收藏夹

Article Medicine, General & Internal

Rivaroxaban with or without Aspirin in Stable Cardiovascular Disease

J. W. Eikelboom et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

添加到收藏夹

Article Medicine, General & Internal

Idarucizumab for Dabigatran Reversal - Full Cohort Analysis

Charles V. Pollack et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

添加到收藏夹

Review Clinical Neurology

Restarting Anticoagulant Therapy After Intracranial Hemorrhage A Systematic Review and Meta-Analysis

Santosh B. Murthy et al.

STROKE (2017)

添加到收藏夹

Review Clinical Neurology

Treatment and Outcome of Hemorrhagic Transformation After Intravenous Alteplase in Acute Ischemic Stroke: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association

Shadi Yaghi et al.

STROKE (2017)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Early Recurrence and Major Bleeding in Patients With Acute Ischemic Stroke and Atrial Fibrillation Treated With Non-Vitamin-K Oral Anticoagulants (RAF-NOACs) Study

Maurizio Paciaroni et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2017)

添加到收藏夹

Article Neurosciences

Safety of Endovascular Intervention for Stroke on Therapeutic Anticoagulation: Multicenter Cohort Study and Meta-Analysis

Donna Kurowski et al.

JOURNAL OF STROKE & CEREBROVASCULAR DISEASES (2017)

添加到收藏夹

Review Clinical Neurology

Thrombectomy in Acute Ischernic Stroke: Challenges to Procedural Success

Albert J. Yoo et al.

JOURNAL OF STROKE (2017)

添加到收藏夹

Article Clinical Neurology

Oral Anticoagulation and Functional Outcome after Intracerebral Hemorrhage

Alessandro Biffi et al.

ANNALS OF NEUROLOGY (2017)

添加到收藏夹

Article Clinical Neurology

Three-month risk-benefit profile of anticoagulation after stroke with atrial fibrillation: The SAMURAI-Nonvalvular Atrial Fibrillation (NVAF) study

Shoji Arihiro et al.

INTERNATIONAL JOURNAL OF STROKE (2016)

添加到收藏夹

Article Medicine, General & Internal

Stroke prevention in atrial fibrillation

Ben Freedman et al.

LANCET (2016)

添加到收藏夹

Article Clinical Neurology

Fresh frozen plasma versus prothrombin complex concentrate in patients with intracranial haemorrhage related to vitamin K antagonists (INCH): a randomised trial

Thorsten Steiner et al.

LANCET NEUROLOGY (2016)

添加到收藏夹

Article Clinical Neurology

Early start of DOAC after ischemic stroke Risk of intracranial hemorrhage and recurrent events

David J. Seiffge et al.

NEUROLOGY (2016)

添加到收藏夹

Article Medicine, General & Internal

Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage

Adnan I. Qureshi et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

添加到收藏夹

Article Clinical Neurology

Thrombus Histology Suggests Cardioembolic Cause in Cryptogenic Stroke

Tobias Boeckh-Behrens et al.

STROKE (2016)

添加到收藏夹

Article Clinical Neurology

Outcomes With Edoxaban Versus Warfarin in Patients With Previous Cerebrovascular Events Findings From ENGAGE AF-TIMI 48 (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48)

Natalia S. Rost et al.

STROKE (2016)

添加到收藏夹

Review Clinical Neurology

Cortical superficial siderosis: detection and clinical significance in cerebral amyloid angiopathy and related conditions

Andreas Charidimou et al.

BRAIN (2015)

添加到收藏夹

Review Clinical Neurology

Intra-Arterial Therapy for Acute Ischemic Stroke: a Golden Age

Pedro Telles Cougo-Pinto et al.

CURRENT TREATMENT OPTIONS IN NEUROLOGY (2015)

添加到收藏夹

Article Medicine, General & Internal

Association Between Blood Pressure Control and Risk of Recurrent Intracerebral Hemorrhage

Alessandro Biffi et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2015)

添加到收藏夹

Article Medicine, General & Internal

Thrombectomy within 8 Hours after Symptom Onset in Ischemic Stroke

T. G. Jovin et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

添加到收藏夹

Article Medicine, General & Internal

Randomized Assessment of Rapid Endovascular Treatment of Ischemic Stroke

M. Goyal et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

添加到收藏夹

Article Medicine, General & Internal

Endovascular Therapy for Ischemic Stroke with Perfusion-Imaging Selection

B. C. V. Campbell et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

添加到收藏夹

Article Medicine, General & Internal

Andexanet Alfa for the Reversal of Factor Xa Inhibitor Activity

Deborah M. Siegal et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

添加到收藏夹

Article Medicine, General & Internal

A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke

O. A. Berkhemer et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

添加到收藏夹

Article Clinical Neurology

Early Recurrence and Cerebral Bleeding in Patients With Acute Ischemic Stroke and Atrial Fibrillation Effect of Anticoagulation and Its Timing: The RAF Study

Maurizio Paciaroni et al.

STROKE (2015)

添加到收藏夹

Article Clinical Neurology

Cerebral microbleeds as a predictor of macrobleeds: what is the evidence?

Andreas Charidimou et al.

INTERNATIONAL JOURNAL OF STROKE (2014)

添加到收藏夹

Article Clinical Neurology

European Stroke Organisation (ESO) guidelines for the management of spontaneous intracerebral hemorrhage

Thorsten Steiner et al.

INTERNATIONAL JOURNAL OF STROKE (2014)

添加到收藏夹

Review Clinical Neurology

Long-term prognosis after intracerebral haemorrhage: systematic review and meta-analysis

Michael Tin Chung Poon et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2014)

添加到收藏夹

Article Medicine, General & Internal

Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials

Jonathan Emberson et al.

