4.7 Article

Association of ADP-Induced Whole-Blood Platelet Aggregation with Serum Low-Density Lipoprotein Cholesterol in Patients with Coronary Artery Disease When Receiving Maintenance Ticagrelor-Based Dual Antiplatelet Therapy

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Cardiac & Cardiovascular Systems

Dual antiplatelet therapy de-escalation in acute coronary syndrome: an individual patient meta-analysis

Jeehoon Kang et al.

Summary: This study compared the de-escalation strategy with standard dual-antiplatelet therapy in ACS patients using individual patient data meta-analysis. The de-escalation strategy was associated with decreased ischaemic and bleeding endpoints, with unguided de-escalation showing a greater reduction in bleeding risk.

EUROPEAN HEART JOURNAL (2023)

Letter Cardiac & Cardiovascular Systems

Influence of body size on platelet response to ticagrelor and prasugrel in patients with acute coronary syndromes

Gjin Ndrepepa et al.

CLINICAL RESEARCH IN CARDIOLOGY (2022)

Review Medicine, General & Internal

The Association between Low Levels of Low Density Lipoprotein Cholesterol and Intracerebral Hemorrhage: Cause for Concern?

Chen Gurevitz et al.

Summary: Excessive levels of LDL-C are a risk factor for atherosclerosis, but low LDL-C levels are associated with intracerebral hemorrhage. Individualized therapy should be considered for patients with high risk of ICH when aggressive LDL reduction is being considered.

JOURNAL OF CLINICAL MEDICINE (2022)

Article Medicine, General & Internal

Diurnal Variability of Platelet Aggregation in Patients with Myocardial Infarction Treated with Prasugrel and Ticagrelor

Piotr Adamski et al.

Summary: This study compared the diurnal variability of platelet reactivity between patients receiving prasugrel and ticagrelor after acute myocardial infarction (AMI). The results showed that ticagrelor had greater diurnal variability in platelet aggregation compared to prasugrel, and there was a continuous increase of platelet inhibition after the morning maintenance dose. Both drugs provided adequate antiplatelet effect early after AMI.

JOURNAL OF CLINICAL MEDICINE (2022)

Review Pharmacology & Pharmacy

A systematic review and meta-analysis of the effect of statin treatment on sVCAM-1 and sICAM-1

Angelo Zinellu et al.

Summary: This study aimed to evaluate the effect of statins on cell adhesion molecules. The results of a systematic review and meta-analysis showed that statins significantly reduced the concentrations of soluble vascular adhesion molecule and intercellular adhesion molecule. Subgroup analysis indicated that lipophilic statins had a more significant lowering effect.

EXPERT REVIEW OF CLINICAL PHARMACOLOGY (2022)

Article Medicine, General & Internal

Differences in Optimal Platelet Reactivity after Potent P2Y12 Inhibitor Treatment in Acute Coronary Syndrome Patients Undergoing Percutaneous Coronary Intervention

Kai Song et al.

Summary: This study compared the drug responses of reduced doses of prasugrel and ticagrelor in Korean ACS patients and found that these reduced doses resulted in lower platelet reactivity compared to conventional-dose clopidogrel. Prasugrel showed significantly lower platelet inhibition than ticagrelor.

JOURNAL OF CLINICAL MEDICINE (2022)

Review Medicine, General & Internal

Comparison of Current International Guidelines for the Management of Dyslipidemia

Sevda Aygun et al.

Summary: The dyslipidemia guidelines of the three major societies have been recently revised to prioritize lowering LDL-C levels. Although there are some differences in risk estimation systems and goals, the main principles and messages are consistent across the guidelines. To combat the epidemic of cardiovascular disease, it is crucial to focus on implementing these guidelines in our region.

JOURNAL OF CLINICAL MEDICINE (2022)

Review Biochemistry & Molecular Biology

Platelet Redox Imbalance in Hypercholesterolemia: A Big Problem for a Small Cell

Alessandro Morotti et al.

