4.7 Article

Biomarkers of the L-Arginine/Dimethylarginine/Nitric Oxide Pathway in People with Chronic Airflow Obstruction and Obstructive Sleep Apnoea

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Medicine, General & Internal

Dysregulation of the Nitric Oxide/Dimethylarginine Pathway in Hypoxic Pulmonary Vasoconstriction-Molecular Mechanisms and Clinical Significance

Juliane Hannemann et al.

Summary: The sustained presence of hypoxic pulmonary vasoconstriction may lead to right ventricular hypertrophy and failure, contributing to increased morbidity and mortality in late stages of chronic pulmonary diseases. Elevated levels of asymmetric dimethylarginine (ADMA) may be implicated in the pathogenesis of hypoxic pulmonary vasoconstriction and pulmonary arterial hypertension.

FRONTIERS IN MEDICINE (2022)

Article Clinical Neurology

Association between lung function decline and obstructive sleep apnoea: the ALEC study

Ossur Ingi Emilsson et al.

Summary: The study indicates that individuals with a high risk of obstructive sleep apnoea experience faster lung function decline in the general population, driven by higher BMI and more frequent OSA symptoms. Additionally, the association between OSA symptoms and lung function decline is more pronounced among asthmatics.

SLEEP AND BREATHING (2021)

Article Medicine, General & Internal

Association of Genes of the NO Pathway with Altitude Disease and Hypoxic Pulmonary Hypertension

Juliane Hannemann et al.

Summary: Chronic intermittent hypoxia leads to high-altitude pulmonary hypertension due to high asymmetric dimethylarginine (ADMA) levels. Genetic variations in the dimethylarginine pathway play a role in determining ADMA concentration and the development of HAPH. Different genes are involved in regulating plasma ADMA levels and impacting altitude-related diseases.

JOURNAL OF CLINICAL MEDICINE (2021)

Article Critical Care Medicine

Prevalence and Population-Attributable Risk for Chronic Airflow Obstruction in a Large Multinational Study

Peter Burney et al.

Summary: The study identified smoking and ambient air pollution as major drivers of chronic obstructive pulmonary disease. In addition to smoking, factors such as low education level, dusty occupations, low body mass index, and history of tuberculosis can also increase the risk of chronic airflow obstruction.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2021)

Article Critical Care Medicine

Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis

Adam V. Benjafield et al.

LANCET RESPIRATORY MEDICINE (2019)

Article Respiratory System

Positive correlation of airway resistance and serum asymmetric dimethylarginine level in COPD patients with systemic markers of low-grade inflammation

Gabor Tajti et al.

INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (2017)

Article Geriatrics & Gerontology

Relationship between FEV1 and arterial stiffness in elderly people with chronic obstructive pulmonary disease

Luisa Costanzo et al.

AGING CLINICAL AND EXPERIMENTAL RESEARCH (2017)

Article Respiratory System

L-Arginine Pathway in COPD Patients with Acute Exacerbation: A New Potential Biomarker

Istvan Ruzsics et al.

COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (2016)

Article Biochemistry & Molecular Biology

Effects of Dimethylarginine Dimethylaminohydrolase-1 Overexpression on the Response of the Pulmonary Vasculature to Hypoxia

Adel Bakr et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2013)

Article Hematology

Symmetrical Dimethylarginine Predicts Mortality in the General Population Observations From the Dallas Heart Study

M. Odette Gore et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2013)

Article Cardiac & Cardiovascular Systems

Interaction of the cardiovascular risk marker asymmetric dimethylarginine (ADMA) with the human cationic amino acid transporter 1 (CAT1)

Joachim Strobel et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2012)

Article Cardiac & Cardiovascular Systems

Plasma Asymmetric Dimethylarginine and Incidence of Cardiovascular Disease and Death in the Community

Rainer H. Boeger et al.

CIRCULATION (2009)

Article Respiratory System

Comparison of spirometry criteria for the diagnosis of COPD: results from the BOLD study

W. M. Vollmer et al.

EUROPEAN RESPIRATORY JOURNAL (2009)

Article Biochemical Research Methods

High-throughput liquid chromatographic-tandem mass spectrometric determination of arginine and dimethylated arginine derivatives in human and mouse plasma

Edzard Schwedhelm et al.

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2007)