LANCET (2014)

添加到收藏夹

Article Medicine, General & Internal

Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials

Christian T. Ruff et al.

LANCET (2014)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

EHRA Practical Guide on the use of new oral anticoagulants in patients with non-valvular atrial fibrillation: executive summary

Hein Heidbuchel et al.

EUROPEAN HEART JOURNAL (2013)

添加到收藏夹

Article Clinical Neurology

Cortical superficial siderosis and intracerebral hemorrhage risk in cerebral amyloid angiopathy

Andreas Charidimou et al.

NEUROLOGY (2013)

添加到收藏夹

Article Medicine, General & Internal

Edoxaban versus Warfarin in Patients with Atrial Fibrillation

Robert P. Giugliano et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

添加到收藏夹

Article Clinical Neurology

INTERACT-2 Should Blood Pressure Be Aggressively Lowered Acutely After Intracerebral Hemorrhage?

Michael D. Hill et al.

STROKE (2013)

添加到收藏夹

Review Clinical Neurology

Hemorrhagic transformation: a review of the rate of hemorrhage in the major clinical trials of acute ischemic stroke

Eric S. Sussman et al.

FRONTIERS IN NEUROLOGY (2013)

添加到收藏夹

Article Medicine, General & Internal

Risks of Intracranial Hemorrhage Among Patients With Acute Ischemic Stroke Receiving Warfarin and Treated With Intravenous Tissue Plasminogen Activator

Ying Xian et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2012)

添加到收藏夹

Article Clinical Neurology

Rivaroxaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of ROCKET AF

Graeme J. Hankey et al.

LANCET NEUROLOGY (2012)

添加到收藏夹

Article Clinical Neurology

Apixaban versus aspirin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a predefined subgroup analysis from AVERROES, a randomised trial

Hans-Christoph Diener et al.

LANCET NEUROLOGY (2012)

添加到收藏夹

Article Clinical Neurology

Apixaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of the ARISTOTLE trial

J. Donald Easton et al.

LANCET NEUROLOGY (2012)

添加到收藏夹

Article Clinical Neurology

Predicting the Risk of Symptomatic Intracerebral Hemorrhage in Ischemic Stroke Treated With Intravenous Alteplase Safe Implementation of Treatments in Stroke (SITS) Symptomatic Intracerebral Hemorrhage Risk Score

Michael Mazya et al.

STROKE (2012)

添加到收藏夹

Article Clinical Neurology

Poor Prognosis in Warfarin-Associated Intracranial Hemorrhage Despite Anticoagulation Reversal

Dar Dowlatshahi et al.

STROKE (2012)

添加到收藏夹

Article Medicine, General & Internal

Apixaban versus Warfarin in Patients with Atrial Fibrillation

Christopher B. Granger et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

添加到收藏夹

Article Medicine, General & Internal

Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation

Manesh R. Patel et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

添加到收藏夹

Correction Clinical Neurology

Dabigatran compared with warfarin in patients with atrial fibrillation and previous transient ischaemic attack or stroke: a subgroup analysis of the RE-LY trial (vol 9, pg 1157, 2010)

H. C. Diener et al.

LANCET NEUROLOGY (2011)

添加到收藏夹

Review Clinical Neurology

Evolution of the Thrombolytic Treatment Window for Acute Ischemic Stroke

Andrew Stemer et al.

CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS (2010)

添加到收藏夹

Article Medicine, General & Internal

Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study

Martin J. O'Donnell et al.

LANCET (2010)

添加到收藏夹

Article Clinical Neurology

Dabigatran compared with warfarin in patients with atrial fibrillation and previous transient ischaemic attack or stroke: a subgroup analysis of the RE-LY trial

Hans Chnstoph Diener et al.

LANCET NEUROLOGY (2010)

添加到收藏夹

Article Clinical Neurology

Incidence, case fatality, and functional outcome of intracerebral haemorrhage overtime, according to age, sex, and ethnic origin: a systematic review and meta-analysis

Charlotte J. J. van Asch et al.

LANCET NEUROLOGY (2010)

添加到收藏夹

Article Medicine, General & Internal

Dabigatran versus Warfarin in Patients with Atrial Fibrillation.

Stuart J. Connolly et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

添加到收藏夹

Article Medicine, General & Internal

Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke

Werner Hacke et al.

NEW ENGLAND JOURNAL OF MEDICINE (2008)

添加到收藏夹

Article Clinical Neurology

Risk factors for intracerebral hemorrhage in a pooled prospective study

Jared D. Sturgeon et al.

STROKE (2007)

添加到收藏夹

Review Clinical Neurology

Spontaneous brain microbleeds: systematic review, subgroup analyses and standards for study design and reporting

Charlotte Cordonnier et al.

BRAIN (2007)

添加到收藏夹

Review Medicine, General & Internal

Meta-analysis: Antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation

Robert G. Hart et al.

ANNALS OF INTERNAL MEDICINE (2007)

添加到收藏夹

Article Clinical Neurology

Prior events predict cerebrovascular and coronary outcomes in the PROGRESS trial

Hisatomi Arima et al.

STROKE (2006)

添加到收藏夹

Article Clinical Neurology

Atrial fibrillation as a predictive factor for severe stroke and early death in 15,831 patients with acute ischaemic stroke

K Kimura et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2005)

添加到收藏夹

Article Clinical Neurology

Association of ischemic lesion patterns on early diffusion-weighted imaging with TOAST stroke subtypes

DW Kang et al.

ARCHIVES OF NEUROLOGY (2003)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.