Summary: This article discusses the association between oxidative stress and hypercholesterolemia, as well as platelet hyperreactivity, and explores the impact of lipid-lowering therapies on thrombogenesis, emphasizing the significance of oxidative stress-related mechanisms in platelet function.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Article Cardiac & Cardiovascular Systems

Endothelial biomarkers and platelet reactivity on ticagrelor versus clopidogrel in patients after acute coronary syndrome with and without concomitant type 2 diabetes: a preliminary observational study

Bernadeta Chyrchel et al.

Summary: This study compared the effects of ticagrelor and clopidogrel on endothelial biomarkers and platelet reactivity in patients with acute coronary syndrome (ACS). The results showed that ticagrelor users had decreased platelet aggregation and soluble P-selectin levels compared to clopidogrel users. In addition, T2DM patients on ticagrelor had lower levels of soluble vascular cell adhesion molecule-1 compared to those on clopidogrel.

CARDIOVASCULAR DIABETOLOGY (2022)

Article Cardiac & Cardiovascular Systems

Low hemoglobin predicts high-platelet reactivity and major cardiovascular ischemic events at long-term follow-up among ACS patients receiving dual antiplatelet therapy with ticagrelor

Monica Verdoia et al.

Summary: This study showed that among patients on DAPT with ASA and ticagrelor after PCI for ACS, lower Hb levels are independently associated with a higher rate of HRPR and major ischemic events. However, the prognostic effect of HRPR was neutral across different Hb tertiles.

CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS (2021)

Review Biochemistry & Molecular Biology

Systematic Review and Meta-Analysis of the Effect of Statins on Circulating E-Selectin, L-Selectin, and P-Selectin

Angelo Zinellu et al.

Summary: Statins can effectively decrease circulating levels of cell adhesion molecules, including P-selectin, L-selectin, and E-selectin, which are involved in the pathogenesis of atherosclerosis. Research indicates that statins have a significant impact on reducing these selectins independently of baseline lipid profiles and other patient characteristics, potentially contributing to cardiovascular risk reduction.

BIOMEDICINES (2021)

Article Cardiac & Cardiovascular Systems

LDL cholesterol levels and in-hospital bleeding in patients on high-intensity antithrombotic therapy: findings from the CCC-ACS project

Qing Yang et al.

Summary: Evidence shows a non-linear association between LDL-C levels and major in-hospital bleeds in ACS patients, with higher risk at lower levels. Further studies are needed due to potential confounding factors.

EUROPEAN HEART JOURNAL (2021)

Article Cardiac & Cardiovascular Systems

Homocysteine levels and platelet reactivity in coronary artery disease patients treated with ticagrelor

Monica Verdoia et al.

NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES (2020)

Review Biochemistry & Molecular Biology

Influence of Cardiometabolic Risk Factors on Platelet Function

Cristina Barale et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Medicine, General & Internal

Increased platelet reactivity in dyslipidemic patients with coronary artery disease on dual anti-platelet therapy

Bernhard Jaeger et al.

ARCHIVES OF MEDICAL SCIENCE (2019)

Article Biotechnology & Applied Microbiology

Simvastatin Effects on Inflammation and Platelet Activation Markers in Hypercholesterolemia

Cristina Barale et al.

BIOMED RESEARCH INTERNATIONAL (2018)

Review Hematology

Cyclic nucleotide-dependent inhibitory signaling interweaves with activating pathways to determine platelet responses

Zoltan Nagy et al.

RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS (2018)

Article Pharmacology & Pharmacy

P2Y12 receptor blockade synergizes strongly with nitric oxide and prostacyclin to inhibit platelet activation

Melissa V. Chan et al.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2016)

Editorial Material Cardiac & Cardiovascular Systems

The Dogged Search for Cryptic Effects of Ticagrelor Wishful Thinking or Real Benefits Beyond P2Y12 Inhibition?

Paul A. Gurbel et al.

CIRCULATION (2016)

Article Cardiac & Cardiovascular Systems

Uric acid and high-residual platelet reactivity in patients treated with clopidogrel or ticagrelor

L. Barbieri et al.

NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES (2016)

Article Cardiac & Cardiovascular Systems

Diabetes mellitus and platelet reactivity in patients under prasugrel or ticagrelor treatment: an observational study

Dimitrios Alexopoulos et al.

CARDIOVASCULAR DIABETOLOGY (2015)

Article Cardiac & Cardiovascular Systems

Body Mass Index and Platelet Reactivity During Dual Antiplatelet Therapy With Clopidogrel or Ticagrelor

Matteo Nardin et al.

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2015)

Article Cardiac & Cardiovascular Systems

Platelet reactivity during ticagrelor maintenance therapy: A patient-level data meta-analysis

Dimitrios Alexopoulos et al.

AMERICAN HEART JOURNAL (2014)

Article Cardiac & Cardiovascular Systems

Adenosine-Mediated Effects of Ticagrelor Evidence and Potential Clinical Relevance

Marco Cattaneo et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2014)

Review Cardiac & Cardiovascular Systems

Consensus and Update on the Definition of On-Treatment Platelet Reactivity to Adenosine Diphosphate Associated With Ischemia and Bleeding

Udaya S. Tantry et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2013)

Article Multidisciplinary Sciences

Blockade of the purinergic P2Y12 receptor greatly increases the platelet inhibitory actions of nitric oxide

Nicholas S. Kirkby et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Biochemistry & Molecular Biology

Ticagrelor induces adenosine triphosphate release from human red blood cells

Jenny Ohman et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)

Article Cardiac & Cardiovascular Systems

Ticagrelor Inhibits Adenosine Uptake In Vitro and Enhances Adenosine-Mediated Hyperemia Responses in a Canine Model

J. J. J. van Giezen et al.

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS (2012)

Article Hematology

Phenotyping vs. genotyping for prediction of clopidogrel efficacy and safety: the PEGASUS-PCI study

J. M. Siller-Matula et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2012)

Letter Cardiac & Cardiovascular Systems

Separate dosing of clopidogrel and omeprazole may improve platelet inhibition on dual antiplatelet therapy

Bernadetta Chyrchel et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2011)

Review Biochemistry & Molecular Biology

Adenosine and blood platelets

Hillary A. Johnston-Cox et al.

PURINERGIC SIGNALLING (2011)

Article Medicine, General & Internal

Cytochrome P-450 Polymorphisms and Response to Clopidogrel.

Jessica L. Mega et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Article Cardiac & Cardiovascular Systems

Impact of platelet reactivity on cardiovascular outcomes in patients with type 2 diabetes mellitus and coronary artery disease

Dominick J. Angiolillo et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2007)

Article Biochemistry & Molecular Biology

Platelet CD36 links hyperlipidemia, oxidant stress and a prothrombotic phenotype

Eugene A. Podrez et al.

NATURE MEDICINE (2007)

Article Hematology

Platelet nitric oxide responsiveness - A novel prognostic marker in acute coronary syndromes

SR Willoughby et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2005)

Article Biochemistry & Molecular Biology

Kinetics of a cellular nitric oxide/cGMP/phosphodiesterase-5 pathway

E Mo et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Review Cardiac & Cardiovascular Systems

The adhesion molecule P-selectin and cardiovascular disease

AD Blann et al.

EUROPEAN HEART JOURNAL (2003)

Article Cardiac & Cardiovascular Systems

Acute, short-term hyperglycemia enhances shear stress-induced platelet activation in patients with Type II diabetes mellitus

P Gresele et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2003)

Article Cardiac & Cardiovascular Systems

Soluble P-selectin and the risk of future cardiovascular events

PM Ridker et al.

CIRCULATION (2001)

Article Peripheral Vascular Disease

Platelet-derived nitric oxide and coronary risk factors

H Ikeda et al.

HYPERTENSION (2000)